Jeanine Wiener-Kronish, MD | The Center for Health and Community

Armstead V, Bucklin B, Bustillo M, Hastie MJ, Lane-Fall M, Lee A, Leffert L, Mackensen GB, Minhaj M, Sakai T, Straker T, Thenuwara K, Whitlock E, Whittington R, Wiener-Kronish J, Wong C

Standard Sedation and Sedation With Isoflurane in Mechanically Ventilated Patients With Coronavirus Disease 2019.

Critical care explorations

Prevention of Complications in the Cardiac Intensive Care Unit.

Journal of cardiothoracic and vascular anesthesia

Shelton KT, Crowley J, Wiener-Kronish J

Evolving Role of Anesthesiology Intensivists in Cardiothoracic Critical Care.

Anesthesiology

Shelton KT, Wiener-Kronish JP

Controversies in Perioperative Antimicrobial Prophylaxis.

Anesthesiology

Decker BK, Nagrebetsky A, Lipsett PA, Wiener-Kronish JP, O'Grady NP

A lung rescue team improves survival in obesity with acute respiratory distress syndrome.

Critical care (London, England)

Florio G, Ferrari M, Bittner EA, De Santis Santiago R, Pirrone M, Fumagalli J, Teggia Droghi M, Mietto C, Pinciroli R, Berg S, Bagchi A, Shelton K, Kuo A, Lai Y, Sonny A, Lai P, Hibbert K, Kwo J, Pino RM, Wiener-Kronish J, Amato MBP, Arora P, Kacmarek RM, Berra L

Remote Surveillance Technologies: Realizing the Aim of Right Patient, Right Data, Right Time.

Anesthesia and analgesia

Safavi KC, Driscoll W, Wiener-Kronish JP

Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial.

The Lancet. Respiratory medicine

Matthay MA, Calfee CS, Zhuo H, Thompson BT, Wilson JG, Levitt JE, Rogers AJ, Gotts JE, Wiener-Kronish JP, Bajwa EK, Donahoe MP, McVerry BJ, Ortiz LA, Exline M, Christman JW, Abbott J, Delucchi KL, Caballero L, McMillan M, McKenna DH, Liu KD

The Complexity and Challenges of Intensive Care Unit Admissions and Discharges: Similarities With All Hospitalized Patients.

JAMA internal medicine

Safavi K, Wiener-Kronish J, Hanidziar D

Intubation With Video Laryngoscopy vs Direct Laryngoscopy.

JAMA

Saddawi-Konefka D, Baker KH, Wiener-Kronish JP

Ensuring the Future of the Specialty: What Is the Best Strategy to Ensure a Pipeline of Physician-scientists?

Anesthesiology

Fleisher LA, Wiener-Kronish JP

New investigations of core competencies: perioperative mechanical ventilation and assessment of lung function.

Anesthesiology

Wiener-Kronish JP, Vidal Melo MF

Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial.

The Lancet. Respiratory medicine

Wilson JG, Liu KD, Zhuo H, Caballero L, McMillan M, Fang X, Cosgrove K, Vojnik R, Calfee CS, Lee JW, Rogers AJ, Levitt J, Wiener-Kronish J, Bajwa EK, Leavitt A, McKenna D, Thompson BT, Matthay MA

Association between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: a review.

Critical care (London, England)

Sawa T, Shimizu M, Moriyama K, Wiener-Kronish JP

Research at the Harvard Anesthesia Departments.

Anesthesiology

Forman SA, Miller KW, Talmor D, Hickey P, Strichartz G, Wiener-Kronish J

Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome.

Annals of intensive care

Liu KD, Wilson JG, Zhuo H, Caballero L, McMillan ML, Fang X, Cosgrove K, Calfee CS, Lee JW, Kangelaris KN, Gotts JE, Rogers AJ, Levitt JE, Wiener-Kronish JP, Delucchi KL, Leavitt AD, McKenna DH, Thompson BT, Matthay MA

Blood transfusions and infected lungs--worse outcomes?*.

Critical care medicine

Wiener-Kronish J, Nozari A

Telemedicine in the intensive care unit: effect of a remote intensivist on outcomes.

JAMA internal medicine

Wilcox ME, Wiener-Kronish JP

In reply.

