Laura Esserman, MD

Professor
Surgery
+1 415 885-7691

Dr. Laura Esserman, M.D., M.B.A is a surgeon and breast cancer oncology specialist practicing at the UCSF Carol Franc Buck Breast Care Center where she has also held the position of Director since 1996. She co-leads the Breast Oncology Program, the largest of the UCSF Helen Diller Comprehensive Cancer Center's multidisciplinary programs. The program is comprised of 69 faculty members who represent 16 academic specialties and is internationally recognized and well-established with major initiatives in epidemiology, genetics, biology, therapeutics, and clinical cancer care. She is a professor of Surgery & Radiology at UCSF and faculty at the UCSF Helen Diller Family Comprehensive Cancer Center where she founded the program in Translational Informatics. As part of this program, her research has focused on bioinformatics, medical and clinical informatics, systems integration, and clinical care delivery.

She has worked at UCSF to develop interdisciplinary teams of clinicians and researchers to bring the best care to patients and find the best platform to integrate translational research and improve the delivery of breast cancer care. In 2005, she received the NCI SPORE Investigator of the Year Award, an internationally recognized honor and designation.

She is the Principle Investigator of the I-SPY TRIAL program, a multi-site neoadjuvant clinical trial that has evolved into a model for translational research and innovation in clinical trial design.

Dr. Esserman has recently launched a University of California-wide breast cancer initiative called the Athena Breast Health Network, a project designed to follow 400,000 women from screening through treatment and outcomes, incorporating the latest in molecular testing and web-based tools into the course of care.

Dr. Esserman is nationally and internationally known as a leader in the field of breast cancer and has published over 150 articles in peer-reviewed journals covering all aspects of breast health including information systems, immunology, decision making, health policy and the use of imaging. She speaks extensively at public and private forums within the U.S. and internationally. Overall, Dr. Esserman's research and writing tends to focus on the goal of giving patients better access to accurate information so that they can become partners in their health care.

She is a member of President Obama’s Council of Advisors on Science and Technology (PCAST) Working Group on Advancing Innovation in Drug Development and Evaluation, which is studying how the federal government can best support science-based innovation in the process of drug development and regulatory evaluation. In addition, she is a contributing member of a “taskforce” for President Obama’s Council of Advisors on Science and Technology.

Dr. Esserman received her Bachelor's degree in History of Science from Harvard University and completed her M.D. at Stanford University. She completed her surgery residency and oncology fellowship at Stanford University Medical Center. After her training, she joined the faculty at Stanford and received a Hartford fellowship to attend Stanford Business School where she received her M.B.A. in 1993. She then joined the faculty at the University of California, San Francisco.

Publications: 

Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy.

Breast cancer research and treatment

Rice BA, Ver Hoeve ES, DeLuca AN, Esserman LJ, Rugo HS, Melisko ME

Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.

Breast cancer research : BCR

Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, Pawlowska N, Thomas S, Dhawan M, Aggarwal R, Munster PN, Esserman LJ, Ruan W, Wu AHB, Yee D, Dartois V, Savic RM, Wolf DM, van 't Veer L

Tamoxifen therapy benefit for patients with 70-gene signature high and low risk.

Breast cancer research and treatment

van 't Veer LJ, Yau C, Yu NY, Benz CC, Nordenskjöld B, Fornander T, Stål O, Esserman LJ, Lindström LS

Erratum to: Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.

Breast cancer research and treatment

Chien AJ, Chambers J, Mcauley F, Kaplan T, Letourneau J, Hwang J, Kim MO, Melisko ME, Rugo HS, Esserman LJ, Rosen MP

Indications for Postmastectomy Radiation After Neoadjuvant Chemotherapy in ypN0 and ypN1-3 Axillary Node-Positive Women.

Clinical breast cancer

Fowble B, Jairam AK, Wang F, Peled A, Alvarado M, Ewing C, Esserman L, Park C, Lazar A

Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.

JAMA oncology

Esserman LJ, Yau C, Thompson CK, van 't Veer LJ, Borowsky AD, Hoadley KA, Tobin NP, Nordenskjöld B, Fornander T, Stål O, Benz CC, Lindström LS

Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).

Breast cancer research and treatment

Campbell JI, Yau C, Krass P, Moore D, Carey LA, Au A, Chhieng D, Giri D, Livasy C, Mies C, Rabban J, Sarode VR, Singh B, Esserman L, Chen YY

Complications After Total Skin-Sparing Mastectomy and Expander-Implant Reconstruction: Effects of Radiation Therapy on the Stages of Reconstruction.

Annals of plastic surgery

Peled AW, Sears M, Wang F, Foster RD, Alvarado M, Wong J, Ewing CA, Sbitany H, Esserman LJ, Fowble B

Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.

Breast cancer research and treatment

Jo Chien A, Chambers J, Mcauley F, Kaplan T, Letourneau J, Hwang J, Kim MO, Melisko ME, Rugo HS, Esserman LJ, Rosen MP

Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer.

