Kathryn Phillips, PhD

Professor
Clinical Pharmacy
+1 415 502-8271

Kathryn A. Phillips, PhD, a health services researcher and health economist and leader in the application of new technologies to improve healthcare, is the founding director of the Center for Translational and Policy Research on Personalized Medicine (TRANSPERS) in the School of Pharmacy at the University of California, San Francisco (UCSF). She is also a professor of health economics and health services research in the Department of Clinical Pharmacy at UCSF, with additional appointments in the UCSF Philip R. Lee Institute for Health Policy Studies and UCSF Helen Diller Family Comprehensive Cancer Center

Kathryn focuses on the value of new technologies and how to most effectively and efficiently implement them into health care. Her core specialty is personalized (or precision) medicine — a new era of healthcare where medical interventions can be tailored to individual patients based on their unique genetic make-up. Her work spans multiple disciplines, including basic, clinical and social sciences, and brings together leading experts in academia, industry, healthcare, payers, and government. Kathryn led one of the earliest studies on the societal implications of pharmacogenomics, underscoring its potential to reduce the incidence of adverse drug reactions (JAMA, 2001). Her pioneering research on the application of health services research to personalized medicine has revealed insights on how to bridge the gap between emerging technologies and their use in the clinic. Kathryn has also conducted seminal work on HIV, as her analysis of HIV home testing informed the FDA’s decision to approve the first home collection HIV test (New England Journal of Medicine, 1995).

Kathryn has published ~150 peer-reviewed articles in major journals, including JAMA, the New England Journal of Medicine, and Health Affairs and has had continuous funding from the US. National Institutes of Health as a principal investigator for 25 years. She currently serves on the editorial boards of the journal Health Affairs (rated as the top policy journal), Value in Health (a leading outcomes research journal), and all of the leading journals on personalized medicine. Kathryn has served on national and international scientific advisory committees and workshops including work Board of Directors for GenomeCanada, National Academy of Medicine, Food and Drug Administration, Centers for Disease Control and Prevention, and the President’s Council of Advisors on Science and Technology. She has also served as an advisor to various international and industry organizations, including more than 35 biotechnology companies and venture capital firms. She was recently awarded a Rockefeller Foundation global and worked with thethe Patient-Centered Outcomes Research Institute (PCORI) - the largest funder of comparative effectiveness research in the world - developing a research agenda on personalized/precision medicine.

Publications: 

Private Payer and Medicare Coverage for Circulating Tumor DNA Testing: A Historical Analysis of Coverage Policies From 2015 to 2019.

Journal of the National Comprehensive Cancer Network : JNCCN

Douglas MP, Gray SW, Phillips KA

Methods for Moving the Evaluation of Precision Medicine Into Practice and Policy.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Phillips KA

Addressing Challenges of Economic Evaluation in Precision Medicine Using Dynamic Simulation Modeling.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Marshall DA, Grazziotin LR, Regier DA, Wordsworth S, Buchanan J, Phillips K, Ijzerman M

Use of Real-World Evidence in US Payer Coverage Decision-Making for Next-Generation Sequencing-Based Tests: Challenges, Opportunities, and Potential Solutions.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Deverka PA, Douglas MP, Phillips KA

Quantifying Downstream Healthcare Utilization in Studies of Genomic Testing.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Mackay ZP, Dukhovny D, Phillips KA, Beggs AH, Green RC, Parad RB, Christensen KD

Insights From a Temporal Assessment of Increases in US Private Payer Coverage of Tumor Sequencing From 2015 to 2019.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Trosman JR, Douglas MP, Liang SY, Weldon CB, Kurian AW, Kelley RK, Phillips KA

Perspectives of US private payers on insurance coverage for pediatric and prenatal exome sequencing: Results of a study from the Program in Prenatal and Pediatric Genomic Sequencing (P3EGS).

