Kathryn Phillips, PhD

Professor
Clinical Pharmacy
+1 415 502-8271

Kathryn A. Phillips, PhD, a health services researcher and health economist and leader in the application of new technologies to improve healthcare, is the founding director of the Center for Translational and Policy Research on Personalized Medicine (TRANSPERS) in the School of Pharmacy at the University of California, San Francisco (UCSF). She is also a professor of health economics and health services research in the Department of Clinical Pharmacy at UCSF, with additional appointments in the UCSF Philip R. Lee Institute for Health Policy Studies and UCSF Helen Diller Family Comprehensive Cancer Center

Kathryn focuses on the value of new technologies and how to most effectively and efficiently implement them into health care. Her core specialty is personalized (or precision) medicine — a new era of healthcare where medical interventions can be tailored to individual patients based on their unique genetic make-up. Her work spans multiple disciplines, including basic, clinical and social sciences, and brings together leading experts in academia, industry, healthcare, payers, and government. Kathryn led one of the earliest studies on the societal implications of pharmacogenomics, underscoring its potential to reduce the incidence of adverse drug reactions (JAMA, 2001). Her pioneering research on the application of health services research to personalized medicine has revealed insights on how to bridge the gap between emerging technologies and their use in the clinic. Kathryn has also conducted seminal work on HIV, as her analysis of HIV home testing informed the FDA’s decision to approve the first home collection HIV test (New England Journal of Medicine, 1995).

Kathryn has published ~150 peer-reviewed articles in major journals, including JAMA, the New England Journal of Medicine, and Health Affairs and has had continuous funding from the US. National Institutes of Health as a principal investigator for 25 years. She currently serves on the editorial boards of the journal Health Affairs (rated as the top policy journal), Value in Health (a leading outcomes research journal), and all of the leading journals on personalized medicine. Kathryn has served on national and international scientific advisory committees and workshops including work Board of Directors for GenomeCanada, National Academy of Medicine, Food and Drug Administration, Centers for Disease Control and Prevention, and the President’s Council of Advisors on Science and Technology. She has also served as an advisor to various international and industry organizations, including more than 35 biotechnology companies and venture capital firms. She was recently awarded a Rockefeller Foundation global and worked with thethe Patient-Centered Outcomes Research Institute (PCORI) - the largest funder of comparative effectiveness research in the world - developing a research agenda on personalized/precision medicine.

Publications: 

Payer coverage policies for multigene tests.

Nature biotechnology

Phillips KA, Deverka PA, Trosman JR, Douglas MP, Chambers JD, Weldon CB, Dervan AP

Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.

Genetics in medicine : official journal of the American College of Medical Genetics

Phillips KA, Deverka PA, Sox HC, Khoury MJ, Sandy LG, Ginsburg GS, Tunis SR, Orlando LA, Douglas MP

Payer Coverage for Hereditary Cancer Panels: Barriers, Opportunities, and Implications for the Precision Medicine Initiative.

Journal of the National Comprehensive Cancer Network : JNCCN

Trosman JR, Weldon CB, Douglas MP, Kurian AW, Kelley RK, Deverka PA, Phillips KA

Assessing the Value and Implications of Personalized/Precision Medicine and the "Lessons Learned" for Emerging Technologies: An Introduction.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Phillips KA

Decision Making on Medical Innovations in a Changing Health Care Environment: Insights from Accountable Care Organizations and Payers on Personalized Medicine and Other Technologies.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Trosman JR, Weldon CB, Douglas MP, Deverka PA, Watkins JB, Phillips KA

"What Goes Around Comes Around": Lessons Learned from Economic Evaluations of Personalized Medicine Applied to Digital Medicine.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Phillips KA, Douglas MP, Trosman JR, Marshall DA

Payer decision making for next-generation sequencing-based genetic tests: insights from cell-free DNA prenatal screening.

Genetics in medicine : official journal of the American College of Medical Genetics

Dervan AP, Deverka PA, Trosman JR, Weldon CB, Douglas MP, Phillips KA

What are people willing to pay for whole-genome sequencing information, and who decides what they receive?

