Diane Wara, MD

Recall Professor
+1 415 476-2171

Diane Wara, MD, is a professor emeritus of pediatrics in the Allergy/Immunology Bone Marrow Transplant Division, director of the Northern California Pediatric HIV Program, and a member of the leadership group for the NIAID-funded domestic and international clinical trials program in HIV (IMPAACT). Her work, along with that of others, led to the successful strategy for the interruption of perinatal transmission in the developed world. Currently, she is working through IMPAACT to extend and modify successful strategies to prevent transmission throughout the developing world. Dr. Wara has authored more than180 publications and, throughout her career, has focused her research on the pathogenesis and treatment strategies of pediatric immune deficiency syndromes (PIDD) and pediatric HIV. She contributed to reports of the first child with adenosine deaminase deficiency as well as treatment strategies for this disorder, including the successful gene transfer in neonates with known ADA deficiency; the first child with purine nucleoside phosphorylase deficiency; the first child with ZAP-70 deficiency; and mutations in IKK -gamma leading to NEMO syndrome. Dr. Wara contributed to reports of the first child with HIV, the first subject to acquire HIV from a blood transfusion, the first report of vertical transmission of hepatitis C, the role(s) of genetic factors as well as neutralizing antibody in the perinatal transmission of HIV as well as long-term progression; the detection and diagnosis of in-utero versus peripartum transmission. She reported the successful interruption of HIV perinatal transmission by the use of intrapartum AZT to the mother and infant prophylaxis for 6 weeks; she reported numerous successful HIV treatment strategies for children and youth. Dr. Wara led the Immunology Division and the UCSF Pediatric Clinical Research Center for over 25 years. She served as member and chair of two NIH study sections as well as member and chair of the NIH Recombinant DNA Advisory Committee (2002-2006). Dr. Wara was elected to the National Academy of Sciences, Institute of Medicine, in 1998.


Brief Report: Markers of Spontaneous Preterm Delivery in Women Living With HIV: Relationship With Protease Inhibitors and Vitamin D.

Journal of acquired immune deficiency syndromes (1999)

Weinberg A, Huo Y, Kacanek D, Patel K, Watts DH, Wara D, Hoffman RM, Klawitter J, Christians U

Ophthalmic manifestations of perinatally acquired HIV in a US cohort of long-term survivors.

The British journal of ophthalmology

Rutar T, Youm J, Porco T, Tilton N, Muskat M, McNamara N, Wara D

Family adversity and autonomic reactivity association with immune changes in HIV-affected school children.

Psychosomatic medicine

Thomas MR, Wara D, Saxton K, Truskier M, Chesney MA, Boyce WT

The effect of prophylaxis on pediatric HIV costs.

AIDS care

Wilson LS, Hensic L, Paoli CJ, Basu R, Christenson M, Moskowitz JT, Wara D

Dendritic cells from humans with hypomorphic mutations in IKBKG/NEMO have impaired mitogen-activated protein kinase activity.

Human mutation

Ma CA, Wang HY, Temmerman S, Zhao Y, Wu L, Hornung RL, Wara D, Jain A

Anti-influenza serum and mucosal antibody responses after administration of live attenuated or inactivated influenza vaccines to HIV-infected children.

Journal of acquired immune deficiency syndromes (1999)

Weinberg A, Song LY, Walker R, Allende M, Fenton T, Patterson-Bartlett J, Nachman S, Kemble G, Yi TT, Defechereux P, Wara D, Read JS, Levin M

Pediatric HIV costs across three treatment eras from 1986 to 2007.


Wilson LS, Basu R, Christenson M, Hensic L, Paoli C, Wara D, Moskowitz JT

Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome.

Clinical immunology (Orlando, Fla.)

Cheng LE, Kanwar B, Tcheurekdjian H, Grenert JP, Muskat M, Heyman MB, McCune JM, Wara DW

Altered iron metabolism in children with human immunodeficiency virus disease.

Pediatric hematology and oncology

Butensky James E, Harmatz P, Lee M, Kennedy C, Petru A, Wara D, Miaskowski C

Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development.

Pediatric rheumatology online journal

Milojevic D, Nguyen KD, Wara D, Mellins ED

Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants.

