Elias Botvinick, MD

PROF EMERITUS(WOS)
Medicine
+1 415 353-3817

Elias H. Botvinick, MD, is a Professor in Residence, Co-Director of the Adult Cardiology Non-Invasive Laboratory, and Director of the Cardiac Stress Testing Laboratory at the University of California, San Francisco. Dr. Botvinick received his medical degree from New York University School of Medicine in 1967, and completed a residency in Medicine at Bellevue Hospital in New York, followed by a fellowship in Nuclear Medicine from UCSF in 1976.

Dr. Botvinick’s primary research interest has been scintigraphic methods. His research involves recent applications of the scintigraphic imaging agent indicates its ability to map the regional density of sympathetic nerves and support the hypothesis that an altered balance in the relationship of perfusion and innervation can increase vulnerability to life threatening arrhythmias. Overall, Dr. Botvinick’s research has been a collaborative effort to develop non-invasive graphic and imaging methods for the identification and evaluation of cardiac anatomy and pathophysiology, and apply them to the diagnosis, risk stratification and monitoring of clinical disease.

Dr. Botvinick has written 178 articles, 46 book chapters, 301 abstracts, with 8 significant publications.

Expertise:
Nuclear Medicine and Cardiology

Specialty:
Nuclear cardiology, scintigraphy, cardiovascular diseases

Professional Interests:
Nuclear medicine, nuclear cardiology, PET/CT, MRI, CT, cardiac cardiology, echo cardiology, nuclear magnetic resonance, cardiovascular imaging, stress testing, heart, myocardial perfusion, scintigraphy, coronary, synchrony, synchronization

Education and Training:
• Medical School: New York University School of Medicine, New York
• Internship: Bellevue Hospital, New York - Medicine
• Internship: United States Army, Hospital, Fort Riley
• Residency: Bellevue Hospital, New York - Medicine
• Fellowship: University of California, San Francisco - Nuclear Medicine
• New York State Medical License
• Controlled Substance Registration Certificate
• California State Medical
• Internal Medicine Boards
• Nuclear Medicine Boards
• Cardiovascular Boards
• Certified, Basic Cardiac Life Support
• Certified, Advanced Cardiac Life Support

Publications: 

A combined static-dynamic single-dose imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Sciammarella M, Shrestha UM, Seo Y, Gullberg GT, Botvinick EH

Noninvasive PET quantitative myocardial blood flow with regadenoson for assessing cardiac allograft vasculopathy in orthotopic heart transplantation patients.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Pampaloni MH, Shrestha UM, Sciammarella M, Seo Y, Gullberg GT, Botvinick EH

Utility of Equilibrium Radionuclide Angiogram-Derived Measures of Dyssynchrony to Predict Outcomes in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Badhwar N, James J, Hoffmayer KS, O'Connell JW, Green D, De Marco T, Botvinick EH

Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and (99m)Tc-tetrofosmin: Method and validation.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Shrestha U, Sciammarella M, Alhassen F, Yeghiazarians Y, Ellin J, Verdin E, Boyle A, Seo Y, Botvinick EH, Gullberg GT

Comparison of radionuclide angiographic synchrony analysis to echocardiography and magnetic resonance imaging for the diagnosis of arrhythmogenic right ventricular cardiomyopathy.

Heart rhythm : the official journal of the Heart Rhythm Society

Johnson CJ, Roberts JD, James JH, Hoffmayer KS, Badhwar N, Ku IA, Zhao S, Naeger DM, Rao RK, O'Connell JW, De Marco T, Botvinick EH, Scheinman MM

Erratum to: Isolated right ventricular cardiac sarcoidosis demonstrated by (18)FDG positron emission tomography.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Pampaloni MH, Nazer B, Botvinick E

Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT.

IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium

Shrestha U, Botvinick EH, Yeghiazarians Y, Seo Y, Gullberg GT

Isolated right ventricular cardiac sarcoidosis demonstrated by ¹8FDG positron emission tomography.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Hernandez Pampaloni M, Nazer B, Nazar B, Botvinick E

Imaging synchrony.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Botvinick EH, O'Connell JW, Badhwar N

The variable functional effects of the pacing site in normal and scarred ventricles.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

del Romeral LM, Stillson C, Lesh M, Botvinick E

The relationship of myocardial contraction and electrical excitation--the correlation between scintigraphic phase image analysis and electrophysiologic mapping.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

del Romeral LM, Stillson C, Lesh M, Dae M, Botvinick E

A pilot study of changes in (18)F-FDG uptake, calcification and global metabolic activity of the aorta with aging.

