Jeanine Wiener-Kronish, MD

PROF EMERITUS(WOS)
Anesthesia
+1 415 476-1935
Publications: 

Intubation With Video Laryngoscopy vs Direct Laryngoscopy.

JAMA

Saddawi-Konefka D, Baker KH, Wiener-Kronish JP

Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial.

The Lancet. Respiratory medicine

Wilson JG, Liu KD, Zhuo H, Caballero L, McMillan M, Fang X, Cosgrove K, Vojnik R, Calfee CS, Lee JW, Rogers AJ, Levitt J, Wiener-Kronish J, Bajwa EK, Leavitt A, McKenna D, Thompson BT, Matthay MA

Association between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: a review.

Critical care (London, England)

Sawa T, Shimizu M, Moriyama K, Wiener-Kronish JP

Research at the Harvard Anesthesia Departments.

Anesthesiology

Forman SA, Miller KW, Talmor D, Hickey P, Strichartz G, Wiener-Kronish J

Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome.

Annals of intensive care

Liu KD, Wilson JG, Zhuo H, Caballero L, McMillan ML, Fang X, Cosgrove K, Calfee CS, Lee JW, Kangelaris KN, Gotts JE, Rogers AJ, Levitt JE, Wiener-Kronish JP, Delucchi KL, Leavitt AD, McKenna DH, Thompson BT, Matthay MA

Blood transfusions and infected lungs--worse outcomes?*.

Critical care medicine

Wiener-Kronish J, Nozari A

Rearrangement of a large novel Pseudomonas aeruginosa gene island in strains isolated from a patient developing ventilator-associated pneumonia.

Journal of clinical microbiology

Singh G, Srinivasan R, Cheng J, Peng Z, Fujimura K, Baek MS, Panzer AR, Tringe SG, Chen F, Sorek R, Weng L, Bristow J, Wiener-Kronish JP, Lynch SV

In reply.

Anesthesiology

Fleisher LA, Evers AS, Wiener-Kronish J, Ulatowski JA

What are we looking for? The question of resident selection.

Anesthesiology

Fleisher LA, Evers AS, Wiener-Kronish J, Ulatowski JA

Continuing aspirin in the perioperative patient.

Annals of surgery

Connors JM, Wiener-Kronish JP

Treating bacterial virulence systems: we are not there yet.

Intensive care medicine

Huang YJ, Bittner EA, Frank D, Wiener-Kronish J

From microbe to microbiota: considering microbial community composition in infections and airway diseases.

American journal of respiratory and critical care medicine

Huang YJ, Lynch SV, Wiener-Kronish JP

Strain-dependent induction of neutrophil histamine production and cell death by Pseudomonas aeruginosa.

Journal of leukocyte biology

Xu X, Zhang H, Song Y, Lynch SV, Lowell CA, Wiener-Kronish JP, Caughey GH

Therapies against virulence products of Staphylococcus aureus and Pseudomonas aeruginosa.

Seminars in respiratory and critical care medicine

Wiener-Kronish JP, Pittet JF

Differences in biofilm formation and antimicrobial resistance of Pseudomonas aeruginosa isolated from airways of mechanically ventilated patients and cystic fibrosis patients.

International journal of antimicrobial agents

Fricks-Lima J, Hendrickson CM, Allgaier M, Zhuo H, Wiener-Kronish JP, Lynch SV, Yang K

Newer technology is not always better.

Critical care medicine

Albrecht M, Wiener-Kronish JP

Plasminogen activation inhibitor concentrations in bronchoalveolar lavage fluid distinguishes ventilator-associated pneumonia from colonization in mechanically ventilated pediatric patients.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

Srinivasan R, Song Y, Wiener-Kronish J, Flori HR

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma.