Anesthesiology

Fleisher LA, Evers AS, Wiener-Kronish J, Ulatowski JA

What are we looking for? The question of resident selection.

Anesthesiology

Fleisher LA, Evers AS, Wiener-Kronish J, Ulatowski JA

Continuing aspirin in the perioperative patient.

Annals of surgery

Connors JM, Wiener-Kronish JP

Treating bacterial virulence systems: we are not there yet.

Intensive care medicine

Huang YJ, Bittner EA, Frank D, Wiener-Kronish J

From microbe to microbiota: considering microbial community composition in infections and airway diseases.

American journal of respiratory and critical care medicine

Huang YJ, Lynch SV, Wiener-Kronish JP

Is the evidence for benefits from ventilator-associated pneumonia bundles reliable enough for implementation in a general hospital?

Critical care medicine

Kalil AC, Wiener-Kronish JP

Strain-dependent induction of neutrophil histamine production and cell death by Pseudomonas aeruginosa.

Journal of leukocyte biology

Xu X, Zhang H, Song Y, Lynch SV, Lowell CA, Wiener-Kronish JP, Caughey GH

Therapies against virulence products of Staphylococcus aureus and Pseudomonas aeruginosa.

Seminars in respiratory and critical care medicine

Wiener-Kronish JP, Pittet JF

Newer technology is not always better.

Critical care medicine

Albrecht M, Wiener-Kronish JP

Plasminogen activation inhibitor concentrations in bronchoalveolar lavage fluid distinguishes ventilator-associated pneumonia from colonization in mechanically ventilated pediatric patients.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

Srinivasan R, Song Y, Wiener-Kronish J, Flori HR

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma.

The Journal of allergy and clinical immunology

Huang YJ, Nelson CE, Brodie EL, Desantis TZ, Baek MS, Liu J, Woyke T, Allgaier M, Bristow J, Wiener-Kronish JP, Sutherland ER, King TS, Icitovic N, Martin RJ, Calhoun WJ, Castro M, Denlinger LC, Dimango E, Kraft M, Peters SP, Wasserman SI, Wechsler ME, Boushey HA, Lynch SV

Methicillin-resistant Staphylococcus aureus colonization, its relationship to nosocomial infection, and efficacy of control methods.

Anesthesiology

Butterly A, Schmidt U, Wiener-Kronish J

Joseph Adrian Jeevendra Martyn, M.D., F.R.C.A., F.C.C.M., recipient of the 2010 Excellence in Research Award.

Anesthesiology

Wiener-Kronish JP

1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit.

The Journal of trauma

Cohen MJ, Serkova NJ, Wiener-Kronish J, Pittet JF, Niemann CU

Polymorphisms in the Pseudomonas aeruginosa type III secretion protein, PcrV - implications for anti-PcrV immunotherapy.

Microbial pathogenesis

Lynch SV, Flanagan JL, Sawa T, Fang A, Baek MS, Rubio-Mills A, Ajayi T, Yanagihara K, Hirakata Y, Kohno S, Misset B, Nguyen JC, Wiener-Kronish JP

A persistent and diverse airway microbiota present during chronic obstructive pulmonary disease exacerbations.

Omics : a journal of integrative biology

Huang YJ, Kim E, Cox MJ, Brodie EL, Brown R, Wiener-Kronish JP, Lynch SV

Effect of ventilator-induced lung injury on skeletal muscle oxidative balance.

Anesthesiology

Musch G, Wiener-Kronish JP

Mechanisms of bacterial virulence in pulmonary infections.

Current opinion in critical care

Moskowitz SM, Wiener-Kronish JP

Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia.

The Journal of trauma

Cohen MJ, Bir N, Rahn P, Dotson R, Brohi K, Chesebro BB, Mackersie R, Carles M, Wiener-Kronish J, Pittet JF

Protective effects of affinity-purified antibody and truncated vaccines against Pseudomonas aeruginosa V-antigen in neutropenic mice.

Microbiology and immunology

Moriyama K, Wiener-Kronish JP, Sawa T

The United States critical illness and injury trials group: an introduction.

The Journal of trauma

Cobb JP, Cairns CB, Bulger E, Wong HR, Parsons PE, Angus DC, Gentile NT, Hoyt DB, Schwinn DA, Wiener-Kronish JP, Upperman JS

Training the next generation of research mentors: the University of California, San Francisco, Clinical & Translational Science Institute Mentor Development Program.