Hellenic journal of nuclear medicine

Bural GG, Torigian DA, Botvinick E, Houseni M, Basu S, Chen W, Alavi A

Localization of ventricular tachycardia exit site and subsequent contraction sequence and functional effects with bedside radionuclide angiography.

JACC. Cardiovascular imaging

Botvinick E, Davis J, Dae M, O'Connell J, Schechtmann N, Abbott J, Morady F, Lanzer P, Iskikian J, Scheinman M

Age-related decrease in cardiopulmonary adrenergic neuronal function in children as assessed by I-123 metaiodobenzylguanidine imaging.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Chen W, Botvinick EH, Alavi A, Zhang Y, Yang S, Perini R, Zhuang H

Myocardial perfusion and function: single photon emission computed tomography.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Hansen CL, Goldstein RA, Akinboboye OO, Berman DS, Botvinick EH, Churchwell KB, Cooke CD, Corbett JR, Cullom SJ, Dahlberg ST, Druz RS, Ficaro EP, Galt JR, Garg RK, Germano G, Heller GV, Henzlova MJ, Hyun MC, Johnson LL, Mann A, McCallister BD, Quaife RA, Ruddy TD, Sundaram SN, Taillefer R, Ward RP, Mahmarian JJ

Equilibrium radionuclide angiocardiography.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Corbett JR, Akinboboye OO, Bacharach SL, Borer JS, Botvinick EH, DePuey EG, Ficaro EP, Hansen CL, Henzlova MJ, Van Kriekinge S

A novel approach to multipinhole SPECT for myocardial perfusion imaging.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Funk T, Kirch DL, Koss JE, Botvinick E, Hasegawa BH

A unique method by which to quantitate synchrony with equilibrium radionuclide angiography.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

O'Connell JW, Schreck C, Moles M, Badwar N, DeMarco T, Olgin J, Lee B, Tseng Z, Kumar U, Botvinick EH

Clinical value of attenuation correction in stress-only Tc-99m sestamibi SPECT imaging.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Heller GV, Bateman TM, Johnson LL, Cullom SJ, Case JA, Galt JR, Garcia EV, Haddock K, Moutray KL, Poston C, Botvinick EH, Fish MB, Follansbee WP, Hayes S, Iskandrian AE, Mahmarian JJ, Vandecker W

Increased right ventricular activity: artifact of camera head misalignment.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Pham KH, Botvinick EH

Scintigraphic blood pool and phase image analysis: the optimal tool for the evaluation of resynchronization therapy.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Botvinick EH

Current practice. The role of noninvasive testing and affect of VANQWISH/FRISC II trials on managing acute coronary syndrome patients.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Allman KC, Godoy I, Olea E, Lekakis J, Zafir N, Metcalfe M, Prigent F, Botvinick EH, Hendrix GH

Intrinsic dual-energy processing of myocardial perfusion images.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Brown JK, Tang HR, Hattner RS, Bocher M, Ratzlaff NW, Kadkade PP, Hasegawa BH, Botvinick EH

Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony.

Journal of the American College of Cardiology

Kerwin WF, Botvinick EH, O'Connell JW, Merrick SH, DeMarco T, Chatterjee K, Scheibly K, Saxon LA

Impact of a home-based walking and resistance training program on quality of life in patients with heart failure.

The American journal of cardiology

Oka RK, De Marco T, Haskell WL, Botvinick E, Dae MW, Bolen K, Chatterjee K

An unusual presentation of non-Hodgkin's lymphoma: a case report.

Clinical nuclear medicine

Challa S, Botvinick EH, Neymark E, Price D, Hawkins RA

Effects of the repeated administration of adenosine and heparin on myocardial perfusion in patients with chronic stable angina pectoris.

The American journal of cardiology

Barron HV, Sciammarella MG, Lenihan K, Michaels AD, Botvinick EH

Is there any advantage to the acquisition of 24-hour thallium images, in the presence of persistent perfusion defects at 4 h after reinjection?

European journal of nuclear medicine

Bobba K, Botvinick EH, Sciammarella MG, Starsken NF, Zhu YY, Lapidus A, Dae MW

Potential added value of three-dimensional reconstruction and display of single photon emission computed tomographic gated blood pool images.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Botvinick EH, O'Connell JW, Kadkade PP, Glickman SL, Dae MW, Cohen TJ, Abbott J, Krishnan R

Nonperfusion applications in nuclear cardiology: report of a task force of the American Society of Nuclear Cardiology.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

DePuey EG, Port S, Wackers FJ, Rozanski A, Botvinick EH, Dae MW, Tamaki N

Fast acquisition of myocardial SPECT images with Tc-99m sestamibi for the diagnosis of coronary artery disease.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Segall GM, Stepp C, Kadkade PP, Dae MW, Botvinick EH

Strategies for extraction of quantitative data from volumetric dynamic cardiac positron emission tomography data.