The Journal of allergy and clinical immunology

Huang YJ, Nelson CE, Brodie EL, Desantis TZ, Baek MS, Liu J, Woyke T, Allgaier M, Bristow J, Wiener-Kronish JP, Sutherland ER, King TS, Icitovic N, Martin RJ, Calhoun WJ, Castro M, Denlinger LC, Dimango E, Kraft M, Peters SP, Wasserman SI, Wechsler ME, Boushey HA, Lynch SV

Pseudomonas aeruginosa: acute lung injury or ventilator-associated pneumonia?

Minerva anestesiologica

Berra L, Sampson J, Wiener-Kronish J

1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit.

The Journal of trauma

Cohen MJ, Serkova NJ, Wiener-Kronish J, Pittet JF, Niemann CU

Secretion of Pseudomonas aeruginosa type III cytotoxins is dependent on pseudomonas quinolone signal concentration.

Microbial pathogenesis

Singh G, Wu B, Baek MS, Camargo A, Nguyen A, Slusher NA, Srinivasan R, Wiener-Kronish JP, Lynch SV

Polymorphisms in the Pseudomonas aeruginosa type III secretion protein, PcrV - implications for anti-PcrV immunotherapy.

Microbial pathogenesis

Lynch SV, Flanagan JL, Sawa T, Fang A, Baek MS, Rubio-Mills A, Ajayi T, Yanagihara K, Hirakata Y, Kohno S, Misset B, Nguyen JC, Wiener-Kronish JP

A persistent and diverse airway microbiota present during chronic obstructive pulmonary disease exacerbations.

Omics : a journal of integrative biology

Huang YJ, Kim E, Cox MJ, Brodie EL, Brown R, Wiener-Kronish JP, Lynch SV

Mechanisms of bacterial virulence in pulmonary infections.

Current opinion in critical care

Moskowitz SM, Wiener-Kronish JP

Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia.

The Journal of trauma

Cohen MJ, Bir N, Rahn P, Dotson R, Brohi K, Chesebro BB, Mackersie R, Carles M, Wiener-Kronish J, Pittet JF

The United States critical illness and injury trials group: an introduction.

The Journal of trauma

Cobb JP, Cairns CB, Bulger E, Wong HR, Parsons PE, Angus DC, Gentile NT, Hoyt DB, Schwinn DA, Wiener-Kronish JP, Upperman JS

Training the next generation of research mentors: the University of California, San Francisco, Clinical & Translational Science Institute Mentor Development Program.

Clinical and translational science

Feldman MD, Huang L, Guglielmo BJ, Jordan R, Kahn J, Creasman JM, Wiener-Kronish JP, Lee KA, Tehrani A, Yaffe K, Brown JS

Matrix metalloproteases in bronchoalveolar lavage fluid of patients with type III Pseudomonas aeruginosa pneumonia.

The Journal of infection

El-Solh AA, Amsterdam D, Alhajhusain A, Akinnusi ME, Saliba RG, Lynch SV, Wiener-Kronish JP

4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumonia.

Anesthesiology

Sapru A, Hansen H, Ajayi T, Brown R, Garcia O, Zhuo H, Wiemels J, Matthay MA, Wiener-Kronish J

A prospective study of ventilator-associated pneumonia in children.

Pediatrics

Srinivasan R, Asselin J, Gildengorin G, Wiener-Kronish J, Flori HR

An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity.

Infection and immunity

Baer M, Sawa T, Flynn P, Luehrsen K, Martinez D, Wiener-Kronish JP, Yarranton G, Bebbington C

2008 in review: advancing medicine in anesthesiology.

Anesthesiology

Eisenach JC, Borgeat A, Bosnjak ZJ, Brennan TJ, Kersten JR, Kochs E, Lerman J, Warner DS, Wiener-Kronish JP

Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia.

American journal of physiology. Lung cellular and molecular physiology

Kurahashi K, Sawa T, Ota M, Kajikawa O, Hong K, Martin TR, Wiener-Kronish JP

Novel strategies to combat bacterial virulence.

Current opinion in critical care

Lynch SV, Wiener-Kronish JP

Ventilator-associated pneumonia: problems with diagnosis and therapy.