JAMA

Rugo HS, Klein P, Melin SA, Hurvitz SA, Melisko ME, Moore A, Park G, Mitchel J, Bågeman E, D'Agostino RB, Ver Hoeve ES, Esserman L, Cigler T

Precision surgery and avoiding over-treatment.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Hosseini A, Khoury AL, Esserman LJ

Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.

Journal of the National Cancer Institute

Shieh Y, Eklund M, Madlensky L, Sawyer SD, Thompson CK, Stover Fiscalini A, Ziv E, Van't Veer LJ, Esserman LJ, Tice JA

Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ellis MJ, Suman VJ, Hoog J, Goncalves R, Sanati S, Creighton CJ, DeSchryver K, Crouch E, Brink A, Watson M, Luo J, Tao Y, Barnes M, Dowsett M, Budd GT, Winer E, Silverman P, Esserman L, Carey L, Ma CX, Unzeitig G, Pluard T, Whitworth P, Babiera G, Guenther JM, Dayao Z, Ota D, Leitch M, Olson JA, Allred DC, Hunt K

Dedicated Breast Positron Emission Tomography for the Evaluation of Early Response to Neoadjuvant Chemotherapy in Breast Cancer.

Clinical breast cancer

Jones EF, Ray KM, Li W, Seo Y, Franc BL, Chien AJ, Esserman LJ, Pampaloni MH, Joe BN, Hylton NM

MR spectroscopy of breast cancer for assessing early treatment response: Results from the ACRIN 6657 MRS trial.

Journal of magnetic resonance imaging : JMRI

Bolan PJ, Kim E, Herman BA, Newstead GM, Rosen MA, Schnall MD, Pisano ED, Weatherall PT, Morris EA, Lehman CD, Garwood M, Nelson MT, Yee D, Polin SM, Esserman LJ, Gatsonis CA, Metzger GJ, Newitt DC, Partridge SC, Hylton NM

Effect of MR Imaging Contrast Thresholds on Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes: A Subgroup Analysis of the ACRIN 6657/I-SPY 1 TRIAL.

Tomography : a journal for imaging research

Li W, Arasu V, Newitt DC, Jones EF, Wilmes L, Gibbs J, Kornak J, Joe BN, Esserman LJ, Hylton NM

Adaptive Randomization of Neratinib in Early Breast Cancer.

The New England journal of medicine

Berry D, Esserman L

PIPELINEs: Creating Comparable Clinical Knowledge Efficiently by Linking Trial Platforms.

Clinical pharmacology and therapeutics

Trusheim MR, Shrier AA, Antonijevic Z, Beckman RA, Campbell RK, Chen C, Flaherty KT, Loewy J, Lacombe D, Madhavan S, Selker HP, Esserman LJ

The I-SPY approach to drug development.

Clinical advances in hematology & oncology : H&O

Esserman L

The Novel Application of Genomic Profiling Assays to Shorten Inactive Status for Potential Kidney Transplant Recipients With Breast Cancer.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Mukhtar RA, Piper ML, Freise C, Van't Veer LJ, Baehner FL, Esserman LJ

Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.

The New England journal of medicine

Rugo HS, Olopade OI, DeMichele A, Yau C, van 't Veer LJ, Buxton MB, Hogarth M, Hylton NM, Paoloni M, Perlmutter J, Symmans WF, Yee D, Chien AJ, Wallace AM, Kaplan HG, Boughey JC, Haddad TC, Albain KS, Liu MC, Isaacs C, Khan QJ, Lang JE, Viscusi RK, Pusztai L, Moulder SL, Chui SY, Kemmer KA, Elias AD, Edmiston KK, Euhus DM, Haley BB, Nanda R, Northfelt DW, Tripathy D, Wood WC, Ewing C, Schwab R, Lyandres J, Davis SE, Hirst GL, Sanil A, Berry DA, Esserman LJ

Adaptive Randomization of Neratinib in Early Breast Cancer.

The New England journal of medicine

Park JW, Liu MC, Yee D, Yau C, van 't Veer LJ, Symmans WF, Paoloni M, Perlmutter J, Hylton NM, Hogarth M, DeMichele A, Buxton MB, Chien AJ, Wallace AM, Boughey JC, Haddad TC, Chui SY, Kemmer KA, Kaplan HG, Isaacs C, Nanda R, Tripathy D, Albain KS, Edmiston KK, Elias AD, Northfelt DW, Pusztai L, Moulder SL, Lang JE, Viscusi RK, Euhus DM, Haley BB, Khan QJ, Wood WC, Melisko M, Schwab R, Helsten T, Lyandres J, Davis SE, Hirst GL, Sanil A, Esserman LJ, Berry DA

Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers.