Genetics in medicine : official journal of the American College of Medical Genetics

Marshall DA, Gonzalez JM, Johnson FR, MacDonald KV, Pugh A, Douglas MP, Phillips KA

Availability and payer coverage of BRCA1/2 tests and gene panels.

Nature biotechnology

Clain E, Trosman JR, Douglas MP, Weldon CB, Phillips KA

Economic evidence on identifying clinically actionable findings with whole-genome sequencing: a scoping review.

Genetics in medicine : official journal of the American College of Medical Genetics

Douglas MP, Ladabaum U, Pletcher MJ, Marshall DA, Phillips KA

Key emerging themes for assessing the cost-effectiveness of reporting incidental findings.

Genetics in medicine : official journal of the American College of Medical Genetics

Phillips KA, Ladabaum U, Pletcher MJ, Marshall DA, Douglas MP

Challenges of coverage policy development for next-generation tumor sequencing panels: experts and payers weigh in.

Journal of the National Comprehensive Cancer Network : JNCCN

Trosman JR, Weldon CB, Kelley RK, Phillips KA

Potential public sector cost-savings from over-the-counter access to oral contraceptives.

Contraception

Foster DG, Biggs MA, Phillips KA, Grindlay K, Grossman D

Value of Genetic Testing for Hereditary Colorectal Cancer in a Probability-Based US Online Sample.

Medical decision making : an international journal of the Society for Medical Decision Making

Knight SJ, Mohamed AF, Marshall DA, Ladabaum U, Phillips KA, Walsh JM

Consumer familiarity, perspectives and expected value of personalized medicine with a focus on applications in oncology.

Personalized medicine

Garfeld S, Douglas MP, MacDonald KV, Marshall DA, Phillips KA

Is the ``$1000 Genome'' really $1000? Understanding the full benefits and costs of genomic sequencing.

Technology and health care : official journal of the European Society for Engineering and Medicine

Phillips KA, Pletcher MJ, Ladabaum U

Genomic sequencing: assessing the health care system, policy, and big-data implications.

Health affairs (Project Hope)

Phillips KA, Trosman JR, Kelley RK, Pletcher MJ, Douglas MP, Weldon CB

Prostatitis, steatitis, and diarrhea in a dog following presumptive flea-borne transmission of Bartonella henselae.

Journal of clinical microbiology

Balakrishnan N, Pritchard J, Ericson M, Grindem C, Phillips K, Jennings S, Mathews K, Tran H, Birkenheuer AJ, Breitschwerdt EB

Using the coronary artery calcium score to guide statin therapy: a cost-effectiveness analysis.

Circulation. Cardiovascular quality and outcomes

Pletcher MJ, Pignone M, Earnshaw S, McDade C, Phillips KA, Auer R, Zablotska L, Greenland P

The economic value of personalized medicine tests: what we know and what we need to know.

Genetics in medicine : official journal of the American College of Medical Genetics

Phillips KA, Ann Sakowski J, Trosman J, Douglas MP, Liang SY, Neumann P

Influence of patient preferences on the cost-effectiveness of screening for lynch syndrome.

Journal of oncology practice / American Society of Clinical Oncology

Wang G, Kuppermann M, Kim B, Phillips KA, Ladabaum U

Influence of patient preferences on the cost-effectiveness of screening for Lynch syndrome.

The American journal of managed care

Wang G, Kuppermann M, Kim B, Phillips KA, Ladabaum U

Eligibility criteria in private and public coverage policies for BRCA genetic testing and genetic counseling.

Genetics in medicine : official journal of the American College of Medical Genetics

Wang G, Beattie MS, Ponce NA, Phillips KA

Economic evaluation of targeted cancer interventions: critical review and recommendations.