Best practice & research. Clinical anaesthesiology

Wiener-Kronish JP, Dorr HI

Increased mortality of ventilated patients with endotracheal Pseudomonas aeruginosa without clinical signs of infection.

Critical care medicine

Zhuo H, Yang K, Lynch SV, Dotson RH, Glidden DV, Singh G, Webb WR, Elicker BM, Garcia O, Brown R, Sawa Y, Misset B, Wiener-Kronish JP

Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability.

American journal of respiratory cell and molecular biology

Ganter MT, Roux J, Su G, Lynch SV, Deutschman CS, Weiss YG, Christiaans SC, Myazawa B, Kipnis E, Wiener-Kronish JP, Howard M, Pittet JF

Proteomic analysis of undiluted lung epithelial lining fluid.

Chest

Kipnis E, Hansen K, Sawa T, Moriyama K, Zurawel A, Ishizaka A, Wiener-Kronish J

Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia.

American journal of respiratory and critical care medicine

El Solh AA, Akinnusi ME, Wiener-Kronish JP, Lynch SV, Pineda LA, Szarpa K

Role of integrin alphav beta6 in acute lung injury induced by Pseudomonas aeruginosa.

Infection and immunity

Song Y, Pittet JF, Huang X, He H, Lynch SV, Violette SM, Weinreb PH, Horan GS, Carmago A, Sawa Y, Bernstein XL, Wiener-Kronish JP

Transient hyperglycemia affects the extent of ischemia-reperfusion-induced renal injury in rats.

Anesthesiology

Hirose R, Xu F, Dang K, Liu T, Behrends M, Brakeman PR, Wiener-Kronish J, Niemann CU

The epithelium in acute lung injury/acute respiratory distress syndrome.

Current opinion in critical care

Gropper MA, Wiener-Kronish J

Comparison of type III secretion system virulence among fluoroquinolone-susceptible and -resistant clinical isolates of Pseudomonas aeruginosa.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Wong-Beringer A, Wiener-Kronish J, Lynch S, Flanagan J

Treating lung infections with anticoagulation: mechanisms matter.

Critical care medicine

Pittet JF, Song Y, Wiener-Kronish JP

2007 in review: a dozen steps forward in Anesthesiology.

Anesthesiology

Eisenach JC, Borgeat A, Bosnjak ZJ, Brennan TJ, Kersten JR, Kochs EF, Wiener-Kronish JP

Loss of bacterial diversity during antibiotic treatment of intubated patients colonized with Pseudomonas aeruginosa.

Journal of clinical microbiology

Flanagan JL, Brodie EL, Weng L, Lynch SV, Garcia O, Brown R, Hugenholtz P, DeSantis TZ, Andersen GL, Wiener-Kronish JP, Bristow J

Effect of anti-PcrV antibody in a murine chronic airway Pseudomonas aeruginosa infection model.

The European respiratory journal

Imamura Y, Yanagihara K, Fukuda Y, Kaneko Y, Seki M, Izumikawa K, Miyazaki Y, Hirakata Y, Sawa T, Wiener-Kronish JP, Kohno S

Increased plasminogen activator inhibitor-1 concentrations in bronchoalveolar lavage fluids are associated with increased mortality in a cohort of patients with Pseudomonas aeruginosa.

Anesthesiology

Song Y, Lynch SV, Flanagan J, Zhuo H, Tom W, Dotson RH, Baek MS, Rubio-Mills A, Singh G, Kipnis E, Glidden D, Brown R, Garcia O, Wiener-Kronish JP

Alveolar hemostasis in patients with species-specific bacterial-mediated ventilator-associated pneumonia.

Critical care medicine

Song Y, Wiener-Kronish JP, Flanagan J, Lynch SV

Presence or absence of lipopolysaccharide O antigens affects type III secretion by Pseudomonas aeruginosa.