Genetics in medicine : official journal of the American College of Medical Genetics

Trosman JR, Weldon CB, Slavotinek A, Norton ME, Douglas MP, Phillips KA

A Practical First Step Using Needs Assessment and a Survey Approach to Implementing a Clinical Pharmacogenomics Consult Service.

Journal of the American College of Clinical Pharmacy : JAACP

Zakinova A, Long-Boyle JR, French D, Croci R, Wilson L, Phillips KA, Kroetz DL, Shin J, Tamraz B

The Global Market for Next-Generation Sequencing Tests Continues Its Torrid Pace.

The Journal of precision medicine

Phillips KA, Douglas MP

Assessing the Value of Next-Generation Sequencing Technologies: An Introduction.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Phillips KA

Cost Analyses of Genomic Sequencing: Lessons Learned from the MedSeq Project.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Christensen KD, Phillips KA, Green RC, Dukhovny D

Methodological Issues in Assessing the Economic Value of Next-Generation Sequencing Tests: Many Challenges and Not Enough Solutions.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Phillips KA, Deverka PA, Marshall DA, Wordsworth S, Regier DA, Christensen KD, Buchanan J

From the Past to the Present: Insurer Coverage Frameworks for Next-Generation Tumor Sequencing.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Trosman JR, Weldon CB, Gradishar WJ, Benson AB, Cristofanilli M, Kurian AW, Ford JM, Balch A, Watkins J, Phillips KA

Private payer coverage policies for exome sequencing (ES) in pediatric patients: trends over time and analysis of evidence cited.

Genetics in medicine : official journal of the American College of Medical Genetics

Douglas MP, Parker SL, Trosman JR, Slavotinek AM, Phillips KA

Genetic Test Availability And Spending: Where Are We Now? Where Are We Going?

Health affairs (Project Hope)

Phillips KA, Deverka PA, Hooker GW, Douglas MP

Precision Medicine: From Science To Value.

Health affairs (Project Hope)

Ginsburg GS, Phillips KA

Insurance coverage for genomic tests.

Science (New York, N.Y.)

Phillips KA, Trosman JR, Deverka PA, Quinn B, Tunis S, Neumann PJ, Chambers JD, Garrison LP, Douglas MP, Weldon CB

Short-term costs of integrating whole-genome sequencing into primary care and cardiology settings: a pilot randomized trial.

Genetics in medicine : official journal of the American College of Medical Genetics

Christensen KD, Vassy JL, Phillips KA, Blout CL, Azzariti DR, Lu CY, Robinson JO, Lee K, Douglas MP, Yeh JM, Machini K, Stout NK, Rehm HL, McGuire AL, Green RC, Dukhovny D

Corrigendum: What are people willing to pay for whole-genome sequencing information, and who decides what they receive?

Genetics in medicine : official journal of the American College of Medical Genetics

Marshall DA, Gonzalez JM, Johnson FR, MacDonald KV, Pugh A, Douglas MP, Phillips KA

EXAMINING EVIDENCE IN U.S. PAYER COVERAGE POLICIES FOR MULTI-GENE PANELS AND SEQUENCING TESTS.

International journal of technology assessment in health care

Chambers JD, Saret CJ, Anderson JE, Deverka PA, Douglas MP, Phillips KA

Payer coverage policies for multigene tests.

Nature biotechnology

Phillips KA, Deverka PA, Trosman JR, Douglas MP, Chambers JD, Weldon CB, Dervan AP

The price of whole-genome sequencing may be decreasing, but who will be sequenced?

Personalized medicine

Marshall DA, MacDonald KV, Robinson JO, Barcellos LF, Gianfrancesco M, Helm M, McGuire A, Green RC, Douglas MP, Goldman MA, Phillips KA

Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.

Genetics in medicine : official journal of the American College of Medical Genetics

Phillips KA, Deverka PA, Sox HC, Khoury MJ, Sandy LG, Ginsburg GS, Tunis SR, Orlando LA, Douglas MP

Payer Coverage for Hereditary Cancer Panels: Barriers, Opportunities, and Implications for the Precision Medicine Initiative.

