Professor Emeritus
M_Neurological Surgery
+1 415 476-9323
Publications
Genetic analysis in African ancestry populations reveals genetic contributors to lung cancer susceptibility.
American journal of human genetics
Dissecting the biology of gliomagenesis: Evaluating the interaction between IDH tumor mutation and germline variants.
Neuro-oncology advances
Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.
Human molecular genetics
Glioma mutational signatures associated with haloalkane exposure are enriched in firefighters.
Cancer
Association of immunoglobulin E levels with glioma risk and survival.
Journal of the National Cancer Institute
Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival.
Nature communications
Methylation cytometric pretreatment blood immune profiles with tumor mutation burden as prognostic indicators for survival outcomes in head and neck cancer patients on anti-PD-1 therapy.
NPJ precision oncology
Glioma immune microenvironment composition calculator (GIMiCC): a method of estimating the proportions of eighteen cell types from DNA methylation microarray data.
Acta neuropathologica communications
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide.
medRxiv : the preprint server for health sciences
Association of immunoglobulin E levels with glioma risk and survival.
medRxiv : the preprint server for health sciences
Oligodendroglioma patient survival is associated with circulating B-cells and age.
Neuro-oncology advances
Maternal prenatal use of alcohol, tobacco, and illicit drugs and associations with childhood cancer subtypes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Matched analysis of detailed peripheral blood and tumor immune microenvironment profiles in bladder cancer.
Epigenomics
Genome-wide Polygenic Risk Scores Predict Risk of Glioma and Molecular Subtypes.
medRxiv : the preprint server for health sciences
Enrichment of a neutrophil-like monocyte transcriptional state in glioblastoma myeloid suppressor cells.
Research square
Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival.
medRxiv : the preprint server for health sciences
Genome-scale methylation analysis identifies immune profiles and age acceleration associations with bladder cancer outcomes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Hierarchical deconvolution for extensive cell type resolution in the human brain using DNA methylation.
Frontiers in neuroscience
Antibodies to varicella-zoster virus and three other herpesviruses and survival in adults with glioma.
Neuro-oncology
Assessment of immune cell profiles among post-menopausal women in the Women's Health Initiative using DNA methylation-based methods.
Clinical epigenetics
Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Comparative analysis of the DNA methylation landscape in CD4, CD8, and B memory lineages.
Clinical epigenetics
HiTIMED: hierarchical tumor immune microenvironment epigenetic deconvolution for accurate cell type resolution in the tumor microenvironment using tumor-type-specific DNA methylation data.
Journal of translational medicine
Evaluation of cross-platform compatibility of a DNA methylation-based glucocorticoid response biomarker.
Clinical epigenetics
A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation.
Science (New York, N.Y.)
DNA methylation as a pharmacodynamic marker of glucocorticoid response and glioma survival.
Nature communications
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer.
Nature genetics
Pre-surgery immune profiles of adult glioma patients.
Journal of neuro-oncology
The immunogenetics of viral antigen response is associated with subtype-specific glioma risk and survival.
American journal of human genetics
Interactions of Age and Blood Immune Factors and Non-Invasive Prediction of Glioma Survival.
Journal of the National Cancer Institute
A core of differentially methylated CpG loci in gMDSCs isolated from neonatal and adult sources.
Clinical epigenetics
Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling.
Nature communications
Immune profiles and DNA methylation alterations related with non-muscle-invasive bladder cancer outcomes.
Clinical epigenetics
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
American journal of human genetics
Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C.
Neuro-oncology
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.
Nature communications
Could Methylation Cytometry Be a Predictive Biomarker of Breast Cancer?
JAMA network open
Immune factors preceding diagnosis of glioma: a Prostate Lung Colorectal Ovarian Cancer Screening Trial nested case-control study.
Neuro-oncology advances
Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data.
Clinical epigenetics
Genetic and molecular epidemiology of adult diffuse glioma.
Nature reviews. Neurology
Glioma risk associated with extent of estimated European genetic ancestry in African-Americans and Hispanics.
International journal of cancer
Cross-Cancer Pleiotropic Associations with Lung Cancer Risk in African Americans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
International journal of cancer
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.
Scientific reports
Immunomethylomics: A Novel Cancer Risk Prediction Tool.
Annals of the American Thoracic Society
Germline polymorphisms in myeloid-associated genes are not associated with survival in glioma patients.
Journal of neuro-oncology
Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma.
Journal of neuro-oncology
Germline Genetic Variants and Lung Cancer Survival in African Americans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
JAMA oncology
Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT.
Acta neuropathologica
Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival.