Journal of bacteriology

Augustin DK, Song Y, Baek MS, Sawa Y, Singh G, Taylor B, Rubio-Mills A, Flanagan JL, Wiener-Kronish JP, Lynch SV

Cell signaling underlying the pathophysiology of pneumonia.

American journal of physiology. Lung cellular and molecular physiology

Prince AS, Mizgerd JP, Wiener-Kronish J, Bhattacharya J

Surfactant proteins A and D enhance pulmonary clearance of Pseudomonas aeruginosa.

American journal of respiratory cell and molecular biology

Giannoni E, Sawa T, Allen L, Wiener-Kronish J, Hawgood S

Targeting mechanisms of Pseudomonas aeruginosa pathogenesis.

Me´decine et maladies infectieuses

Kipnis E, Sawa T, Wiener-Kronish J

Passive anti-PcrV treatment protects burned mice against Pseudomonas aeruginosa challenge.

Burns : journal of the International Society for Burn Injuries

Neely AN, Holder IA, Wiener-Kronish JP, Sawa T

Pseudomonas aeruginosa causes acute lung injury via the catalytic activity of the patatin-like phospholipase domain of ExoU.

Critical care medicine

Pankhaniya RR, Tamura M, Allmond LR, Moriyama K, Ajayi T, Wiener-Kronish JP, Sawa T

V-antigen genotype and phenotype analyses of clinical isolates of Pseudomonas aeruginosa.

Journal of clinical microbiology

Allmond LR, Ajayi T, Moriyama K, Wiener-Kronish JP, Sawa T

Lysophospholipase A activity of Pseudomonas aeruginosa type III secretory toxin ExoU.

Biochemical and biophysical research communications

Tamura M, Ajayi T, Allmond LR, Moriyama K, Wiener-Kronish JP, Sawa T

TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins.

Respiratory research

Faure K, Sawa T, Ajayi T, Fujimoto J, Moriyama K, Shime N, Wiener-Kronish JP

Perioperative anesthesia issues in the elderly.

Critical care clinics

Liu LL, Wiener-Kronish JP

Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model.

Journal of immune based therapies and vaccines

Faure K, Fujimoto J, Shimabukuro DW, Ajayi T, Shime N, Moriyama K, Spack EG, Wiener-Kronish JP, Sawa T

CXC chemokines and their receptors are expressed in type II cells and upregulated following lung injury.

American journal of respiratory cell and molecular biology

Vanderbilt JN, Mager EM, Allen L, Sawa T, Wiener-Kronish J, Gonzalez R, Dobbs LG

The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU.

The EMBO journal

Sato H, Frank DW, Hillard CJ, Feix JB, Pankhaniya RR, Moriyama K, Finck-Barbançon V, Buchaklian A, Lei M, Long RM, Wiener-Kronish J, Sawa T

O-antigen serotypes and type III secretory toxins in clinical isolates of Pseudomonas aeruginosa.

Journal of clinical microbiology

Faure K, Shimabukuro D, Ajayi T, Allmond LR, Sawa T, Wiener-Kronish JP

Predicting mortality in acute respiratory distress syndrome: circulatory system knows best.

Critical care medicine

Misset B, Gropper MA, Wiener-Kronish JP

Development of a high throughput Pseudomonas aeruginosa epithelial cell adhesion assay.

Journal of microbiological methods

Swanson B, Savel R, Szoka F, Sawa T, Wiener-Kronish J

The alveolar epithelium: suspect or innocent bystander?

Anesthesiology

Gropper MA, Wiener-Kronish J

Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV.

The Journal of infectious diseases

Frank DW, Vallis A, Wiener-Kronish JP, Roy-Burman A, Spack EG, Mullaney BP, Megdoud M, Marks JD, Fritz R, Sawa T

Effects of Cl2MDP-encapsulating liposomes in a murine model of Pseudomonas aeruginosa-induced sepsis.

Journal of liposome research

Fujimoto J, Wiener-Kronish JP, Hashimoto S, Sawa T

Aerosolization of lipoplexes using AERx Pulmonary Delivery System.