Clinical and translational science

Feldman MD, Huang L, Guglielmo BJ, Jordan R, Kahn J, Creasman JM, Wiener-Kronish JP, Lee KA, Tehrani A, Yaffe K, Brown JS

Matrix metalloproteases in bronchoalveolar lavage fluid of patients with type III Pseudomonas aeruginosa pneumonia.

The Journal of infection

El-Solh AA, Amsterdam D, Alhajhusain A, Akinnusi ME, Saliba RG, Lynch SV, Wiener-Kronish JP

4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumonia.

Anesthesiology

Sapru A, Hansen H, Ajayi T, Brown R, Garcia O, Zhuo H, Wiemels J, Matthay MA, Wiener-Kronish J

An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity.

Infection and immunity

Baer M, Sawa T, Flynn P, Luehrsen K, Martinez D, Wiener-Kronish JP, Yarranton G, Bebbington C

2008 in review: advancing medicine in anesthesiology.

Anesthesiology

Eisenach JC, Borgeat A, Bosnjak ZJ, Brennan TJ, Kersten JR, Kochs E, Lerman J, Warner DS, Wiener-Kronish JP

Multidrug-resistant Pseudomonas aeruginosa ventilator-associated pneumonia: the role of endotracheal aspirate surveillance cultures.

The Annals of pharmacotherapy

Yang K, Zhuo H, Guglielmo BJ, Wiener-Kronish J

Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia.

American journal of physiology. Lung cellular and molecular physiology

Kurahashi K, Sawa T, Ota M, Kajikawa O, Hong K, Martin TR, Wiener-Kronish JP

Novel strategies to combat bacterial virulence.

Current opinion in critical care

Lynch SV, Wiener-Kronish JP

Increased mortality of ventilated patients with endotracheal Pseudomonas aeruginosa without clinical signs of infection.

Critical care medicine

Zhuo H, Yang K, Lynch SV, Dotson RH, Glidden DV, Singh G, Webb WR, Elicker BM, Garcia O, Brown R, Sawa Y, Misset B, Wiener-Kronish JP

Ventilator-associated pneumonia: problems with diagnosis and therapy.

Best practice & research. Clinical anaesthesiology

Wiener-Kronish JP, Dorr HI

Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability.

American journal of respiratory cell and molecular biology

Ganter MT, Roux J, Su G, Lynch SV, Deutschman CS, Weiss YG, Christiaans SC, Myazawa B, Kipnis E, Wiener-Kronish JP, Howard M, Pittet JF

Proteomic analysis of undiluted lung epithelial lining fluid.

Chest

Kipnis E, Hansen K, Sawa T, Moriyama K, Zurawel A, Ishizaka A, Wiener-Kronish J

Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia.

American journal of respiratory and critical care medicine

El Solh AA, Akinnusi ME, Wiener-Kronish JP, Lynch SV, Pineda LA, Szarpa K

Role of integrin alphav beta6 in acute lung injury induced by Pseudomonas aeruginosa.

Infection and immunity

Song Y, Pittet JF, Huang X, He H, Lynch SV, Violette SM, Weinreb PH, Horan GS, Carmago A, Sawa Y, Bernstein XL, Wiener-Kronish JP

Transient hyperglycemia affects the extent of ischemia-reperfusion-induced renal injury in rats.

Anesthesiology

Hirose R, Xu F, Dang K, Liu T, Behrends M, Brakeman PR, Wiener-Kronish J, Niemann CU

The epithelium in acute lung injury/acute respiratory distress syndrome.

Current opinion in critical care

Gropper MA, Wiener-Kronish J

2007 in review: a dozen steps forward in Anesthesiology.

Anesthesiology

Eisenach JC, Borgeat A, Bosnjak ZJ, Brennan TJ, Kersten JR, Kochs EF, Wiener-Kronish JP

Treating lung infections with anticoagulation: mechanisms matter.

Critical care medicine

Pittet JF, Song Y, Wiener-Kronish JP

Promises and limitations of the bronchoscopic microsampling probe.