Cardiology

Huesman RH, Klein GJ, Reutter BW, Coxson PG, Botvinick EH, Budinger TF

Comparison of adenosine to dipyridamole in degree of coronary hyperemic response in heart transplant recipients.

The American journal of cardiology

Chou TM, Sudhir K, Amidon TM, Klinski CS, DeMarco T, Chatterjee K, Botvinick EH

Diagnostic utility of tomographic myocardial perfusion imaging with technetium 99m furifosmin (Q12) compared with thallium 201: results of a phase III multicenter trial.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Hendel RC, Verani MS, Miller DD, Wackers FJ, McMahon M, Cerqueira MD, Botvinick EH, Kvols L, Gerson MC

Cardiac activation mapping by MRI.

Magma (New York, N.Y.)

Knollmann FD, Mäurer J, Kücherer H, Böck JC, O'Connell JW, Botvinick E, Eichstädt HW, Felix R

Variability of normal coronary anatomy: implications for the interpretation of thallium-SPECT myocardial perfusion images in single-vessel disease.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Segall GM, Atwood JE, Botvinick EH, Dae MW, Lucas JR

Segmental analysis of resting echocardiographic function and stress scintigraphic perfusion: implications for myocardial viability.

American heart journal

Foster E, O'Kelly B, LaPidus A, Sandler D, Tucker K, Dae M, Schiller NB, Botvinick EH

A consideration of current clinical options for stress imaging in the diagnosis and evaluation of coronary artery disease.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Botvinick EH

Effects of long-term right ventricular apical pacing on left ventricular perfusion, innervation, function and histology.

Journal of the American College of Cardiology

Lee MA, Dae MW, Langberg JJ, Griffin JC, Chin MC, Finkbeiner WE, O'Connell JW, Botvinick E, Scheinman MM, Rosenqvist M

Effects of canine myocardial infarction on sympathetic efferent neuronal function: scintigraphic and electrophysiologic correlates.

American heart journal

Newman D, Munoz L, Chin M, Franz M, Herre J, Scheinman MM, Botvinick E, Dae M

Hypertrophic cardiomyopathy in the young: another form of ischemic cardiomyopathy?

Journal of the American College of Cardiology

Botvinick EH, Dae MW, Krishnan R, Ewing S

The proper tool for the job.

Journal of the American College of Cardiology

Botvinick EH

Basal interventricular septal thallium-201 defects: real or artifact?

Clinical nuclear medicine

Starksen NF, O'Connell W, Dae MW, Botvinick EH

A quantitative assessment of patient motion and its effect on myocardial perfusion SPECT images.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Botvinick EH, Zhu YY, O'Connell WJ, Dae MW

Diagnostic and prognostic value of ambulatory electrocardiographic monitoring.

American heart journal

Munoz del Romeral L, Dae MW, Ports TA, Botvinick EH

Scintigraphic assessment of MIBG uptake in globally denervated human and canine hearts--implications for clinical studies.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Dae MW, De Marco T, Botvinick EH, O'Connell JW, Hattner RS, Huberty JP, Yuen-Green MS

Usefulness of adenosine in augmenting ventricular preexcitation for noninvasive localization of accessory pathways.

The American journal of cardiology

Cohen TJ, Tucker KJ, Abbott JA, Botvinick EH, Foster E, Schiller NB, O'Connell JW, Scheinman MM

The applications of adenosine in noninvasive cardiac imaging.

Herz

Tucker KJ, Cohen TJ, Botvinick EH, Schiller NB

Advances in myocardial scintigraphy in coronary heart disease.

American journal of cardiac imaging

Botvinick EH

Two-dimensional echocardiographic phase analysis. Its potential for noninvasive localization of accessory pathways in patients with Wolff-Parkinson-White syndrome.

Circulation

Kuecherer HF, Abbott JA, Botvinick EH, Scheinman ED, O'Connell JW, Scheinman MM, Foster E, Schiller NB

Dipyridamole perfusion scintigraphy.

Seminars in nuclear medicine

Botvinick EH, Dae MW

Comparison of the findings on preoperative dipyridamole perfusion scintigraphy and intraoperative transesophageal echocardiography: implications regarding the identification of myocardium at ischemic risk.