Antimicrobial agents and chemotherapy

Tremoulet AH, Capparelli EV, Patel P, Acosta EP, Luzuriaga K, Bryson Y, Wara D, Zorrilla C, Holland D, Mirochnick M

Phase I/II trial of intermittent subcutaneous IL-2 administration in pediatric patients with moderate immune suppression: results of Pediatric AIDS Clinical Trials Study 402.

The Journal of allergy and clinical immunology

Pahwa S, Muresan P, Sleasman J, Fenton T, Moye J, Deveikis A, Wara D, Van Dyke R

JC virus granule cell neuronopathy in a child with CD40 ligand deficiency.

Pediatric neurology

Hecht JH, Glenn OA, Wara DW, Wu YW

Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women.

Antimicrobial agents and chemotherapy

Unadkat JD, Wara DW, Hughes MD, Mathias AA, Holland DT, Paul ME, Connor J, Huang S, Nguyen BY, Watts DH, Mofenson LM, Smith E, Deutsch P, Kaiser KA, Tuomala RE

Index of suspicion.

Pediatrics in review

Taylor Z, Butani L, Blumberg D, Cowan M, Wara D, Gopal S, Gavrilita C, Da-Silva S

Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils.


Zhang H, Schaff UY, Green CE, Chen H, Sarantos MR, Hu Y, Wara D, Simon SI, Lowell CA

Antibody responses to hepatitis A virus vaccine in HIV-infected children with evidence of immunologic reconstitution while receiving highly active antiretroviral therapy.

The Journal of infectious diseases

Weinberg A, Gona P, Nachman SA, Defechereux P, Yogev R, Hughes W, Wara D, Spector SA, Read J, Elgie C, Cooper M, Dankner W

Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID).

Clinical immunology (Orlando, Fla.)

Chan B, Wara D, Bastian J, Hershfield MS, Bohnsack J, Azen CG, Parkman R, Weinberg K, Kohn DB

Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen.

AIDS (London, England)

Cohan D, Feakins C, Wara D, Petru A, McNicholl I, Schillinger D, Lu J, Kuritzkes D, Deeks SG

Thrombosis and pediatric Wegener's granulomatosis: acquired and genetic risk factors for hypercoagulability.

Arthritis and rheumatism

von Scheven E, Lu TT, Emery HM, Elder ME, Wara DW

Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study.

The Journal of allergy and clinical immunology

Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, Wara DW, Douglas SD, Luzuriaga K, McFarland EJ, Yogev R, Rathore MH, Levy W, Graham BL, Spector SA

When the time comes to talk about HIV: factors associated with diagnostic disclosure and emotional distress in HIV-infected children.

Journal of acquired immune deficiency syndromes (1999)

Lester P, Chesney M, Cooke M, Weiss R, Whalley P, Perez B, Glidden D, Petru A, Dorenbaum A, Wara D

Safety of 2 recombinant human immunodeficiency virus type 1 (HIV-1) envelope vaccines in neonates born to HIV-1-infected women.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Cunningham CK, Wara DW, Kang M, Fenton T, Hawkins E, McNamara J, Mofenson L, Duliege AM, Francis D, McFarland EJ, Borkowsky W

Ensuring the success of women faculty at AMCs: lessons learned from the National Centers of Excellence in Women's Health.

Academic medicine : journal of the Association of American Medical Colleges

Morahan PS, Voytko ML, Abbuhl S, Means LJ, Wara DW, Thorson J, Cotsonas CE

Recombinant CD4-IgG2 in human immunodeficiency virus type 1-infected children: phase 1/2 study. The Pediatric AIDS Clinical Trials Group Protocol 351 Study Team.

The Journal of infectious diseases

Shearer WT, Israel RJ, Starr S, Fletcher CV, Wara D, Rathore M, Church J, DeVille J, Fenton T, Graham B, Samson P, Staprans S, McNamara J, Moye J, Maddon PJ, Olson WC

A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO).

American journal of human genetics

Zonana J, Elder ME, Schneider LC, Orlow SJ, Moss C, Golabi M, Shapira SK, Farndon PA, Wara DW, Emmal SA, Ferguson BM

Genetic analysis of viral variants selected in transmission of human immunodeficiency viruses to newborns.