Genetics in medicine : official journal of the American College of Medical Genetics

Elkin EB, Marshall DA, Kulin NA, Ferrusi IL, Hassett MJ, Ladabaum U, Phillips KA

Adequacy of risk-reducing gynaecologic surgery in BRCA1 or BRCA2 mutation carriers and other women at high risk of pelvic serous cancer.

Familial cancer

Kiely BE, Friedlander ML, Milne RL, Stanhope L, Russell P, Jenkins MA, Weideman P, McLachlan SA, Grant P

Prospective study of breast cancer risk for mutation negative women from BRCA1 or BRCA2 mutation positive families.

Breast cancer research and treatment

Harvey SL, Milne RL, McLachlan SA, Friedlander ML, Birch KE, Weideman P

Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis.

Annals of internal medicine

Ladabaum U, Wang G, Terdiman J, Blanco A, Kuppermann M, Boland CR, Ford J, Elkin E, Phillips KA

Gene expression profile testing for breast cancer and the use of chemotherapy, serious adverse effects, and costs of care.

Breast cancer research and treatment

Haas JS, Liang SY, Hassett MJ, Shiboski S, Elkin EB, Phillips KA

Health technology assessment and private payers' coverage of personalized medicine.

Journal of oncology practice / American Society of Clinical Oncology

Trosman JR, Van Bebber SL, Phillips KA

Genomic testing and therapies for breast cancer in clinical practice.

Journal of oncology practice / American Society of Clinical Oncology

Haas JS, Phillips KA, Liang SY, Hassett MJ, Keohane C, Elkin EB, Armstrong J, Toscano M

Genomic testing and therapies for breast cancer in clinical practice.

The American journal of managed care

Haas JS, Phillips KA, Liang SY, Hassett MJ, Keohane C, Elkin EB, Armstrong J, Toscano M

Health technology assessment and private payers's coverage of personalized medicine.

The American journal of managed care

Trosman JR, Van Bebber SL, Phillips KA

How does cost matter in health-care discrete-choice experiments?

Health economics

Johnson FR, Mohamed AF, Ozdemir S, Marshall DA, Phillips KA

Personalized medicine and oncology practice guidelines: a case study of contemporary biomarkers in colorectal cancer.

Journal of the National Comprehensive Cancer Network : JNCCN

Kelley RK, Van Bebber SL, Phillips KA, Venook AP

Coverage policy development for personalized medicine: private payer perspectives on developing policy for the 21-gene assay.

Journal of oncology practice / American Society of Clinical Oncology

Trosman JR, Van Bebber SL, Phillips KA

Capacity building for assessing new technologies: approaches to examining personalized medicine in practice.

Personalized medicine

Van Bebber SL, Trosman JR, Liang SY, Wang G, Marshall DA, Knight S, Phillips KA

Medicare formulary coverage for top-selling biologics.

Nature biotechnology

Liang SY, Haas JS, Phillips KA

Clinical practice patterns and cost effectiveness of human epidermal growth receptor 2 testing strategies in breast cancer patients.

Cancer

Phillips KA, Marshall DA, Haas JS, Elkin EB, Liang SY, Hassett MJ, Ferrusi I, Brock JE, Van Bebber SL

Effects of simplifying choice tasks on estimates of taste heterogeneity in stated-choice surveys.

Social science & medicine (1982)

Johnson FR, Ozdemir S, Phillips KA

Addressing the challenges of the clinical application of pharmacogenetic testing.

Clinical pharmacology and therapeutics

Ikediobi ON, Shin J, Nussbaum RL, Phillips KA

A health services research agenda for cellular, molecular and genomic technologies in cancer care.

Public health genomics

Wideroff L, Phillips KA, Randhawa G, Ambs A, Armstrong K, Bennett CL, Brown ML, Donaldson MS, Follen M, Goldie SJ, Hiatt RA, Khoury MJ, Lewis G, McLeod HL, Piper M, Powell I, Schrag D, Schulman KA, Scott J

Insured women and payment for elective abortion.