Journal of the American College of Cardiology

Watters TA, Botvinick EH, Dae MW, Cahalan M, Urbanowicz J, Benefiel DJ, Schiller NB, Goldstone G, Reilly L, Stoney RJ

Phase image triangulation of accessory pathways in patients undergoing catheter ablation of posteroseptal pathways.

Pacing and clinical electrophysiology : PACE

Oeff M, Scheinman MM, Abbott JA, Botvinick EH, Griffin JC, Herre JM, Dae MW

Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction.

Journal of the American College of Cardiology

Dae MW, Herre JM, O'Connell JW, Botvinick EH, Newman D, Munoz L

Relative importance of activation sequence compared to atrioventricular synchrony in left ventricular function.

The American journal of cardiology

Rosenqvist M, Isaaz K, Botvinick EH, Dae MW, Cockrell J, Abbott JA, Schiller NB, Griffin JC

Dipyridamole perfusion scintigraphy: the experience with its application in one hundred seventy patients with known or suspected unstable angina.

American heart journal

Zhu YY, Chung WS, Botvinick EH, Dae MW, Lim AD, Ports TA, Danforth JW, Wolfe CL, Goldschlager N, Chatterjee K

Benefits of physiologic atrioventricular synchronization for pacing with an exercise rate response.

The American journal of cardiology

Landzberg JS, Franklin JO, Mahawar SK, Himelman RB, Botvinick EH, Schiller NB, Springer MJ, Griffin JC

Imaging of the heart using metaiodobenzylguanidine.

Journal of thoracic imaging

Dae MW, Botvinick EH

Late reversibility: a viability issue.

Journal of the American College of Cardiology

Botvinick EH

Epicardial and endocardial localized 31P magnetic resonance spectroscopy: evidence for metabolic heterogeneity during regional ischemia.

Magnetic resonance in medicine

Gober JR, Schaefer S, Camacho SA, DeGroot M, Obregon R, Botvinick EH, Weiner M, Massie B

Oblique reformatting of multislice magnetic resonance images for improved visualization of coronary arteries.

Journal of digital imaging

Hylton NM, Chung WS, Botvinick EH, Schiller NB, Sheldon P, Kaufman L

"Hot spot" imaging agents for acute myocardial infarction.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Botvinick EH

Blood pool scintigraphy.

Cardiology clinics

Botvinick EH, Dae MW, O'Connell JW

Noninvasive assessment of cardiomyopathy in normotensive diabetic patients between 20 and 50 years old.

The American journal of medicine

Bouchard A, Sanz N, Botvinick EH, Phillips N, Heilbron D, Byrd BF, Karam JH, Schiller NB

Response of myocardial metabolites to graded regional ischemia: 31P NMR spectroscopy of porcine myocardium in vivo.

Circulation research

Schaefer S, Camacho SA, Gober J, Obregon RG, DeGroot MA, Botvinick EH, Massie B, Weiner MW

Value of color Doppler estimation of regurgitant volume in patients with chronic aortic insufficiency.

American heart journal

Bouchard A, Yock P, Schiller NB, Blumlein S, Botvinick EH, Greenberg B, Cheitlin M, Massie BM

ECG left anterior fascicular block reveals diverse patterns on scintigraphic phase analysis.

American heart journal

Dae M, Wen YM, Botvinick EH, Scheinman M

The scintigraphic characteristics of ventricular pre-excitation through Mahaim fibers with the use of phase analysis.

Journal of the American College of Cardiology

Schechtmann N, Botvinick EH, Dae M, Scheinman MM, O'Connell JW, Davis J, Winston S, Schwartz A, Abbott J

Scintigraphic assessment of regional cardiac adrenergic innervation.

Circulation

Dae MW, O'Connell JW, Botvinick EH, Ahearn T, Yee E, Huberty JP, Mori H, Chin MC, Hattner RS, Herre JM

Nuclear magnetic resonance imaging-guided phosphorus-31 spectroscopy of the human heart.

Journal of the American College of Cardiology

Schaefer S, Gober J, Valenza M, Karczmar GS, Matson GB, Camacho SA, Botvinick EH, Massie B, Weiner MW

In vivo alterations of high-energy phosphates and intracellular pH during reversible ischemia in pigs: a 31P magnetic resonance spectroscopy study.

American heart journal

Camacho SA, Lanzer P, Toy BJ, Gober J, Valenza M, Botvinick EH, Weiner MW

Gallium lung scintigraphy in amiodarone pulmonary toxicity.