AAPS pharmSci

Deshpande D, Blanchard J, Srinivasan S, Fairbanks D, Fujimoto J, Sawa T, Wiener-Kronish J, Schreier H, Gonda I

Therapeutic administration of anti-PcrV F(ab')(2) in sepsis associated with Pseudomonas aeruginosa.

Journal of immunology (Baltimore, Md. : 1950)

Shime N, Sawa T, Fujimoto J, Faure K, Allmond LR, Karaca T, Swanson BL, Spack EG, Wiener-Kronish JP

A randomized, controlled trial of advanced care planning discussions during preoperative evaluations.

Anesthesiology

Grimaldo DA, Wiener-Kronish JP, Jurson T, Shaughnessy TE, Curtis JR, Liu LL

Expression of DeltaF508 CFTR in normal mouse lung after site-specific modification of CFTR sequences by SFHR.

Gene therapy

Goncz KK, Colosimo A, Dallapiccola B, Gagné L, Hong K, Novelli G, Papahadjopoulos D, Sawa T, Schreier H, Wiener-Kronish J, Xu Z, Gruenert DC

Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections.

The Journal of infectious diseases

Roy-Burman A, Savel RH, Racine S, Swanson BL, Revadigar NS, Fujimoto J, Sawa T, Frank DW, Wiener-Kronish JP

Effects of antibiotic therapy on Pseudomonas aeruginosa-induced lung injury in a rat model.

Antimicrobial agents and chemotherapy

Ernst EJ, Hashimoto S, Guglielmo J, Sawa T, Pittet JF, Kropp H, Jackson JJ, Wiener-Kronish JP

Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia.

The Journal of clinical investigation

Kurahashi K, Kajikawa O, Sawa T, Ohara M, Gropper MA, Frank DW, Martin TR, Wiener-Kronish JP

The effects of two antiinflammatory pretreatments on bacterial-induced lung injury.

Anesthesiology

Miyazaki H, Broaddus VC, Wiener-Kronish JP, Sawa T, Pittet JF, Kravchenko V, Mathison JC, Nishizawa H, Hattori S, Yamakawa T, Yamada H, Kudoh I

Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury.

Nature medicine

Sawa T, Yahr TL, Ohara M, Kurahashi K, Gropper MA, Wiener-Kronish JP, Frank DW

Evaluation of antimicrobial and lipopolysaccharide-neutralizing effects of a synthetic CAP18 fragment against Pseudomonas aeruginosa in a mouse model.

Antimicrobial agents and chemotherapy

Sawa T, Kurahashi K, Ohara M, Gropper MA, Doshi V, Larrick JW, Wiener-Kronish JP

In vitro cellular toxicity predicts Pseudomonas aeruginosa virulence in lung infections.

Infection and immunity

Sawa T, Ohara M, Kurahashi K, Twining SS, Frank DW, Doroques DB, Long T, Gropper MA, Wiener-Kronish JP

Role of alveolar macrophages in initiation and regulation of inflammation in Pseudomonas aeruginosa pneumonia.

Infection and immunity

Kooguchi K, Hashimoto S, Kobayashi A, Kitamura Y, Kudoh I, Wiener-Kronish J, Sawa T

Halogenated anesthetics and the injured lung: clouds on the horizon?

Anesthesiology

Wiener-Kronish JP, Gropper MA

Preoperative cardiac evaluation of women for noncardiac surgery.

Cardiology clinics

Liu LL, Wiener-Kronish JP

Endothelial exposure to Pseudomonas aeruginosa proteases increases the vulnerability of the alveolar epithelium to a second injury.

American journal of respiratory cell and molecular biology

Pittet JF, Kudoh I, Wiener-Kronish JP

Biochemical detection of type I cell damage after nitrogen dioxide-induced lung injury in rats.

The American journal of physiology

McElroy MC, Pittet JF, Allen L, Wiener-Kronish JP, Dobbs LG

IL-10 improves lung injury and survival in Pseudomonas aeruginosa pneumonia.