Clinical epigenetics
DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio: An Epigenetic Tool to Explore Cancer Inflammation and Outcomes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.
Nature communications
Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.
Lung cancer (Amsterdam, Netherlands)
Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL).
BMC bioinformatics
Understanding the Role of the Immune System in the Development of Cancer: New Opportunities for Population-Based Research.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Understanding inherited genetic risk of adult glioma - a review.
Neuro-oncology practice
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.
The New England journal of medicine
DNA Methylation in Whole Blood: Uses and Challenges.
Current environmental health reports
Telomere maintenance and the etiology of adult glioma.
Neuro-oncology
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Science (New York, N.Y.)
CDKN2A loss is associated with shortened overall survival in lower-grade (World Health Organization Grades II-III) astrocytomas.
Journal of neuropathology and experimental neurology
CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.
Journal of the National Cancer Institute
Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective.
BMC bioinformatics
Characterization of large structural genetic mosaicism in human autosomes.
American journal of human genetics
Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures.
Nucleic acids research
Serum macrophage-derived chemokine/CCL22 levels are associated with glioma risk, CD4 T cell lymphopenia and survival time.
International journal of cancer
Survival and low-grade glioma: the emergence of genetic information.
Neurosurgical focus
Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture.
American journal of human genetics
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.
Human molecular genetics
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
Nature genetics
Leukocyte-adjusted epigenome-wide association studies of blood from solid tumor patients.
Epigenetics
PTPRG inhibition by DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia.
International journal of cancer
Interaction of allergy history and antibodies to specific varicella-zoster virus proteins on glioma risk.
International journal of cancer
Socioeconomic status and lung cancer: unraveling the contribution of genetic admixture.
American journal of public health
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Nature genetics
Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies.
Genetic epidemiology
Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network.
Nucleic acids research
Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach.
Frontiers in genetics
Decreased NK cells in patients with head and neck cancer determined in archival DNA.
Clinical cancer research : an official journal of the American Association for Cancer Research
Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium.
American journal of epidemiology
Cigarette smoking associated with lung adenocarcinoma in situ in a large case-control study (SFBALCS).
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.
Nature genetics
Genome-wide association study of glioma and meta-analysis.
Human genetics
Vitamin D receptor polymorphisms and breast cancer risk in a high-incidence population: a pilot study.
Journal of the American College of Surgeons
Fetal growth and body size genes and risk of childhood acute lymphoblastic leukemia.
Cancer causes & control : CCC
PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
Neuro-oncology
Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia.
Cancer causes & control : CCC
DNA methylation arrays as surrogate measures of cell mixture distribution.
BMC bioinformatics
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.
Genetic epidemiology
SSBP2 variants are associated with survival in glioblastoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research
Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium.
European journal of cancer (Oxford, England : 1990)
Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium.
Carcinogenesis
Haplotypes of DNA repair and cell cycle control genes, X-ray exposure, and risk of childhood acute lymphoblastic leukemia.
Cancer causes & control : CCC
Matching on Race and Ethnicity in Case-Control Studies as a Means of Control for Population Stratification.
Epidemiology (Sunnyvale, Calif.)
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.
Nature genetics
Risk of squamous cell carcinoma of the skin in relation to IgE: a nested case-control study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
A case-control study of asphalt and tar exposure and lung cancer in minorities.
American journal of industrial medicine
Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia.
Cancer causes & control : CCC
Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking.
American journal of epidemiology
DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression.
Neuro-oncology
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma.
Journal of the National Cancer Institute
DNA methylation profiles delineate etiologic heterogeneity and clinically important subgroups of bladder cancer.
Carcinogenesis
CD8+ T-cell infiltrate in newly diagnosed glioblastoma is associated with long-term survival.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Circulating levels of the innate and humoral immune regulators CD14 and CD23 are associated with adult glioma.
Cancer research
Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia.
Blood cells, molecules & diseases
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake.
PLoS genetics
Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.
Human molecular genetics
Integrated profiling reveals a global correlation between epigenetic and genetic alterations in mesothelioma.
Cancer research
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.
Journal of the National Cancer Institute
Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Chemokine polymorphisms and lymphoma: a pooled analysis.
Leukemia & lymphoma
KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands)
Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival.
Journal of neuro-oncology
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.
PLoS genetics
IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era.
International journal of cancer
Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles.
Cancer research
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
Nature genetics
Copy number variation has little impact on bead-array-based measures of DNA methylation.
Bioinformatics (Oxford, England)
Associations between polymorphisms in DNA repair genes and glioblastoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.
Cancer research
Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma.