Chest

Zhu YY, Botvinick E, Dae M, Golden J, Hattner R, Scheinman M

Estimation of the functional and anatomic extent of myocardial infarction using magnetic resonance imaging.

American heart journal

White RD, Holt WW, Cheitlin MD, Cassidy MM, Ports TA, Lim AD, Botvinick EH, Higgins CB

Dipyridamole myocardial perfusion scintigraphy.

The Western journal of medicine

Botvinick EH, Dae M

Improvement in myocardial performance without a decrease in high-energy phosphate metabolites after isoproterenol in Syrian cardiomyopathic hamsters.

Circulation

Camacho SA, Wikman-Coffelt J, Wu ST, Watters TA, Botvinick EH, Sievers R, James TL, Jasmin G, Parmley WW

Substrate regulation of the nucleotide pool during regional ischaemia and reperfusion in an isolated rat heart preparation: a phosphorus-31 magnetic resonance spectroscopy analysis.

Cardiovascular research

Camacho SA, Parmley WW, James TL, Abe H, Wu ST, Botvinick EH, Watters TA, Schiller N, Sievers R, Wikman-Coffelt J

Analysis of thallium-201 "washout" from parametric color coded images.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Botvinick EH, O'Connell WJ, Dae MW, Hattner RS, Schechtmann NM

Chemomechanics of altered perfusion pressure in rat hearts.

Basic research in cardiology

Watters TA, Botvinick E, Parmley WW, Wu S, Wikman-Coffelt J

Quantitation of intracardiac shunts by cine-CT.

Journal of computer assisted tomography

Garrett JS, Jaschke W, Aherne T, Botvinick EH, Higgins CB, Lipton MJ

Segmental evaluation of left ventricular wall motion after myocardial infarction: magnetic resonance imaging versus echocardiography.

American heart journal

White RD, Cassidy MM, Cheitlin MD, Emilson B, Ports TA, Lim AD, Botvinick EH, Schiller NB, Higgins CB

Factors influencing myocardial response to metabolic acidosis in isolated rat hearts.

The American journal of physiology

Watters TA, Wendland MF, Parmley WW, James TL, Botvinick EH, Wu ST, Sievers R, Wikman-Coffelt J

Augmented preexcitation assessed by scintigraphic phase analysis during atrial pacing.

American heart journal

Botvinick E, Schechtmann N, Dae M, Scheinman M, Davis J, Herre J, Iskikian T, Abbott J

Effects of altered coronary perfusion pressure on function and metabolism of normal and cardiomyopathic hamster hearts.

Journal of molecular and cellular cardiology

Bouchard A, Watters TA, Wu S, Parmley WW, Stone RD, Botvinick E, Sievers R, Jasmin G, Wikman-Coffelt J

Hemodynamic and clinical evaluation of piroximone, a new inotrope-vasodilator agent, in severe congestive heart failure.

Journal of the American College of Cardiology

Axelrod RJ, De Marco T, Dae M, Botvinick EH, Chatterjee K

Advances in noninvasive cardiovascular imaging: implications for the anesthesiologist.

Anesthesiology

Cahalan MK, Litt L, Botvinick EH, Schiller NB

Left ventricular dimensions and mechanics in distance runners.

American heart journal

Mickelson JK, Byrd BF, Bouchard A, Botvinick EH, Schiller NB

Quantitation of regional myocardial function by cine computed tomography: pharmacologic changes in wall thickness.

Journal of the American College of Cardiology

Lanzer P, Garrett J, Lipton MJ, Gould R, Sievers R, O'Connell W, Botvinick E, Higgins CB

Quantitation of mitral regurgitation by Doppler echocardiography.

Circulation

Blumlein S, Bouchard A, Schiller NB, Dae M, Byrd BF, Ports T, Botvinick EH

Cine-computed tomography of Ebstein anomaly.

Journal of computer assisted tomography

Garrett JS, Schiller NB, Botvinick EH, Higgins CB, Lipton MJ

Poor correlation between pulmonary arterial wedge pressure and left ventricular end-diastolic volume after coronary artery bypass graft surgery.

Anesthesiology

Hansen RM, Viquerat CE, Matthay MA, Wiener-Kronish JP, DeMarco T, Bahtia S, Marks JD, Botvinick EH, Chatterjee K

Differentiation of reversible and irreversible myocardial injury by MR imaging with and without gadolinium-DTPA.

Radiology

McNamara MT, Tscholakoff D, Revel D, Soulen R, Schechtmann N, Botvinick E, Higgins CB

Measurement of cardiac output by cine computed tomography.