Journal of the National Comprehensive Cancer Network : JNCCN

Trosman JR, Weldon CB, Douglas MP, Kurian AW, Kelley RK, Deverka PA, Phillips KA

"What Goes Around Comes Around": Lessons Learned from Economic Evaluations of Personalized Medicine Applied to Digital Medicine.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Phillips KA, Douglas MP, Trosman JR, Marshall DA

Assessing the Value and Implications of Personalized/Precision Medicine and the "Lessons Learned" for Emerging Technologies: An Introduction.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Phillips KA

Decision Making on Medical Innovations in a Changing Health Care Environment: Insights from Accountable Care Organizations and Payers on Personalized Medicine and Other Technologies.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Trosman JR, Weldon CB, Douglas MP, Deverka PA, Watkins JB, Phillips KA

Payer decision making for next-generation sequencing-based genetic tests: insights from cell-free DNA prenatal screening.

Genetics in medicine : official journal of the American College of Medical Genetics

Dervan AP, Deverka PA, Trosman JR, Weldon CB, Douglas MP, Phillips KA

What are people willing to pay for whole-genome sequencing information, and who decides what they receive?

Genetics in medicine : official journal of the American College of Medical Genetics

Marshall DA, Gonzalez JM, Johnson FR, MacDonald KV, Pugh A, Douglas MP, Phillips KA

Availability and payer coverage of BRCA1/2 tests and gene panels.

Nature biotechnology

Clain E, Trosman JR, Douglas MP, Weldon CB, Phillips KA

Economic evidence on identifying clinically actionable findings with whole-genome sequencing: a scoping review.

Genetics in medicine : official journal of the American College of Medical Genetics

Douglas MP, Ladabaum U, Pletcher MJ, Marshall DA, Phillips KA

Key emerging themes for assessing the cost-effectiveness of reporting incidental findings.

Genetics in medicine : official journal of the American College of Medical Genetics

Phillips KA, Ladabaum U, Pletcher MJ, Marshall DA, Douglas MP

Challenges of coverage policy development for next-generation tumor sequencing panels: experts and payers weigh in.

Journal of the National Comprehensive Cancer Network : JNCCN

Trosman JR, Weldon CB, Kelley RK, Phillips KA

Potential public sector cost-savings from over-the-counter access to oral contraceptives.

Contraception

Foster DG, Biggs MA, Phillips KA, Grindlay K, Grossman D

Value of Genetic Testing for Hereditary Colorectal Cancer in a Probability-Based US Online Sample.

Medical decision making : an international journal of the Society for Medical Decision Making

Knight SJ, Mohamed AF, Marshall DA, Ladabaum U, Phillips KA, Walsh JM

Consumer familiarity, perspectives and expected value of personalized medicine with a focus on applications in oncology.

Personalized medicine

Garfeld S, Douglas MP, MacDonald KV, Marshall DA, Phillips KA

Is the ``$1000 Genome'' really $1000? Understanding the full benefits and costs of genomic sequencing.

Technology and health care : official journal of the European Society for Engineering and Medicine

Phillips KA, Pletcher MJ, Ladabaum U

Genomic sequencing: assessing the health care system, policy, and big-data implications.

Health affairs (Project Hope)

Phillips KA, Trosman JR, Kelley RK, Pletcher MJ, Douglas MP, Weldon CB

Prostatitis, steatitis, and diarrhea in a dog following presumptive flea-borne transmission of Bartonella henselae.

Journal of clinical microbiology

Balakrishnan N, Pritchard J, Ericson M, Grindem C, Phillips K, Jennings S, Mathews K, Tran H, Birkenheuer AJ, Breitschwerdt EB

The economic value of personalized medicine tests: what we know and what we need to know.

Genetics in medicine : official journal of the American College of Medical Genetics

Phillips KA, Ann Sakowski J, Trosman J, Douglas MP, Liang SY, Neumann P

Economic Perspectives on Personalized Health Care and Prevention.