AIDS research and human retroviruses

Kliks S, Contag CH, Corliss H, Learn G, Rodrigo A, Wara D, Mullins JI, Levy JA

Shipment impairs lymphocyte proliferative responses to microbial antigens.

Clinical and diagnostic laboratory immunology

Betensky RA, Connick E, Devers J, Landay AL, Nokta M, Plaeger S, Rosenblatt H, Schmitz JL, Valentine F, Wara D, Weinberg A, Lederman HM

Need for an external proficiency testing program for cytokines, chemokines, and plasma markers of immune activation.

Clinical and diagnostic laboratory immunology

Fahey JL, Aziz N, Spritzler J, Plaeger S, Nishanian P, Lathey JL, Seigel J, Landay AL, Kilarui R, Schmitz JL, White C, Wara DW, Akridge R, Cutili J, Douglas SD, Reuben J, Shearer WT, Nokta M, Polland R, Schooley R, Asthana D, Mizrachi Y, Waxdal M

Lymphoproliferative responses to recombinant HIV-1 envelope antigens in neonates and infants receiving gp120 vaccines. AIDS Clinical Trial Group 230 Collaborators.

The Journal of infectious diseases

Borkowsky W, Wara D, Fenton T, McNamara J, Kang M, Mofenson L, McFarland E, Cunningham C, Duliege AM, Francis D, Bryson Y, Burchett S, Spector SA, Frenkel LM, Starr S, Van Dyke R, Jimenez E

Oral manifestations and dental status in paediatric HIV infection.

International journal of paediatric dentistry

Ramos-Gomez FJ, Petru A, Hilton JF, Canchola AJ, Wara D, Greenspan JS

Use of human immunodeficiency virus (HIV) human hyperimmune immunoglobulin in HIV type 1-infected children (Pediatric AIDS clinical trials group protocol 273).

The Journal of infectious diseases

Stiehm ER, Fletcher CV, Mofenson LM, Palumbo PE, Kang M, Fenton T, Sapan CV, Meyer WA, Shearer WT, Hawkins E, Fowler MG, Bouquin P, Purdue L, Sloand EM, Nemo GJ, Wara D, Bryson YJ, Starr SE, Petru A, Burchett S

Cytokine profile of a long-term pediatric HIV survivor with hyper-IgE syndrome and a normal CD4 T-cell count.

The Journal of allergy and clinical immunology

Seroogy CM, Wara DW, Bluth MH, Dorenbaum A, White C, Durkin HG, Elder ME

Pharmacokinetics of dapsone administered daily and weekly in human immunodeficiency virus-infected children.

Antimicrobial agents and chemotherapy

Mirochnick M, Cooper E, McIntosh K, Xu J, Lindsey J, Jacobus D, Mofenson L, Sullivan JL, Dankner W, Frenkel LM, Nachman S, Wara DW, Johnson D, Bonagura VR, Rathore MH, Cunningham CK, McNamara J

Sleep disturbances in children with human immunodeficiency virus infection.


Franck LS, Johnson LM, Lee K, Hepner C, Lambert L, Passeri M, Manio E, Dorenbaum A, Wara D

Immunization with envelope MN rgp120 vaccine in human immunodeficiency virus-infected pregnant women.

The Journal of infectious diseases

Wright PF, Lambert JS, Gorse GJ, Hsieh RH, McElrath MJ, Weinhold K, Wara DW, Anderson EL, Keefer MC, Jackson S, Wagner LJ, Francis DP, Fast PE, McNamara J

Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.

Human gene therapy

Dunbar C, Chang L, Mullen C, Ramsey WJ, Carter C, Kohn D, Parkman R, Lenarsky C, Weinberg K, Wara D, Culver KW, Anderson WF, Leitman S, Fleisher T, Klein H, Shearer G, Clerici M, McGarrity G, Bastian J, Hershfield MS

Planning for children whose parents are dying of HIV/AIDS. American Academy of Pediatrics. Committee on Pediatric AIDS, 1998-1999.