Women's health issues : official publication of the Jacobs Institute of Women's Health

Lee JA, Afable-Munsuz A, Van Bebber SL, Phillips KA

Association of regional variation in primary care physicians' colorectal cancer screening recommendations with individual use of colorectal cancer screening.

Preventing chronic disease

Haas JS, Fitzmaurice G, Brawarsky P, Liang SY, Hiatt RA, Klabunde CN, Brown ML, Phillips KA

Drug withdrawals in the United States: a systematic review of the evidence and analysis of trends.

Current drug safety

Issa AM, Phillips KA, Van Bebber S, Nidamarthy HG, Lasser KE, Haas JS, Alldredge BK, Wachter RM, Bates DW

Measuring patient preferences for colorectal cancer screening using a choice-format survey.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Marshall DA, Johnson FR, Phillips KA, Marshall JK, Thabane L, Kulin NA

Angiotensin receptor blockers on the formularies of Medicare drug plans.

Journal of general internal medicine

Gellad WF, Huskamp HA, Phillips KA, Haas JS

Trends in colonoscopy for colorectal cancer screening.

Medical care

Phillips KA, Liang SY, Ladabaum U, Haas J, Kerlikowske K, Lieberman D, Hiatt R, Nagamine M, Van Bebber SL

Measuring managed care and its environment using national surveys: a review and assessment.

Medical care research and review : MCRR

Liang SY, Phillips KA, Haas JS

Provider practice models for and costs of delivering medication abortion -- evidence from 11 US abortion care settings.

Contraception

Afable-Munsuz A, Gould H, Stewart F, Phillips KA, Van Bebber SL, Moore C

Rates and predictors of colorectal cancer screening.

Preventing chronic disease

Liang SY, Phillips KA, Nagamine M, Ladabaum U, Haas JS

A conceptual framework for developing teaching cases: a review and synthesis of the literature across disciplines.

Medical education

Kim S, Phillips WR, Pinsky L, Brock D, Phillips K, Keary J

Biotechnology and Medicare's new technology policy: lessons from three case studies.

Health affairs (Project Hope)

Keenan PS, Neumann PJ, Phillips KA

A randomized controlled trial of a decision aid for women at increased risk of ovarian cancer.

Medical decision making : an international journal of the Society for Medical Decision Making

Tiller K, Meiser B, Gaff C, Kirk J, Dudding T, Phillips KA, Friedlander M, Tucker K

A review of studies examining stated preferences for cancer screening.

Preventing chronic disease

Phillips KA, Van Bebber S, Marshall D, Walsh J, Thabane L

Diagnostics and biomarker development: priming the pipeline.

Nature reviews. Drug discovery

Phillips KA, Van Bebber S, Issa AM

Colorectal cancer screening differential costs for younger versus older Americans.

American journal of preventive medicine

Ladabaum U, Phillips KA

How the new medicare drug benefit could affect vulnerable populations.

Health affairs (Project Hope)

Gellad WF, Huskamp HA, Phillips KA, Haas JS

Patient costs for medication abortion: results from a study of five clinical practices.

Women's health issues : official publication of the Jacobs Institute of Women's Health

Van Bebber SL, Phillips KA, Weitz TA, Gould H, Stewart F

Cost-effectiveness analysis of genetic testing for familial long QT syndrome in symptomatic index cases.

Heart rhythm : the official journal of the Heart Rhythm Society

Phillips KA, Ackerman MJ, Sakowski J, Berul CI

Prescription drug dispensing limits and patterns.

Managed care interface

Phillips KA, Liang SY, Haas JS, Stebbins M, Alldredge BK

Potential savings from substituting generic drugs for brand-name drugs: medical expenditure panel survey, 1997-2000.

Annals of internal medicine

Haas JS, Phillips KA, Gerstenberger EP, Seger AC

Measuring the value of pharmacogenomics.

Nature reviews. Drug discovery

Phillips KA, Van Bebber SL

A qualitative study of insurers' coverage for mifepristone-induced abortion.