Forum for health economics & policy

Phillips KA, Sakowski JA, Liang SY, Ponce NA

Influence of patient preferences on the cost-effectiveness of screening for lynch syndrome.

Journal of oncology practice

Wang G, Kuppermann M, Kim B, Phillips KA, Ladabaum U

Eligibility criteria in private and public coverage policies for BRCA genetic testing and genetic counseling.

Genetics in medicine : official journal of the American College of Medical Genetics

Wang G, Beattie MS, Ponce NA, Phillips KA

Economic evaluation of targeted cancer interventions: critical review and recommendations.

Genetics in medicine : official journal of the American College of Medical Genetics

Elkin EB, Marshall DA, Kulin NA, Ferrusi IL, Hassett MJ, Ladabaum U, Phillips KA

Genomic testing and therapies for breast cancer in clinical practice.

Journal of oncology practice

Haas JS, Phillips KA, Liang SY, Hassett MJ, Keohane C, Elkin EB, Armstrong J, Toscano M

Health technology assessment and private payers' coverage of personalized medicine.

Journal of oncology practice

Trosman JR, Van Bebber SL, Phillips KA

Health technology assessment and private payers's coverage of personalized medicine.

The American journal of managed care

Trosman JR, Van Bebber SL, Phillips KA

How does cost matter in health-care discrete-choice experiments?

Health economics

Johnson FR, Mohamed AF, Ozdemir S, Marshall DA, Phillips KA

Personalized medicine and oncology practice guidelines: a case study of contemporary biomarkers in colorectal cancer.

Journal of the National Comprehensive Cancer Network : JNCCN

Kelley RK, Van Bebber SL, Phillips KA, Venook AP

Capacity building for assessing new technologies: approaches to examining personalized medicine in practice.

Personalized medicine

Van Bebber SL, Trosman JR, Liang SY, Wang G, Marshall DA, Knight S, Phillips KA

Clinical practice patterns and cost effectiveness of human epidermal growth receptor 2 testing strategies in breast cancer patients.

Cancer

Phillips KA, Marshall DA, Haas JS, Elkin EB, Liang SY, Hassett MJ, Ferrusi I, Brock JE, Van Bebber SL

Association of regional variation in primary care physicians' colorectal cancer screening recommendations with individual use of colorectal cancer screening.

Preventing chronic disease

Haas JS, Fitzmaurice G, Brawarsky P, Liang SY, Hiatt RA, Klabunde CN, Brown ML, Phillips KA

Drug withdrawals in the United States: a systematic review of the evidence and analysis of trends.

Current drug safety

Issa AM, Phillips KA, Van Bebber S, Nidamarthy HG, Lasser KE, Haas JS, Alldredge BK, Wachter RM, Bates DW

Measuring patient preferences for colorectal cancer screening using a choice-format survey.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Marshall DA, Johnson FR, Phillips KA, Marshall JK, Thabane L, Kulin NA

Valuing personalized medicine: willingness to pay for genetic testing for colorectal cancer risk.

Personalized medicine

Van Bebber SL, Liang SY, Phillips KA, Marshall D, Walsh J, Kulin N

Trends in colonoscopy for colorectal cancer screening.

Medical care

Phillips KA, Liang SY, Ladabaum U, Haas J, Kerlikowske K, Lieberman D, Hiatt R, Nagamine M, Van Bebber SL

Provider practice models for and costs of delivering medication abortion -- evidence from 11 US abortion care settings.

Contraception

Afable-Munsuz A, Gould H, Stewart F, Phillips KA, Van Bebber SL, Moore C

Innovation in personalized medicine: BiDil® as a case study for integrating clinical and policy developments.

Personalized medicine

Issa AM, Todd Weiss L, Tufail W, Phillips KA, Van Bebber SL

Novel personalized medicine technology: UGT1A1 testing for irinotecan as a case study.

Personalized medicine

Van Bebber SL, Keegan HL, Phillips KA, Issa AM

Rates and predictors of colorectal cancer screening.