Wilfert C, Aronson JE, Beck DT, Fleischman AR, Kline MW, Mofenson LM, Scott GB, Wara DW, Whitley-Williams PN

Safety and immunogenicity of HIV recombinant envelope vaccines in HIV-infected infants and children. National Institutes of Health-sponsored Pediatric AIDS Clinical Trials Group (ACTG-218).

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association

Lambert JS, McNamara J, Katz SL, Fenton T, Kang M, VanCott TC, Livingston R, Hawkins E, Moye J, Borkowsky W, Johnson D, Yogev R, Duliege AM, Francis D, Gershon A, Wara D, Martin N, Levin M, McSherry G, Smith G

A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team.

The Journal of pediatrics

McKinney RE, Johnson GM, Stanley K, Yong FH, Keller A, O'Donnell KJ, Brouwers P, Mitchell WG, Yogev R, Wara DW, Wiznia A, Mofenson L, McNamara J, Spector SA

T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.

Nature medicine

Kohn DB, Hershfield MS, Carbonaro D, Shigeoka A, Brooks J, Smogorzewska EM, Barsky LW, Chan R, Burotto F, Annett G, Nolta JA, Crooks G, Kapoor N, Elder M, Wara D, Bowen T, Madsen E, Snyder FF, Bastian J, Muul L, Blaese RM, Weinberg K, Parkman R

CD8 cell noncytotoxic antiviral activity in human immunodeficiency virus-infected and -uninfected children.

The Journal of infectious diseases

Levy JA, Hsueh F, Blackbourn DJ, Wara D, Weintrub PS

Comparative trial of two dosages of zalcitabine in zidovudine-experienced children with advanced human immunodeficiency virus disease. Pediatric AIDS Clinical Trials Group.

The Pediatric infectious disease journal

Spector SA, Blanchard S, Wara DW, Oleske JM, McIntosh K, Hodes D, Dankner WM, Salgo M, McNamara J

Transmission of HIV-1 in infants born to seropositive mothers: PCR-amplified proviral DNA detected by flow cytometric analysis of immunoreactive beads.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association

Dorenbaum A, Venkateswaran KS, Yang G, Comeau AM, Wara D, Vyas GN

A descriptive survey of pediatric human immunodeficiency virus-infected long-term survivors.


Nielsen K, McSherry G, Petru A, Frederick T, Wara D, Bryson Y, Martin N, Hutto C, Ammann AJ, Grubman S, Oleske J, Scott GB

Clinical and laboratory characteristics of a large cohort of symptomatic, human immunodeficiency virus-infected infants and children. AIDS Clinical Trials Group Protocol 152 Study Team.

The Pediatric infectious disease journal

Englund JA, Baker CJ, Raskino C, McKinney RE, Lifschitz MH, Petrie B, Fowler MG, Connor JD, Mendez H, O'Donnell K, Wara DW

Toxicities of total-body irradiation for pediatric bone marrow transplantation.

International journal of radiation oncology, biology, physics

Chou RH, Wong GB, Kramer JH, Wara DW, Matthay KK, Crittenden MR, Swift PS, Cowan MJ, Wara WM

Adrenocortical and behavioral predictors of immune responses to starting school.

Pediatric research

Boyce WT, Adams S, Tschann JM, Cohen F, Wara D, Gunnar MR

Life events, cardiovascular reactivity, and risk behavior in adolescent boys.


Liang SW, Jemerin JM, Tschann JM, Irwin CE, Wara DW, Boyce WT

Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1.

The Journal of pediatrics

Just JJ, Abrams E, Louie LG, Urbano R, Wara D, Nicholas SW, Stein Z, King MC

Severe combined immunodeficiency with absence of peripheral blood CD8+ T cells due to ZAP-70 deficiency.

Cellular immunology

Elder ME, Hope TJ, Parslow TG, Umetsu DT, Wara DW, Cowan MJ

Psychobiologic reactivity to stress and childhood respiratory illnesses: results of two prospective studies.

Psychosomatic medicine

Boyce WT, Chesney M, Alkon A, Tschann JM, Adams S, Chesterman B, Cohen F, Kaiser P, Folkman S, Wara D

HIV-1 Tat induces cytokine synthesis by uninfected mononuclear cells.