Carcinogenesis
Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome.
Cancer research
Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-Americans.
Carcinogenesis
SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system.
Nucleic acids research
International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African Americans.
International journal of cancer
Comparison of statistical methods for estimating genetic admixture in a lung cancer study of African Americans and Latinos.
American journal of epidemiology
Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions.
BMC bioinformatics
Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California.
Cancer causes & control : CCC
DNA repair polymorphisms XRCC1 and MGMT and risk of adult gliomas.
Neuroepidemiology
DNA quantification of whole genome amplified samples for genotyping on a multiplexed bead array platform.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Allergy-related polymorphisms influence glioma status and serum IgE levels.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma.
Neuro-oncology
DNA adducts in granulocytes of hospital workers exposed to ethylene oxide.
American journal of industrial medicine
Lower specific micronutrient intake in colorectal cancer patients with tumors presenting promoter hypermethylation in p16(INK4a), p4(ARF) and hMLH1.
Anticancer research
Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and T1, and metabolism of arsenic.
Journal of toxicology and environmental health. Part A
Nonsynonymous coding single-nucleotide polymorphisms spanning the genome in relation to glioblastoma survival and age at diagnosis.
Clinical cancer research : an official journal of the American Association for Cancer Research
DNA adducts among asphalt paving workers.
The Annals of occupational hygiene
Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival.
Cancer research
Homozygous deletion of p16INK4a and tobacco carcinogen exposure in nonsmall cell lung cancer.
International journal of cancer
The case for strategic international alliances to harness nutritional genomics for public and personal health.
The British journal of nutrition
Interaction between the bone morphogenetic proteins and Ras/MAP-kinase signalling pathways in lung cancer.
British journal of cancer
Alterations of 9p in squamous cell carcinoma and adenocarcinoma of the lung: association with smoking, TP53, and survival.
Cancer genetics and cytogenetics
ERCC1 and ERCC2 polymorphisms and adult glioma.
Neuro-oncology
Molecular biomarkers for the study of childhood leukemia.
Toxicology and applied pharmacology
Ethnic difference in daycare attendance, early infections, and risk of childhood acute lymphoblastic leukemia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Molecular features of adult glioma associated with patient race/ethnicity, age, and a polymorphism in O6-methylguanine-DNA-methyltransferase.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration.
Human pathology
Polyphenol associated-DNA adducts in lung and blood mononuclear cells from lung cancer patients.
Cancer letters
The C3435T polymorphism of MDR1 and susceptibility to adult glioma.
Neuroepidemiology
History of chickenpox and shingles and prevalence of antibodies to varicella-zoster virus and three other herpesviruses among adults with glioma and controls.
American journal of epidemiology
The race associated allele of Semaphorin 3B (SEMA3B) T415I and its role in lung cancer in African-Americans and Latino-Americans.
Carcinogenesis
Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence.
International journal of cancer
CYP1A1 variants and smoking-related lung cancer in San Francisco Bay area Latinos and African Americans.
International journal of cancer
Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small-cell lung cancer.
Cancer research
Reduced immunoglobulin E and allergy among adults with glioma compared with controls.
Cancer research
Investigation of genetic polymorphisms and smoking in a bladder cancer case-control study in Argentina.
Cancer letters
Urinary 1-hydroxypyrene and polycyclic aromatic hydrocarbon exposure among asphalt paving workers.
The Annals of occupational hygiene
On the use of biomarkers for environmental health research.
Statistical methods in medical research
Decrease in specific micronutrient intake in colorectal cancer patients with tumors presenting Ki-ras mutation.
Anticancer research
Lack of increased genetic damage in 1,3-butadiene-exposed Chinese workers studied in relation to EPHX1 and GST genotypes.
Mutation research
Glutathione-S-transferase variants and adult glioma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Impact of race/ethnicity on molecular pathways in human cancer.
Nature reviews. Cancer
Population- and community-based recruitment of African Americans and Latinos: the San Francisco Bay Area Lung Cancer Study.
American journal of epidemiology
Cancer, genes, and catechol estrogen metabolites.
International journal of clinical oncology
Teen smoking, field cancerization, and a "critical period" hypothesis for lung cancer susceptibility.
Environmental health perspectives
Daycare attendance and risk of childhood acute lymphoblastic leukaemia.
British journal of cancer
History of allergies among adults with glioma and controls.
International journal of cancer
A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk.
Journal of the National Cancer Institute
Prevalence of antibodies to four herpesviruses among adults with glioma and controls.
American journal of epidemiology
Markers for carcinogenicity among butadiene-polymer workers in China.