Chest

Kipnis E, Guery B, Wiener-Kronish J

Alveolar hemostasis in patients with species-specific bacterial-mediated ventilator-associated pneumonia.

Critical care medicine

Song Y, Wiener-Kronish JP, Flanagan J, Lynch SV

Increased plasminogen activator inhibitor-1 concentrations in bronchoalveolar lavage fluids are associated with increased mortality in a cohort of patients with Pseudomonas aeruginosa.

Anesthesiology

Song Y, Lynch SV, Flanagan J, Zhuo H, Tom W, Dotson RH, Baek MS, Rubio-Mills A, Singh G, Kipnis E, Glidden D, Brown R, Garcia O, Wiener-Kronish JP

Beta-2-agonist treatment as a potential therapy for acute inhalational lung injury.

Critical care medicine

Wiener-Kronish JP, Matthay MA

Cell signaling underlying the pathophysiology of pneumonia.

American journal of physiology. Lung cellular and molecular physiology

Prince AS, Mizgerd JP, Wiener-Kronish J, Bhattacharya J

Surfactant proteins A and D enhance pulmonary clearance of Pseudomonas aeruginosa.

American journal of respiratory cell and molecular biology

Giannoni E, Sawa T, Allen L, Wiener-Kronish J, Hawgood S

Endotracheal tubes: the conduit for oral and nasal microbial communities to the lungs.

Anesthesiology

Jacobs R, Wiener-Kronish J

Passive anti-PcrV treatment protects burned mice against Pseudomonas aeruginosa challenge.

Burns : journal of the International Society for Burn Injuries

Neely AN, Holder IA, Wiener-Kronish JP, Sawa T

Pseudomonas aeruginosa causes acute lung injury via the catalytic activity of the patatin-like phospholipase domain of ExoU.

Critical care medicine

Pankhaniya RR, Tamura M, Allmond LR, Moriyama K, Ajayi T, Wiener-Kronish JP, Sawa T

A therapeutic strategy against the shared virulence mechanism utilized by both Yersinia pestis and Pseudomonas aeruginosa.

Anesthesiology clinics of North America

Sawa T, Wiener-Kronish JP

V-antigen genotype and phenotype analyses of clinical isolates of Pseudomonas aeruginosa.

Journal of clinical microbiology

Allmond LR, Ajayi T, Moriyama K, Wiener-Kronish JP, Sawa T

Lysophospholipase A activity of Pseudomonas aeruginosa type III secretory toxin ExoU.

Biochemical and biophysical research communications

Tamura M, Ajayi T, Allmond LR, Moriyama K, Wiener-Kronish JP, Sawa T

TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins.

Respiratory research

Faure K, Sawa T, Ajayi T, Fujimoto J, Moriyama K, Shime N, Wiener-Kronish JP

Perioperative anesthesia issues in the elderly.

Critical care clinics

Liu LL, Wiener-Kronish JP

Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model.

Journal of immune based therapies and vaccines

Faure K, Fujimoto J, Shimabukuro DW, Ajayi T, Shime N, Moriyama K, Spack EG, Wiener-Kronish JP, Sawa T

Single-nucleotide-polymorphism mapping of the Pseudomonas aeruginosa type III secretion toxins for development of a diagnostic multiplex PCR system.

Journal of clinical microbiology

Ajayi T, Allmond LR, Sawa T, Wiener-Kronish JP

CXC chemokines and their receptors are expressed in type II cells and upregulated following lung injury.

American journal of respiratory cell and molecular biology

Vanderbilt JN, Mager EM, Allen L, Sawa T, Wiener-Kronish J, Gonzalez R, Dobbs LG

The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU.

The EMBO journal

Sato H, Frank DW, Hillard CJ, Feix JB, Pankhaniya RR, Moriyama K, Finck-Barbançon V, Buchaklian A, Lei M, Long RM, Wiener-Kronish J, Sawa T

O-antigen serotypes and type III secretory toxins in clinical isolates of Pseudomonas aeruginosa.

Journal of clinical microbiology

Faure K, Shimabukuro D, Ajayi T, Allmond LR, Sawa T, Wiener-Kronish JP

Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system.

Infection and immunity

Allmond LR, Karaca TJ, Nguyen VN, Nguyen T, Wiener-Kronish JP, Sawa T

Publications