AIDS (London, England)

Rautonen N, Rautonen J, Martin NL, Wara DW

Features of HIV-1 that could influence maternal-child transmission.


Kliks SC, Wara DW, Landers DV, Levy JA

Association between anti-human immunodeficiency virus type 1 (HIV-1) antibody-dependent cellular cytotoxicity antibody titers at birth and vertical transmission of HIV-1.

The Journal of infectious diseases

Jenkins M, Landers D, Williams-Herman D, Wara D, Viscarello RR, Hammill HA, Kline MW, Shearer WT, Charlebois ED, Kohl S

Antibodies in HIV Tat in Kawasaki disease.

Lancet (London, England)

Rautonen N, White C, Martin NL, Wara DW, Salo E, Pelkonen P, Rautonen J

Anti-tetanus toxoid antibody production after mismatched T cell-depleted bone marrow transplantation.

Journal of clinical immunology

Benkerrou M, Wara DW, Elder M, Dror Y, Merino A, Colombe BW, Garovoy M, Cowan MJ

Performance evaluation in multicenter clinical trials: development of a model by the AIDS Clinical Trials Group.

Controlled clinical trials

Rosendorf LL, Dafni U, Amato DA, Lunghofer B, Bartlett JG, Leedom JM, Wara DW, Armstrong JA, Godfrey E, Sukkestad E

Maternal transmission and diagnosis of human immunodeficiency virus during infancy.

Annals of the New York Academy of Sciences

Wara DW, Luzuriaga K, Martin NL, Sullivan JL, Bryson YJ

Immunologic changes occurring at kindergarten entry predict respiratory illnesses after the Loma Prieta earthquake.

Journal of developmental and behavioral pediatrics : JDBP

Boyce WT, Chesterman EA, Martin N, Folkman S, Cohen F, Wara D

Failure of intravenous pentamidine prophylaxis for Pneumocystis carinii pneumonia.

The Journal of pediatrics

Weintrub PS, Wara DW, Duliege AM

Low number of antibody producing cells in patients with sickle cell anemia.

Immunology letters

Rautonen N, Martin NL, Rautonen J, Rooks Y, Mentzer WC, Wara DW

Proposed definitions for in utero versus intrapartum transmission of HIV-1.

The New England journal of medicine

Bryson YJ, Luzuriaga K, Sullivan JL, Wara DW

Natural history of HIV-associated salivary gland disease.

Oral surgery, oral medicine, and oral pathology

Schiødt M, Dodd CL, Greenspan D, Daniels TE, Chernoff D, Hollander H, Wara D, Greenspan JS

Genetic risk factors for perinatally acquired HIV-1 infection.

Paediatric and perinatal epidemiology

Just J, Louie L, Abrams E, Nicholas SW, Wara D, Stein Z, King MC

A screening test for the detection of anti-HIV-1 IgA in young infants.

Immunological investigations

Martin NL, Rautonen J, Crombleholme W, Rautonen N, Wara DW

Neutrophil function screening in patients with chronic granulomatous disease by a flow cytometric method.


Epling CL, Stites DP, McHugh TM, Chong HO, Blackwood LL, Wara DW

Vertical transmission of hepatitis C virus.

Lancet (London, England)

Thaler MM, Park CK, Landers DV, Wara DW, Houghton M, Veereman-Wauters G, Sweet RL, Han JH

Neopterin in diagnosis of human immunodeficiency virus infection in infants.

Journal of clinical microbiology

Rautonen J, Martin NI, Rautonen N, Wara DW

Total body irradiation and bone marrow transplantation for immunodeficiency disorders in young children.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Halberg FE, Wara WM, Weaver KE, Wara DW, Ablin AR, Matthay KK, Mentzer WC, O'Leary MC, Cowan MJ

ATFresno: a phenotype linking ataxia-telangiectasia with the Nijmegen breakage syndrome.

American journal of human genetics

Curry CJ, O'Lague P, Tsai J, Hutchison HT, Jaspers NG, Wara D, Gatti RA, Hutchinson HT

Parotid gland enlargement and xerostomia associated with labial sialadenitis in HIV-infected patients.