Journal of immunology (Baltimore, Md. : 1950)

Sawa T, Corry DB, Gropper MA, Ohara M, Kurahashi K, Wiener-Kronish JP

Efficient in vivo delivery of DNA to pulmonary cells using the novel lipid EDMPC.

Gene therapy

Gorman CM, Aikawa M, Fox B, Fox E, Lapuz C, Michaud B, Nguyen H, Roche E, Sawa T, Wiener-Kronish JP

Neutrophil elastase inhibitor, ONO-5046, modulates acid-induced lung and systemic injury in rabbits.

Anesthesiology

Kaneko K, Kudoh I, Hattori S, Yamada H, Ohara M, Wiener-Kronish J, Okumura F

Assessment of operative risk for patients with advanced lung disease.

Clinics in chest medicine

Kheradmand F, Wiener-Kronish JP, Corry DB

ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury.

Molecular microbiology

Finck-Barbançon V, Goranson J, Zhu L, Sawa T, Wiener-Kronish JP, Fleiszig SM, Wu C, Mende-Mueller L, Frank DW

Identification of Pseudomonas aeruginosa genes required for epithelial cell injury.

Molecular microbiology

Kang PJ, Hauser AR, Apodaca G, Fleiszig SM, Wiener-Kronish J, Mostov K, Engel JN

Nitric oxide attenuates lung endothelial injury caused by sublethal hyperoxia in rats.

The American journal of physiology

McElroy MC, Wiener-Kronish JP, Miyazaki H, Sawa T, Modelska K, Dobbs LG, Pittet JF

Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S.

Infection and immunity

Fleiszig SM, Wiener-Kronish JP, Miyazaki H, Vallas V, Mostov KE, Kanada D, Sawa T, Yen TS, Frank DW

Aerosolization of imipenem/cilastatin prevents pseudomonas-induced acute lung injury.

The Journal of antimicrobial chemotherapy

Hashimoto S, Wolfe E, Guglielmo B, Shanks R, Sundelof J, Pittet JF, Thomas E, Wiener-Kronish J

Soluble complement receptor type 1 inhibited the systemic organ injury caused by acid instillation into a lung.

Anesthesiology

Nishizawa H, Yamada H, Miyazaki H, Ohara M, Kaneko K, Yamakawa T, Wiener-Kronish J, Kudoh I

Intraluminal water increases expression of plasmid DNA in rat lung.

Human gene therapy

Sawa T, Miyazaki H, Pittet JF, Widdicombe JH, Gropper MA, Hashimoto S, Conrad DJ, Folkesson HG, Debs R, Forsayeth JR, Fox B, Wiener-Kronish JP

Depletion of alveolar macrophages decreases neutrophil chemotaxis to Pseudomonas airspace infections.

The American journal of physiology

Hashimoto S, Pittet JF, Hong K, Folkesson H, Bagby G, Kobzik L, Frevert C, Watanabe K, Tsurufuji S, Wiener-Kronish J

Exotoxin A stimulates fluid reabsorption from distal airspaces of lung in anesthetized rats.

The American journal of physiology

Pittet JF, Hashimoto S, Pian M, McElroy MC, Nitenberg G, Wiener-Kronish JP

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

The Journal of experimental medicine

Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, Locksley RM

Identification of patients with acute lung injury. Predictors of mortality.

American journal of respiratory and critical care medicine

Doyle RL, Szaflarski N, Modin GW, Wiener-Kronish JP, Matthay MA

Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing.

Infection and immunity

Apodaca G, Bomsel M, Lindstedt R, Engel J, Frank D, Mostov KE, Wiener-Kronish J

Resistance of the alveolar epithelium to injury from septic shock in sheep.

American journal of respiratory and critical care medicine

Pittet JF, Wiener-Kronish JP, Serikov V, Matthay MA

The effect of pentoxifylline on acid-induced alveolar epithelial injury.