Chemico-biological interactions
Whole genome amplification increases the efficiency and validity of buccal cell genotyping in pediatric populations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Hemoglobin adducts and sister chromatid exchanges in hospital workers exposed to ethylene oxide: effects of glutathione S-transferase T1 and M1 genotypes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer.
Cancer research
Associations between ERCC2 polymorphisms and gliomas.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer.
Oncogene
Genetic resistance factor for HIV-1 and immune response to varicella zoster virus.
Lancet (London, England)
NAT2 and NQO1 polymorphisms are not associated with adult glioma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer.
Cancer research
Evaluation of buccal cell collection protocols for genetic susceptibility studies.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
NAD(P)H:quinone oxidoreductase-dependent risk for colorectal cancer and its association with the presence of K-ras mutations in tumors.
Carcinogenesis
The p53 codon 72 polymorphism and lung cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Association of an ERCC1 polymorphism with adult-onset glioma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Chromosomal aberrations and hprt mutant frequencies in long-term American thorotrast survivors.
International journal of radiation biology
Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells.
Carcinogenesis
Lack of association of rare alleles in the HRAS variable number of tandem repeats (VNTR) region with adult glioma.
Neuro-oncology
Negative binomial additive models.
Biometrics
Genotoxic markers among butadiene polymer workers in China.
Carcinogenesis
Implications and prognostic value of K-ras mutation for early-stage lung cancer in women.
Journal of the National Cancer Institute
k-ras mutation and occupational asbestos exposure in lung adenocarcinoma: asbestos-related cancer without asbestosis.
Cancer research
Aberrant methylation of p16INK4a in anatomic and gender-specific subtypes of sporadic colorectal cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Modulation of the toxicity and macromolecular binding of benzene metabolites by NAD(P)H:Quinone oxidoreductase in transfected HL-60 cells.
Chemical research in toxicology
Early age at smoking initiation and tobacco carcinogen DNA damage in the lung.
Journal of the National Cancer Institute
Association between diet and lung cancer location.
American journal of respiratory and critical care medicine
Chromosome 3p14 alterations in lung cancer: evidence that FHIT exon deletion is a target of tobacco carcinogens and asbestos.
Cancer research
Growing pains for the environmental genetics of breast cancer: observations on a study of the glutathione S-transferases.
Journal of the National Cancer Institute
Association of cigarette smoking and asbestos exposure with location and histology of lung cancer.
American journal of respiratory and critical care medicine
Benzene exposure, glutathione S-transferase theta homozygous deletion, and sister chromatid exchanges.
American journal of industrial medicine
Polymorphisms in the N acetyltransferase 1 NAT1 gene and lung cancer risk in a minority population.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
A population-based case-control study of the CYP2D6 and GSTT1 polymorphisms and malignant brain tumors.
Pharmacogenetics
Susceptibility to lung cancer in light smokers associated with CYP1A1 polymorphisms in Mexican- and African-Americans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
A case-control study of cytochrome P450 1A1, glutathione S-transferase M1, cigarette smoking and lung cancer susceptibility (Massachusetts, United States)
Cancer causes & control : CCC
Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States).
Cancer causes & control : CCC
Population-based study of glutathione S-transferase mu gene deletion in adult glioma cases and controls.
Carcinogenesis
Inhibition of poly(ADP-ribose) polymerase by arsenite.
Mutation research
Study of arsenic mutagenesis using the plasmid shuttle vector pZ189 propagated in DNA repair proficient human cells.
Mutation research
Does prior infection with varicella-zoster virus influence risk of adult glioma?
American journal of epidemiology
Familial and personal medical history of cancer and nervous system conditions among adults with glioma and controls.
American journal of epidemiology
The glutathione S-transferase theta and mu deletion polymorphisms in asbestosis.
American journal of industrial medicine
Lung cancer in Mexican-Americans and African-Americans is associated with the wild-type genotype of the NAD(P)H: quinone oxidoreductase polymorphism.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy.
British journal of cancer
Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cytochrome P450 CYP1A1 MspI polymorphism and lung cancer susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung.
Cancer research
Mutant frequency at the hprt locus in human lymphocytes in a case-control study of lung cancer.
Mutation research
Comparison of sister chromatid exchange frequency in peripheral lymphocytes in lung cancer cases and controls.
Mutation research
Glutathione S-transferase mu genotype, diet, and smoking as determinants of sister chromatid exchange frequency in lymphocytes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Mutations in the p53 gene in lung cancer are associated with cigarette smoking and asbestos exposure.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Genotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
Mutation research
Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta.