Journal of autoimmunity

Schiødt M, Greenspan D, Daniels TE, Nelson J, Leggott PJ, Wara DW, Greenspan JS

Oral manifestations of pediatric AIDS.


Silverman S, Wara D

Maternally transmitted HIV infection in children.

AIDS (London, England)

Cowan MJ, Walker C, Culver K, Weintrub PS, Wara DW, Levy JA

Production of lymphotoxin and tumor necrosis factor by human neonatal mononuclear cells.

Pediatric research

English BK, Burchett SK, English JD, Ammann AJ, Wara DW, Wilson CB

Naproxen nephrotoxicity in a 2-year-old child.

American journal of diseases of children (1960)

Ray PE, Rigolizzo D, Wara DR, Piel CF

Lymphocyte abnormalities in infants born to drug-abusing mothers.

The Journal of pediatrics

Culver KW, Ammann AJ, Partridge JC, Wong DF, Wara DW, Cowan MJ

Guidelines for the control of perinatally transmitted human immunodeficiency virus infection and care of infected mothers, infants and children.

The Western journal of medicine

Rutherford GW, Oliva GE, Grossman M, Green JR, Wara DW, Shaw NS, Echenberg DF, Wofsy CB, Weinstein DH, Stroud F

Oral manifestation of primary and acquired immunodeficiency diseases in children.

Pediatric dentistry

Leggott PJ, Robertson PB, Greenspan D, Wara DW, Greenspan JS

Haploidentical bone marrow transplantation using soybean agglutinin-processed, T-depleted marrow.

Transplantation proceedings

Matthay K, Wara DW, Ablin AJ, Cowan MJ

Lymphocyte reconstitution in children receiving soybean agglutinin T-depleted bone marrow transplants.

Transplantation proceedings

Cowan MJ, McHugh T, Smith W, Wara D, Matthay K, Ablin A, Casavant C, Stites D

Alpha-fetoprotein levels in immunodeficiency.

The New England journal of medicine

Ammann AJ, Cowan M, Wara D, Heyman M, Thaler MM, Buckley R, Lawton A, Vogler LB, Hirschhorn R

Development of serum IgG subclass levels in children.

Monographs in allergy

Lee SI, Heiner DC, Wara D

Behçet syndrome.

The Journal of pediatrics

Ammann AJ, Johnson A, Fyfe GA, Leonards R, Wara DW, Cowan MJ

Immune regulation: what immunodeficiency disease has taught us.

The Journal of investigative dermatology

Wara DW

Maternal-fetal transfer of pneumococcal capsular polysaccharide antibodies.

American journal of diseases of children (1960)

Chudwin DS, Wara DW, Schiffman G, Artrip SG, Ammann AJ

Epstein-Barr (EB) virus infection in homosexual men in London.

The British journal of venereal diseases

Crawford DH, Weller I, Iliescu V, Wara DW

Prenatal diagnosis of chronic granulomatous disease.

American journal of medical genetics

Matthay KK, Golbus MS, Wara DW, Mentzer WC

Comparison of high-dose and low-dose intravenous immunoglobulin therapy in patients with primary immunodeficiency diseases.

The American journal of medicine

Ochs HD, Fischer SH, Wedgwood RJ, Wara DW, Cowan MJ, Ammann AJ, Saxon A, Budinger MD, Allred RU, Rousell RH

Maternal transmission of acquired immune deficiency syndrome.


Cowan MJ, Hellmann D, Chudwin D, Wara DW, Chang RS, Ammann AJ

Intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency.

Advances in experimental medicine and biology

Cowan MJ, Martin DW, Wara DW, Ammann AJ

Pediatric acquired immunodeficiency syndrome.

Annals of the New York Academy of Sciences

Ammann AJ, Wara DW, Cowan MJ

Significance of a positive antinuclear antibody test in a pediatric population.

American journal of diseases of children (1960)

Chudwin DS, Ammann AJ, Cowan MJ, Wara DW

Chronic active Epstein-Barr virus infections in two immunodeficient patients.

The Journal of pediatrics

Hellmann D, Cowan MJ, Ammann AJ, Wara DW, Chudwin D, Chang RS

Response of agranulocytosis to prolonged antithymocyte globulin therapy.