Anesthesiology

Kudoh I, Ohtake M, Nishizawa H, Kurahashi K, Hattori S, Okumura F, Pittet JF, Wiener-Kronish J

A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia.

The American journal of physiology

McElroy MC, Pittet JF, Hashimoto S, Allen L, Wiener-Kronish JP, Dobbs LG

Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury.

The American journal of physiology

Kudoh I, Wiener-Kronish JP, Hashimoto S, Pittet JF, Frank D

Acute cardiogenic pulmonary edema.

Clinics in chest medicine

Gropper MA, Wiener-Kronish JP, Hashimoto S

Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats.

The Journal of clinical investigation

Pittet JF, Wiener-Kronish JP, McElroy MC, Folkesson HG, Matthay MA

Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro.

The Journal of clinical investigation

Massion PP, Inoue H, Richman-Eisenstat J, Grunberger D, Jorens PG, Housset B, Pittet JF, Wiener-Kronish JP, Nadel JA

Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits.

Journal of applied physiology (Bethesda, Md. : 1985)

Wiener-Kronish JP, Sakuma T, Kudoh I, Pittet JF, Frank D, Dobbs L, Vasil ML, Matthay MA

Neutrophil-activating peptide-2 in patients with pulmonary edema from congestive heart failure or ARDS.

The American journal of physiology

Cohen AB, Stevens MD, Miller EJ, Atkinson MA, Mullenbach G, Maunder RJ, Martin TR, Wiener-Kronish JP, Matthay MA

Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock.

Journal of immunology (Baltimore, Md. : 1950)

Newman W, Beall LD, Carson CW, Hunder GG, Graben N, Randhawa ZI, Gopal TV, Wiener-Kronish J, Matthay MA

Interrelationship of pleural and pulmonary interstitial liquid.

Annual review of physiology

Wiener-Kronish JP, Broaddus VC

Monoclonal therapy for bacteremia and sepsis.

The Western journal of medicine

Guglielmo J, Wiener-Kronish JP

Impact of transhiatal esophagectomy on cardiac and respiratory function.

American journal of surgery

Patti MG, Wiener-Kronish JP, Way LW, Pellegrini CA

Differential responses of the endothelial and epithelial barriers of the lung in sheep to Escherichia coli endotoxin.

The Journal of clinical investigation

Wiener-Kronish JP, Albertine KH, Matthay MA

Management of the difficult airway.

Clinics in chest medicine

Schwartz DE, Wiener-Kronish JP

No evidence for mesothelial cell contact across the costal pleural space of sheep.

Journal of applied physiology (Bethesda, Md. : 1985)

Albertine KH, Wiener-Kronish JP, Bastacky J, Staub NC

Intact epithelial barrier function is critical for the resolution of alveolar edema in humans.

The American review of respiratory disease

Matthay MA, Wiener-Kronish JP

Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome.

The Journal of clinical investigation

Rubin DB, Wiener-Kronish JP, Murray JF, Green DR, Turner J, Luce JM, Montgomery AB, Marks JD, Matthay MA

The adult respiratory distress syndrome: definition and prognosis, pathogenesis and treatment.

British journal of anaesthesia

Wiener-Kronish JP, Gropper MA, Matthay MA

Clearance of lung edema into the pleural space of volume-loaded anesthetized sheep.

Journal of applied physiology (Bethesda, Md. : 1985)

Broaddus VC, Wiener-Kronish JP, Staub NC

Respiratory management after cardiac surgery.

Chest

Matthay MA, Wiener-Kronish JP

Relationship of pleural effusions to increased permeability pulmonary edema in anesthetized sheep.

The Journal of clinical investigation

Wiener-Kronish JP, Broaddus VC, Albertine KH, Gropper MA, Matthay MA, Staub NC

Sulfidopeptide-leukotriene peptidases in pulmonary edema fluid from patients with the adult respiratory distress syndrome.