Preventing chronic disease

Liang SY, Phillips KA, Nagamine M, Ladabaum U, Haas JS

Biotechnology and Medicare's new technology policy: lessons from three case studies.

Health affairs (Project Hope)

Keenan PS, Neumann PJ, Phillips KA

A review of studies examining stated preferences for cancer screening.

Preventing chronic disease

Phillips KA, Van Bebber S, Marshall D, Walsh J, Thabane L

Diagnostics and biomarker development: priming the pipeline.

Nature reviews. Drug discovery

Phillips KA, Van Bebber S, Issa AM

How the new medicare drug benefit could affect vulnerable populations.

Health affairs (Project Hope)

Gellad WF, Huskamp HA, Phillips KA, Haas JS

Patient costs for medication abortion: results from a study of five clinical practices.

Women's health issues : official publication of the Jacobs Institute of Women's Health

Van Bebber SL, Phillips KA, Weitz TA, Gould H, Stewart F

Prescription drug dispensing limits and patterns.

Managed care interface

Phillips KA, Liang SY, Haas JS, Stebbins M, Alldredge BK

Measuring the value of pharmacogenomics.

Nature reviews. Drug discovery

Phillips KA, Van Bebber SL

The effect of area HMO market share on cancer screening.

Health services research

Baker LC, Phillips KA, Haas JS, Liang SY, Sonneborn D

Variation in screening mammography and Papanicolaou smear by primary care physician specialty and gatekeeper plan (United States).

Cancer causes & control : CCC

Haggstrom DA, Phillips KA, Liang SY, Haas JS, Tye S, Kerlikowske K

Genetic testing and pharmacogenomics: issues for determining the impact to healthcare delivery and costs.

The American journal of managed care

Phillips KA, Veenstra DL, Ramsey SD, Van Bebber SL, Sakowski J

Variation in access to health care for different racial/ethnic groups by the racial/ethnic composition of an individual's county of residence.

Medical care

Haas JS, Phillips KA, Sonneborn D, McCulloch CE, Baker LC, Kaplan CP, Pérez-Stable EJ, Liang SY

Are gatekeeper requirements associated with cancer screening utilization?

Health services research

Phillips KA, Haas JS, Liang SY, Baker LC, Tye S, Kerlikowske K, Sakowski J, Spetz J

Does patient cost sharing matter? Its impact on recommended versus controversial cancer screening services.

The American journal of managed care

Liang SY, Phillips KA, Tye S, Haas JS, Sakowski J

Out-of-pocket expenditures for oral contraceptives and number of packs per purchase.

Journal of the American Medical Women's Association (1972)

Phillips KA, Stotland NE, Liang SY, Spetz J, Haas JS, Oren E

The association of race, socioeconomic status, and health insurance status with the prevalence of overweight among children and adolescents.

American journal of public health

Haas JS, Lee LB, Kaplan CP, Sonneborn D, Phillips KA, Liang SY

Important step forward in HIV-testing technologies [correction of technolgies].

American journal of preventive medicine

Phillips KA

An introduction to cost-effectiveness and cost-benefit analysis of pharmacogenomics.

Pharmacogenomics

Phillips KA, Veenstra D, Van Bebber S, Sakowski J

Is the prevalence of gatekeeping in a community associated with individual trust in medical care?

Medical care

Haas JS, Phillips KA, Baker LC, Sonneborn D, McCulloch CE

Viagra and contraceptives.

Health affairs (Project Hope)

Phillips KA, Spetz J, Haas JS

Measuring what people value: a comparison of "attitude" and "preference" surveys.

Health services research

Phillips KA, Johnson FR, Maddala T

Evaluating the potential impact of pharmacogenomics on ADRs.

Journal of managed care pharmacy : JMCP

Oren E, McCart G, Phillips KA

Impact of the U.S. panel on cost-effectiveness in health and medicine.

American journal of preventive medicine

Phillips KA, Chen JL