The Journal of pediatrics

Chudwin DS, Cowan MJ, Greenberg PL, Wara DW, Ammann AJ

Acquired immunodeficiency in an infant: possible transmission by means of blood products.

Lancet (London, England)

Ammann AJ, Cowan MJ, Wara DW, Weintrub P, Dritz S, Goldman H, Perkins HA

Effect of antibody concentration on opsonic requirements for phagocytosis in vitro of Streptococcus pneumoniae types 7 and 19.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

Chudwin DS, Wara DW, Lameris-Martin NB, Ammann AJ

Dipyridamole and intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency.

Birth defects original article series

Ammann AJ, Cowan MJ, Martin DW, Wara DW

Increased serum opsonic activity and antibody concentration in patients with sickle cell disease after pneumococcal polysaccharide immunization.

The Journal of pediatrics

Chudwin DS, Wara DW, Matthay KK, Caulfield MH, Schiffmann G, Mentzer WC, Ammann AJ

Patients with abnormal proportions of T-lymphocyte subsets have reduced in vitro cellular immunity.

Clinical immunology and immunopathology

Chudwin DS, Cowan MJ, Wara DW, Ammann AJ

Aspergillus pneumonia in chronic granulomatous disease: recurrence and long-term outcome.

Acta paediatrica Scandinavica

Chudwin DS, Wara DW, Cowan MJ, Ammann AJ

The DiGeorge syndrome and the fetal alcohol syndrome.

American journal of diseases of children (1960)

Ammann AJ, Wara DW, Cowan MJ, Barrett DJ, Stiehm ER

Posttransfusion syndrome. Rash, eosinophilia, and thrombocytopenia following intrauterine and exchange transfusions.

American journal of diseases of children (1960)

Chudwin DS, Ammann AJ, Wara DW, Cowan MJ, Phibbs RH

Immunochemical studies on thymosin: radioimmunoassay of thymosin alpha 1.

Journal of immunology (Baltimore, Md. : 1950)

McClure JE, Lameris N, Wara DW, Goldstein AL

Use of intravenous gamma-globulin in antibody immunodeficiency: results of a multicenter controlled trial.

Clinical immunology and immunopathology

Ammann AJ, Ashman RF, Buckley RH, Hardie WR, Krantmann HJ, Nelson J, Ochs H, Stiehm ER, Tiller T, Wara DW, Wedgwood R

Clinical and immunologic spectrum of the DiGeorge syndrome.

Journal of clinical & laboratory immunology

Barrett DJ, Ammann AJ, Wara DW, Cowan MJ, Fisher TJ, Stiehm ER

Lung involvement in progressive vaccinia.

The Western journal of medicine

Chudwin DS, Cowan MJ, Wara DW, Johnson AC

Helper cell function of human fetal thymocytes.

Cellular immunology

Barrett DJ, Stenmark S, Wara DW, Ammann AJ

Immunization of immunosuppressed patients with pneumococcal polysaccharide vaccine.

Reviews of infectious diseases

Ammann AJ, Schiffman G, Addiego JE, Wara WM, Wara DW

Role of lymphotoxin in antibody-dependent cell-mediated cytotoxicity (ADCC).

Journal of immunology (Baltimore, Md. : 1950)

Kondo LL, Rosenau W, Wara DW

Spectrum of Sjögren syndrome in children.

The Journal of pediatrics

Chudwin DS, Daniels TE, Wara DW, Ammann AJ, Barrett DJ, Whitcher JP, Cowan MJ

Effect of thymosin on cellular immunity in old age.

Mechanisms of ageing and development

Cowan MJ, Fujiwara P, Wara DW, Ammann AJ

Thymic hormones and the immune system.

Advances in pediatrics

Wara DW

Intermittent ataxia and immunodeficiency with multiple carboxylase deficiencies: a biotin-responsive disorder.

Annals of neurology

Sander JE, Malamud N, Cowan MJ, Packman S, Amman AJ, Wara DW

Immunoregulation in aged humans.

Clinical immunology and immunopathology

Barrett DJ, Stenmark S, Wara DW, Ammann AJ

Thymosin therapy in the DiGeorge syndrome.