Managed care interface

Gemperli MP, Stewart FH, Phillips KA, Sakowski J, Van Bebber S, Bergthold L

The effect of area HMO market share on cancer screening.

Health services research

Baker LC, Phillips KA, Haas JS, Liang SY, Sonneborn D

Variation in screening mammography and Papanicolaou smear by primary care physician specialty and gatekeeper plan (United States).

Cancer causes & control : CCC

Haggstrom DA, Phillips KA, Liang SY, Haas JS, Tye S, Kerlikowske K

Variation in access to health care for different racial/ethnic groups by the racial/ethnic composition of an individual's county of residence.

Medical care

Haas JS, Phillips KA, Sonneborn D, McCulloch CE, Baker LC, Kaplan CP, Pérez-Stable EJ, Liang SY

Genetic testing and pharmacogenomics: issues for determining the impact to healthcare delivery and costs.

The American journal of managed care

Phillips KA, Veenstra DL, Ramsey SD, Van Bebber SL, Sakowski J

Willingness to recommend a health plan: who is dissatisfied and what don't they like?

The American journal of managed care

Sakowski JA, Phillips KA, Liang SY, Haas JS

Are gatekeeper requirements associated with cancer screening utilization?

Health services research

Phillips KA, Haas JS, Liang SY, Baker LC, Tye S, Kerlikowske K, Sakowski J, Spetz J

Does patient cost sharing matter? Its impact on recommended versus controversial cancer screening services.

The American journal of managed care

Liang SY, Phillips KA, Tye S, Haas JS, Sakowski J

Out-of-pocket expenditures for oral contraceptives and number of packs per purchase.

Journal of the American Medical Women's Association (1972)

Phillips KA, Stotland NE, Liang SY, Spetz J, Haas JS, Oren E

The association of race, socioeconomic status, and health insurance status with the prevalence of overweight among children and adolescents.

American journal of public health

Haas JS, Lee LB, Kaplan CP, Sonneborn D, Phillips KA, Liang SY

An experiment on simplifying conjoint analysis designs for measuring preferences.

Health economics

Maddala T, Phillips KA, Reed Johnson F

Important step forward in HIV-testing technologies [correction of technolgies].

American journal of preventive medicine

Phillips KA

Is the prevalence of gatekeeping in a community associated with individual trust in medical care?

Medical care

Haas JS, Phillips KA, Baker LC, Sonneborn D, McCulloch CE

An introduction to cost-effectiveness and cost-benefit analysis of pharmacogenomics.

Pharmacogenomics

Phillips KA, Veenstra D, Van Bebber S, Sakowski J

Viagra and contraceptives.

Health affairs (Project Hope)

Phillips KA, Spetz J, Haas JS

Measuring what people value: a comparison of "attitude" and "preference" surveys.

Health services research

Phillips KA, Johnson FR, Maddala T

Evaluating the potential impact of pharmacogenomics on ADRs.

Journal of managed care pharmacy : JMCP

Oren E, McCart G, Phillips KA

Impact of the U.S. panel on cost-effectiveness in health and medicine.

American journal of preventive medicine

Phillips KA, Chen JL

The effect of risk factor reductions between 1981 and 1990 on coronary heart disease incidence, prevalence, mortality and cost.

Journal of the American College of Cardiology

Goldman L, Phillips KA, Coxson P, Goldman PA, Williams L, Hunink MG, Weinstein MC

Deciding where and how to be tested for HIV: what matters most?

Journal of acquired immune deficiency syndromes (1999)

Skolnik HS, Phillips KA, Binson D, Dilley JW

Health and economic benefits of increased beta-blocker use following myocardial infarction.

JAMA

Phillips KA, Shlipak MG, Coxson P, Heidenreich PA, Hunink MG, Goldman PA, Williams LW, Weinstein MC, Goldman L

Personality disorders, history of trauma, and posttraumatic stress disorder in subjects with anxiety disorders.

Comprehensive psychiatry

Shea MT, Zlotnick C, Dolan R, Warshaw MG, Phillips KA, Brown P, Keller MB

Barriers to care among racial/ethnic groups under managed care.