The American journal of cardiology

Garrett JS, Lanzer P, Jaschke W, Botvinick E, Sievers R, Higgins CB, Lipton MJ

Interaction of "supplementary" scintigraphic indicators of ischemia and stress electrocardiography in the diagnosis of multivessel coronary disease.

Journal of the American College of Cardiology

Canhasi B, Dae M, Botvinick E, Lanzer P, Schechtmann N, Faulkner D, O'Connell W, Schiller N

Undrained bloody pericardial effusion in the early postoperative period after coronary bypass surgery: a prospective blood pool study.

American heart journal

Viquerat CE, Hansen RM, Botvinick EH, Dae MW, Wiener-Kronish JP, Matthay MA

The effects of coronary angioplasty and reperfusion on distribution of myocardial flow.

Circulation

Wahr DW, Ports TA, Botvinick EH, Dae M, Schechtmann N, Huberty J, Hattner RS, O'Connell JW, Turley K

[Imaging of the heart using nuclear magnetic resonance tomography. I: Tomography].

Zeitschrift fu¨r Kardiologie

Lanzer PA, Botvinick EH, Higgins CB

The etiology and implications of dense cavitary "photopenia" on myocardial perfusion scintigraphy.

Investigative radiology

Dae M, Canhasi B, Botvinick E, Olvera S, Schechtmann N, Engelstad B, Hattner R, Schiller N, O'Connell W, Faulkner D

Magnetic resonance imaging of the heart: a review of the experience in 172 subjects.

Radiology

Higgins CB, Byrd BF, McNamara MT, Lanzer P, Lipton MJ, Botvinick E, Schiller NB, Crooks LE, Kaufman L

ECG-synchronized cardiac MR imaging: method and evaluation.

Radiology

Lanzer P, Barta C, Botvinick EH, Wiesendanger HU, Modin G, Higgins CB

Normal cardiac dimensions by magnetic resonance imaging.

The American journal of cardiology

Byrd BF, Schiller NB, Botvinick EH, Higgins CB

Magnetic resonance imaging in hypertrophic cardiomyopathy.

The American journal of cardiology

Higgins CB, Byrd BF, Stark D, McNamara M, Lanzer P, Lipton MJ, Schiller NB, Botvinick E, Chatterjee K

Detection and characterization of acute myocardial infarction in man with use of gated magnetic resonance.

Circulation

McNamara MT, Higgins CB, Schechtmann N, Botvinick E, Lipton MJ, Chatterjee K, Amparo EG

Assessment of left intraventricular block by scintigraphic analysis.

Chinese medical journal

Wen YM, Botvinick EH, Sheinman MM

Assessment of cardiac anatomy using nuclear magnetic resonance imaging.

Journal of the American College of Cardiology

Higgins CB, Lanzer P, Stark D, Botvinick E, Schiller NB, Lipton MJ, Crooks LE, Kaufman L

Magnetic resonance (MR) imaging of aorta and pulmonary circulation. Initial experience with ECG-gating.

Annales de radiologie

Lallemand D, Gooding CA, Wesbey GE, Brasch RC, Botvinick E, Lanzer P, McNamara MT

Cardiosynchronous MRI intensity changes of the great vessels and pulmonary circulation. A preliminary report.

Annales de radiologie

Lallemand D, Wesbey GE, Gooding CA, Ehman R, Brasch RC, Ortendahl D, McNamara MT, Lanzer P, Botvinick E, Crooks E

The scintigraphic identification of "severe myocardial ischemia".

Giornale italiano di cardiologia

Botvinick EH

Magnetic resonance imaging strategies for heart studies.

Radiology

Crooks LE, Barker B, Chang H, Feinberg D, Hoenninger JC, Watts JC, Arakawa M, Kaufman L, Sheldon PE, Botvinick E

Mechanisms of improved left ventricular function following intravenous MDL 17,043 in patients with severe chronic heart failure.

American heart journal

Kereiakes DJ, Viquerat C, Lanzer P, Botvinick EH, Spangenberg R, Buckingham M, Parmley WW, Chatterjee K

Phase image characterization of localized and generalized left ventricular contraction abnormalities.

Journal of the American College of Cardiology

Frais M, Botvinick E, Shosa D, O'Connell W, Pacheco Alvarez J, Dae M, Hattner R, Faulkner D

Catheter-induced His bundle ablation in a patient with reentrant tachycardia associated with a nodoventricular tract.

Journal of the American College of Cardiology

Bhandari A, Morady F, Shen EN, Schwartz AB, Botvinick E, Scheinman MM

Right ventricular myocardial infarction with ventricular septal rupture.