The Journal of pediatrics

Barrett DJ, Wara DW, Ammann AJ, Cowan MJ

The prevalence of autoantibodies in T-cell, B-cell, and phagocytic immunodeficiency disorders.

Clinical immunology and immunopathology

Ammann AJ, Wara DW, Pillarisetty RJ, Talal N

Multiple biotin-dependent carboxylase deficiencies associated with defects in T-cell and B-cell immunity.

Lancet (London, England)

Cowan MJ, Wara DW, Packman S, Ammann AJ, Yoshino M, Sweetman L, Nyhan W

Immunosuppression and reconstitution with thymosin after radiation therapy.

International journal of radiation oncology, biology, physics

Wara WM, Wara DW, Ammann AJ, Barnard JL, Phillips TL

Milk precipitins in selective IgA deficiency.

Annals of allergy

Barrett DJ, Bertani L, Wara DW, Ammann AJ

Pneumococcal polysaccharide immunization in infants and children.


Cowan MJ, Ammann AJ, Wara DW, Howie VM, Schultz L, Doyle N, Kaplan M

Immunotherapy and immunopathologic studies in a patient with nucleoside phosphorylase deficiency.

Clinical immunology and immunopathology

Ammann AJ, Wara DW, Allen T

Thymosin treatment of children with primary immunodeficiency disease.

Transplantation proceedings

Wara DW, Ammann AJ

Familial nephrosis, hydrocephalus, thin skin, blue sclerae syndrome: clinical, structural and biochemical studies.

Birth defects original article series

Daentl DL, Townsend JJ, Siegel RC, Godman JR, Piel CF, Wara DW, Bachmann RP

Cellular immunodeficiency associated with nucleoside phosphorylase deficiency. Immunologic and biochemical studies.

Clinical immunology and immunopathology

Sandman R, Ammann AJ, Grose C, Wara DW

Immunologic competence in adults following thymic irradiation in infancy.


Ammann AJ, Wara WM, Wara DW, Phillips TL

Laboratory diagnosis of immunodeficiency disease.

Pediatric clinics of North America

Wara DW

Immunity to Aspergillus in patients with chronic granulomatous disease.

The Journal of pediatrics

Greenberg D, Ammann AJ, Wara DW, Kaltreider HB

Autoantibody, autoimmune disease, and immunodeficiency.

Arthritis and rheumatism

Ammann AJ, Wara DW, Pillarisetty RJ, Talal N

Letter: Effect of thymosin on B-lymphocyte function.

The New England journal of medicine

Wara DW, Ammann AJ

Evaluation of infants and children with recurrent infection.

Current problems in pediatrics

Ammann AJ, Wara DW

Letter: Maternal-fetal graft vs host reaction.

The Journal of pediatrics

Ammann AJ, Wara DW

Serum IgA in the diagnosis of nasopharyngeal and paranasal sinus carcinoma.


Wara WM, Ammann AJ, Wara DW, Phillips TL

Letter: Rosette-forming cells.

Lancet (London, England)

Wara DW, Ammann AJ, Lipow HW, Diamond LK

Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity.

Lancet (London, England)

Giblett ER, Ammann AJ, Wara DW, Sandman R, Diamond LK

Elevated IGA in carcinoma of the nasopharynx.


Wara WM, Wara DW, Phillips TL, Ammann AJ

Persistent Clq deficiency in a patient with a systemic lupus erythematosus-like syndrome.

The Journal of pediatrics

Wara DW, Reiter EO, Doyle NE, Gewurz H, Ammann AJ

Immunosuppression following radiation therapy for carcinoma of the nasopharynx.

The American journal of roentgenology, radium therapy, and nuclear medicine

Wara WM, Phillips TL, Wara DW, Ammann AJ, Smith V

Activation of T-cells rosettes in immunodeficient patients by thymosin.

Annals of the New York Academy of Sciences

Wara DW, Ammann AJ

Thymosin activity in patients with cellular immunodeficiency.

The New England journal of medicine

Wara DW, Goldstein AL, Doyle NE, Ammann AJ

Letter: T-cell rosettes in thyrotoxic Grave's disease.

The New England journal of medicine

Wara DW, Reiter EO, Ammann AJ, Kaplan SL