Health affairs (Project Hope)

Phillips KA, Mayer ML, Aday LA

Home sample collection for HIV testing.

JAMA

Phillips KA, Morin S, Coates T, Fernyak S, Marsh A, Ramos-Irizarry L

Assessing the cost-effectiveness of pharmacogenomics.

AAPS pharmSci

Veenstra DL, Higashi MK, Phillips KA

Use of preventive services by managed care enrollees: an updated perspective.

Health affairs (Project Hope)

Phillips KA, Fernyak S, Potosky AL, Schauffler HH, Egorin M

Factors associated with women's adherence to mammography screening guidelines.

Health services research

Phillips KA, Kerlikowske K, Baker LC, Chang SW, Brown ML

The costs and outcomes of restricting public access to poison control centers. Results from a natural experiment.

Medical care

Phillips KA, Homan RK, Hiatt PH, Luft HS, Kearney TE, Heard SE, Olson KR

The policy implications of using hospital and physician volumes as "indicators" of quality of care in a changing health care environment.

International journal for quality in health care : journal of the International Society for Quality in Health Care / ISQua

Phillips KA, Luft HS

Willingness to pay for poison control centers.

Journal of health economics

Phillips KA, Homan RK, Luft HS, Hiatt PH, Olson KR, Kearney TE, Heard SE

Predictors of follow-through on plans to be tested for HIV.

American journal of preventive medicine

Phillips KA, Coates TJ, Catania JA

HIV counseling and testing of pregnant women.

JAMA

Phillips KA, Bleecker T, Morrison KR, Sonnad SS

Decisions to get HIV tested and to accept antiretroviral therapies among gay/bisexual men: implications for secondary prevention efforts.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association

Stall R, Hoff C, Coates TJ, Paul J, Phillips KA, Ekstrand M, Kegeles S, Catania J, Daigle D, Diaz R

Improving the use of information in medical effectiveness research.

International journal for quality in health care : journal of the International Society for Quality in Health Care / ISQua

Phillips KA, Bero LA

Consistency in self-reports of HIV testing: longitudinal findings from the National AIDS Behavioral Surveys.

Public health reports (Washington, D.C. : 1974)

Phillips KA, Catania JA

Predictors of repeat HIV testing among gay and bisexual men.

AIDS (London, England)

Phillips KA, Paul J, Kegeles S, Stall R, Hoff C, Coates TJ

Potential use of home HIV testing.

The New England journal of medicine

Phillips KA, Flatt SJ, Morrison KR, Coates TJ

Who plans to be tested for HIV or would get tested if no one could find out the results?

American journal of preventive medicine

Phillips KA, Coates TJ, Eversley RB, Catania JA

Role of HIV counseling and testing in changing risk behavior in developing countries.

AIDS (London, England)

De Zoysa I, Phillips KA, Kamenga MC, O'Reilly KR, Sweat MD, White RA, Grinstead OA, Coates TJ

The cost-effectiveness of voluntary counseling and testing of hospital inpatients for HIV infection.

JAMA

Lurie P, Avins AL, Phillips KA, Kahn JG, Lowe RA, Ciccarone D

The cost-effectiveness of HIV testing of physicians and dentists in the United States.

JAMA

Phillips KA, Lowe RA, Kahn JG, Lurie P, Avins AL, Ciccarone D

Coronary angioplasty. Statewide experience in California.

Circulation

Ritchie JL, Phillips KA, Luft HS

Subjective knowledge of AIDS and use of HIV testing.

American journal of public health

Phillips KA

Factors associated with voluntary HIV testing for African-Americans and Hispanics.

AIDS education and prevention : official publication of the International Society for AIDS Education

Phillips KA

Who seeks HIV testing? The impact of risk, knowledge, and state regulatory policy on the testing decision.

Inquiry : a journal of medical care organization, provision and financing

Paringer L, Phillips KA, Hu TW