American heart journal

Kereiakes DJ, Ports TA, Botvinick EH, Schiller NB, Turley K, Chatterjee K

Improved regional ventricular function after successful surgical revascularization.

Journal of the American College of Cardiology

Brundage BH, Massie BM, Botvinick EH

Phase image evaluation of patients with ventricular pre-excitation syndromes.

Journal of the American College of Cardiology

Botvinick E, Frais M, O'Connell W, Faulkner D, Scheinman M, Morady F, Sung R, Shosa D, Dae M

Imaging by nuclear magnetic resonance in patients with chronic ischemic heart disease.

Circulation

Higgins CB, Lanzer P, Stark D, Botvinick E, Schiller NB, Crooks L, Kaufman L, Lipton MJ

Cardiac imaging using gated magnetic resonance.

Radiology

Lanzer P, Botvinick EH, Schiller NB, Crooks LE, Arakawa M, Kaufman L, Davis PL, Herfkens R, Lipton MJ, Higgins CB

The functional implications of scintigraphic measures of myocardial ischemia and infarction.

American heart journal

Misbach GA, Botvinick EH, Tyberg JV, Parmley WW, Dunn RF, Frais M

Diagnostic test use in different practice settings. A controlled comparison.

Archives of internal medicine

Hlatky MA, Lee KL, Botvinick EH, Brundage BH

Evaluation of the post-coronary artery bypass patient by myocardial perfusion scintigraphy and computed tomography.

AJR. American journal of roentgenology

Engelstad BL, Wagner S, Herfkens R, Botvinick E, Brundage B, Lipton M

Cardiovascular imaging with nuclear magnetic resonance.

Cardiology clinics

Higgins CB, Botvinick EH, Lanzer P, Herfkens R, Lipton MJ, Crooks LE, Kaufman L

Volume loading improves low cardiac output in experimental right ventricular infarction.

Journal of the American College of Cardiology

Goldstein JA, Vlahakes GJ, Verrier ED, Schiller NB, Botvinick E, Tyberg JV, Parmley WW, Chatterjee K

Nuclear magnetic resonance imaging of the cardiovascular system: normal and pathologic findings.

Radiology

Herfkens RJ, Higgins CB, Hricak H, Lipton MJ, Crooks LE, Lanzer P, Botvinick E, Brundage B, Sheldon PE, Kaufman L

Late prognostic value of scintigraphic parameters of acute myocardial infarction size in complicated myocardial infarction without heart failure.

The American journal of cardiology

Botvinick EH, Perez-Gonzalez JF, Dunn R, Ports T, Chatterjee K, Parmley W

Variability in coronary hemodynamics in response to ergonovine in patients with normal coronary arteries and atypical chest pain.

Journal of the American College of Cardiology

Schwartz AB, Donmichael TA, Botvinick EH, Ishimori T, Parmley WW, Chatterjee K

Electrophysiologic mechanism of exercise-induced sustained ventricular tachycardia.

The American journal of cardiology

Sung RJ, Shen EN, Morady F, Scheinman MM, Hess D, Botvinick EH

The late prognostic value of acute scintigraphic measurement of myocardial infarction size.

Circulation

Perez-Gonzalez J, Botvinick EH, Dunn R, Rahimtoola S, Ports T, Chatterjee K, Parmley WW

The independent value of exercise thallium scintigraphy to physicians.

Circulation

Hlatky M, Botvinick E, Brundage B

An accurate means of detecting and characterizing abnormal patterns of ventricular activation by phase image analysis.

The American journal of cardiology

Botvinick EH, Frais MA, Shosa DW, O'Connell JW, Pacheco-Alvarez JA, Scheinman M, Hattner RS, Morady F, Faulkner DB

Phase image characterization of ventricular contraction in left and right bundle branch block.

The American journal of cardiology

Frais MA, Botvinick EH, Shosa DW, O'Connell WJ, Scheinman MM, Hattner RS, Morady F

Diagnostic accuracy of cardiologists compared with probability calculations using Bayes' rule.

The American journal of cardiology

Hlatky M, Botvinick E, Brundage B

The significance of nitroglycerin-induced changes in ventricular function after acute myocardial infarction.

The American journal of cardiology

Dunn RF, Botvinick EH, Benge W, Chatterjee K, Parmley WW

Hemodynamic benefit of atrial pacing in right ventricular myocardial infarction.