Journal of clinical immunology

Ratnoff WD, Matthay MA, Wong MY, Ito Y, Vu KH, Wiener-Kronish J, Goetzl EJ

Removal of pleural liquid and protein by lymphatics in awake sheep.

Journal of applied physiology (Bethesda, Md. : 1985)

Broaddus VC, Wiener-Kronish JP, Berthiaume Y, Staub NC

Lack of association of pleural effusion with chronic pulmonary arterial and right atrial hypertension.

Chest

Wiener-Kronish JP, Goldstein R, Matthay RA, Biondi JW, Broaddus VC, Chatterjee K, Matthay MA

Regional differences in pleural lymphatic albumin concentration in sheep.

The American journal of physiology

Albertine KH, Schultz EL, Wiener-Kronish JP, Staub NC

Pathophysiology of the adult respiratory distress syndrome. What have we learned from human studies?

Critical care clinics

Fein A, Wiener-Kronish JP, Niederman M, Matthay MA

Poor correlation between pulmonary arterial wedge pressure and left ventricular end-diastolic volume after coronary artery bypass graft surgery.

Anesthesiology

Hansen RM, Viquerat CE, Matthay MA, Wiener-Kronish JP, DeMarco T, Bahtia S, Marks JD, Botvinick EH, Chatterjee K

Relationship of pleural effusions to pulmonary hemodynamics in patients with congestive heart failure.

The American review of respiratory disease

Wiener-Kronish JP, Matthay MA, Callen PW, Filly RA, Gamsu G, Staub NC

Pleural effusions and pulmonary edema.

Clinics in chest medicine

Wiener-Kronish JP, Berthiaume Y, Albertine KH

Pleural liquid pressure in dogs measured using a rib capsule.

Journal of applied physiology (Bethesda, Md. : 1985)

Wiener-Kronish JP, Gropper MA, Lai-Fook SJ

Undrained bloody pericardial effusion in the early postoperative period after coronary bypass surgery: a prospective blood pool study.

American heart journal

Viquerat CE, Hansen RM, Botvinick EH, Dae MW, Wiener-Kronish JP, Matthay MA

Blood supply of the caudal mediastinal lymph node in sheep.

The Anatomical record

Albertine KH, Wiener-Kronish JP, Staub NC

Quantification of damage by air emboli to lung microvessels in anesthetized sheep.

Journal of applied physiology: respiratory, environmental and exercise physiology

Albertine KH, Wiener-Kronish JP, Koike K, Staub NC

The structure of the parietal pleura and its relationship to pleural liquid dynamics in sheep.

The Anatomical record

Albertine KH, Wiener-Kronish JP, Staub NC

Protein egress and entry rates in pleural fluid and plasma in sheep.

Journal of applied physiology: respiratory, environmental and exercise physiology

Wiener-Kronish JP, Albertine KH, Licko V, Staub NC

Removal of abdominal sources of caudal mediastinal node lymph in anesthetized sheep.

Journal of applied physiology: respiratory, environmental and exercise physiology

Roos PJ, Wiener-Kronish JP, Albertine KH, Staub NC

Overperfusion, hypoxia, and increased pressure cause only hydrostatic pulmonary edema in anesthetized sheep.

Circulation research

Landolt CC, Matthay MA, Albertine KH, Roos PJ, Wiener-Kronish JP, Staub NC

Structure, blood supply, and lymphatic vessels of the sheep's visceral pleura.

The American journal of anatomy

Albertine KH, Wiener-Kronish JP, Roos PJ, Staub NC

Severe pulmonary involvement in mixed connective tissue disease.

The American review of respiratory disease

Wiener-Kronish JP, Solinger AM, Warnock ML, Churg A, Ordonez N, Golden JA

Cushing's disease: growth hormone response to hypoglycemia after correction of hypercortisolism.

The Journal of clinical endocrinology and metabolism

Tyrrell JB, Wiener-Kronish J, Lorenzi M, Brooks RM, Forsham PH