Carcinogenesis
Gene deletion of glutathione S-transferase theta: correlation with induced genetic damage and potential role in endogenous mutagenesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Inherited glutathione-S-transferase deficiency is a risk factor for pulmonary asbestosis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
A race-specific genetic polymorphism in the CYP1A1 gene is not associated with lung cancer in African Americans.
Carcinogenesis
Genetics of primary brain tumors: a review.
Journal of neuro-oncology
Gross cystic disease fluid protein in nipple aspirates of breast fluid of Asian and non-Asian women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Enhancement of chromosomal damage by arsenic: implications for mechanism.
Environmental health perspectives
Indications of repair of radon-induced chromosome damage in human lymphocytes: an adaptive response induced by low doses of X-rays.
Environmental health perspectives
Environmental risk factors for primary malignant brain tumors: a review.
Journal of neuro-oncology
Glutathione S-transferase mu polymorphism does not explain variation in nitroglycerin responsiveness.
Clinical pharmacology and therapeutics
Susceptibility to induction of chromosomal damage by metabolites of 1,3-butadiene and its relationship to 'spontaneous' sister chromatid exchange frequencies in human lymphocytes.
IARC scientific publications
Heterogeneity in the clastogenic response to X-rays in lymphocytes from ataxia-telangiectasia heterozygotes and controls.
Cancer causes & control : CCC
Specificity of arsenite in potentiating cytogenetic damage induced by the DNA crosslinking agent diepoxybutane.
Environmental and molecular mutagenesis
Individual susceptibility to induced chromosome damage and its implications for detecting genotoxic exposures in human populations.
Cancer research
Adaptive response of human lymphocytes for the repair of radon-induced chromosomal damage.
Mutation research
Bimodal distribution of sensitivity to SCE induction by diepoxybutane in human lymphocytes. I. Correlation with chromosomal aberrations.
Mutation research
Bimodal distribution of sensitivity to SCE induction by diepoxybutane in human lymphocytes. II. Relationship to baseline SCE frequency.
Mutation research
Molecular dosimetry of DNA adducts and sister chromatid exchanges in human lymphocytes treated with benzo[a]pyrene.
Carcinogenesis
Human glutathione S-transferase deficiency as a marker of susceptibility to epoxide-induced cytogenetic damage.
Cancer research
Genetic polymorphisms in carcinogen metabolism predict substrate-induced cytogenetic damage in humans.
Progress in clinical and biological research
Inhibition of the adaptive response of human lymphocytes to very low doses of ionizing radiation by the protein synthesis inhibitor cycloheximide.
Mutation research
Sister chromatid exchange in painters recently exposed to solvents.
Environmental research
Antipain-mediated suppression of X-ray-induced chromosomal aberrations in human lymphocytes.
Carcinogenesis
Induction of the adaptive response by X-rays is dependent on radiation intensity.
International journal of radiation biology
Persistently elevated sister chromatid exchanges in ethylene oxide-exposed primates: the role of a subpopulation of high frequency cells.
Cancer research
Effects of cigarette smoking and solvent exposure on sister chromatid exchange frequency in painters.
Environmental and molecular mutagenesis
Human lymphocytes exposed to low doses of ionizing radiations become refractory to high doses of radiation as well as to chemical mutagens that induce double-strand breaks in DNA.
International journal of radiation biology and related studies in physics, chemistry, and medicine
Nicotinamide deficiency in human lymphocytes prevents the [3H]thymidine-induced adaptive response for the repair of X-ray-induced chromosomal damage.
Experimental cell research
Cell cycle-dependent potentiation of X-ray-induced chromosomal aberrations by 3-aminobenzamide.
Biochemical and biophysical research communications
3-Aminobenzamide does not affect X-ray-induced cytogenetic damage in G0 human lymphocytes.
Mutation research
N-Methyl-N-nitrosourea potentiation of cytogenetic damage induced by 1,3-bis(2-chloroethyl)-1-nitrosourea in normal human lymphocytes.
Cancer research
Ethylene oxide and some factors affecting the mutagen sensitivity of sister chromatid exchange in humans.
Basic life sciences
Serum- and plasma-dependent variations of benzo(a)pyrene-induced sister chromatid exchange in human lymphocytes.
Basic life sciences
Sister-chromatid exchange induction by cis-platinum/adriamycin cancer chemotherapy.
Mutation research
Ethylene oxide induced sister chromatid exchange in human lymphocytes using a membrane dosimetry system.
Pharmacology
Mutagenic activity of anticancer agent cis-dichlorodiammine platinum-II.
Mutation research