Annals of internal medicine

Topol EJ, Goldschlager N, Ports TA, Dicarlo LA, Schiller NB, Botvinick EH, Chatterjee K

The phase image: its relationship to patterns of contraction and conduction.

Circulation

Botvinick E, Dunn R, Frais M, O'Connell W, Shosa D, Herfkens R, Scheinman M

The inconsistent pattern of thallium defects: a clue to the false positive perfusion scintigram.

The American journal of cardiology

Dunn RF, Wolff L, Wagner S, Botvinick EH

Detecting and localizing peripheral arterial disease: assessment of 201Tl scintigraphy.

AJR. American journal of roentgenology

Seder JS, Botvinick EH, Rahimtoola SH, Goldstone J, Price DC

Contrast enhancement of thallium-201 myocardial scintigrams: improved sensitivity with diminished specificity in coronary disease detection.

American heart journal

Massie B, Botvinick E, Arnold S, Shames D, Brundage B, Hanlon JT, Sheldon K

Evaluation of left ventricular performance by gated radionuclide angiography.

Clinical nuclear medicine

Greenberg BH, Drew D, Botvinick EH, Werner JA, Klausner SC, Shames DM, Parmley WW

Myocardial perfusion scintigraphy.

Archives of internal medicine

Botvinick EH

Left ventricular volume from paired biplane two-dimensional echocardiography.

Circulation

Schiller NB, Acquatella H, Ports TA, Drew D, Goerke J, Ringertz H, Silverman NH, Brundage B, Botvinick EH, Boswell R, Carlsson E, Parmley WW

Myocardial scintigraphy with technetium-99m stannous pyrophosphate: an insensitive test for nontransmural myocardial infarction.

The American journal of cardiology

Massie BM, Botvinick EH, Werner JA, Chatterjee K, Parmley WW

Gallium-67 uptake in silent myocardial infarction: a case report.

Radiology

Schor RA, Massie BM, Botvinick EH, Shames DM

The specificity of pyrophosphate myocardial scintigrams in patients with prior myocardial infarction: concise communication.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Botvinick EH, Shames DM, Sharpe DN, Klausner SC, Werner JA, Chatterjee K, Parmley WW

Thallium-201 myocardial perfusion scintigraphy to evaluate patients after coronary bypass surgery.

The American journal of cardiology

Greenberg BH, Hart R, Botvinick EH, Werner JA, Brundage BH, Shames DM, Chatterjee K, Parmley WW

Beneficial effects of hydralazine in severe mitral regurgitation.

Circulation

Greenberg BH, Massie BM, Brundage BH, Botvinick EH, Parmley WW, Chatterjee K

The noninvasive diagnosis of right ventricular infarction.

Circulation

Sharpe DN, Botvinick EH, Shames DM, Schiller NB, Massie BM, Chatterjee K, Parmley WW

The clinical estimation of acute myocardial infarct size with 99mTechnetium pyrophosphate scintigraphy.

Circulation

Sharpe DN, Botvinick EH, Shames DM, Norman A, Chatterjee K, Parmley WW

Myocardial scintigraphy in coronary artery disease.

Cleveland Clinic quarterly

Botvinick EH, Shames D, Parmley WW

Acute myocardial infarction: clinical application of technetium 99m stannous pyrophosphate infarct scintigraphy.

The Western journal of medicine

Werner JA, Botvinick EH, Shames DM, Parmley WW

The application of radionuclide infarct scintigraphy to diagnose perioperative myocardial infarction following revascularization.

Circulation

Klausner SC, Botvinick EH, Shames D, Ullyot DJ, Fishman NH, Roe BB, Ebert PA, Chatterjee K, Parmley WW

Myocardial stress perfusion scintigraphy with rubidium-81 versus stress electrocardiography.

The American journal of cardiology

Botvinick EH, Shames DM, Gershengorn KM, Carlsson E, Ratshin RA, Parmley WW

The hemodynamics of coronary arterial stenosis.

Cardiovascular clinics

Tyberg JV, Massie BM, Botvinick EH, Parmley W

Myocardial infarction in closed-chest dogs: a simplified method for production.

Journal of applied physiology

Lappin HA, Botvinick EH, Parmley WW, Tyberg JV

Noninvasive quantitation of myocardial infarction with technetium 99m pyrophosphate.

Circulation

Botvinick EH, Shames D, Lappin H, Tyberg JV, Townsend R, Parmley WW

Echocardiographic demonstration of early mitral valve closure in severe aortic insufficiency. Its clinical implications.

Circulation

Botvinick EH, Schiller NB, Wickramasekaran R, Klausner SC, Gertz E