Proteomics. Clinical applications

Katchman BA, Barderas R, Alam R, Chowell D, Field MS, Esserman LJ, Wallstrom G, LaBaer J, Cramer DW, Hollingsworth MA, Anderson KS

Outcomes Following Oncoplastic Reduction Mammoplasty: A Systematic Review.

Annals of plastic surgery

Piper ML, Esserman LJ, Sbitany H, Peled AW

Population-based screening for cancer: hope and hype.

Nature reviews. Clinical oncology

Shieh Y, Eklund M, Sawaya GF, Black WC, Kramer BS, Esserman LJ

Effect of Imaging Parameter Thresholds on MRI Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes.

PloS one

Lo WC, Li W, Jones EF, Newitt DC, Kornak J, Wilmes LJ, Esserman LJ, Hylton NM

A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies.

Breast cancer research and treatment

Chien AJ, Cockerill A, Fancourt C, Schmidt E, Moasser MM, Rugo HS, Melisko ME, Ko AH, Kelley RK, Korn WM, Esserman LJ, Van't Veer L, Yau C, Wolf DM, Munster PN

Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)?

Breast (Edinburgh, Scotland)

Winters ZE, Horsnell J, Schmid P, Jones JL, Shaaban A, Maxwell AJ, Williams N, Esserman L, Jatoi I, Brunt AM

Detection of ductal carcinoma in situ and subsequent interval cancers.

BMJ (Clinical research ed.)

Shieh Y, Eklund M, Esserman L

CLINICAL DECISIONS. Ductal Carcinoma In Situ.

The New England journal of medicine

Merrill AL, Esserman L, Morrow M

Less Is More: The Evolving Surgical Approach to Breast Cancer.

American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting

Esserman L, Gallant E, Alvarado M

Tissue Expander Reconstruction After Total Skin-Sparing Mastectomy: Defining the Effects of Coverage Technique on Nipple/Areola Preservation.

Annals of plastic surgery

Sbitany H, Wang F, Peled AW, Alvarado M, Ewing CA, Esserman LJ, Foster RD

The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander-Implant Exchange in Prosthetic Breast Reconstruction.

Plastic and reconstructive surgery

Wang F, Peled AW, Chin R, Fowble B, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H

Neoadjuvant as Future for Drug Development in Breast Cancer-Response.

Clinical cancer research : an official journal of the American Association for Cancer Research

DeMichele A, Yee D, Paoloni M, Berry D, Esserman LJ

Sentinel Lymph Node Mapping in Post-Mastectomy Chest Wall Recurrences: Influence on Radiation Treatment Fields and Outcome.

Annals of surgical oncology

Johnson J, Esserman L, Ewing C, Alvarado M, Park C, Fowble B

Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival-Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL.

Radiology

Hylton NM, Gatsonis CA, Rosen MA, Lehman CD, Newitt DC, Partridge SC, Bernreuter WK, Pisano ED, Morris EA, Weatherall PT, Polin SM, Newstead GM, Marques HS, Esserman LJ, Schnall MD

Negative Genetic Testing Does Not Deter Contralateral Prophylactic Mastectomy in Younger Patients with Greater Family Histories of Breast Cancer.

Annals of surgical oncology

Wang F, Amara D, Peled AW, Sbitany H, Foster RD, Ewing CA, Alvarado M, Esserman LJ

Association of tamoxifen use and ovarian function in patients with invasive or pre-invasive breast cancer.

Breast cancer research and treatment

Chien AJ, Duralde E, Hwang R, Tsung K, Kao CN, Rugo HS, Melisko ME, Esserman LJ, Munster PN, Cedars M, Kerlikowske K, McCulloch CE, Rosen MP

Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Provenzano E, Bossuyt V, Viale G, Cameron D, Badve S, Denkert C, MacGrogan G, Penault-Llorca F, Boughey J, Curigliano G, Dixon JM, Esserman L, Fastner G, Kuehn T, Peintinger F, von Minckwitz G, White J, Yang W, Symmans WF

How to use magnetic resonance imaging following neoadjuvant chemotherapy in locally advanced breast cancer.

World journal of clinical cases

Price ER, Wong J, Mukhtar R, Hylton N, Esserman LJ

In Regard to Hepel and Wazer.

International journal of radiation oncology, biology, physics

Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M

Expanding the Indications for Total Skin-Sparing Mastectomy: Is It Safe for Patients with Locally Advanced Disease?

Annals of surgical oncology

Peled AW, Wang F, Foster RD, Alvarado M, Ewing CA, Sbitany H, Esserman LJ

Preventing Overdiagnosis and Overtreatment: Just the Next Step in the Evolution of Breast Cancer Care.

Journal of the National Comprehensive Cancer Network : JNCCN

Mukhtar RA, Wong JM, Esserman LJ

Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response.

Breast cancer research : BCR

Magbanua MJ, Wolf DM, Yau C, Davis SE, Crothers J, Au A, Haqq CM, Livasy C, Rugo HS

Tumor Involvement of the Nipple in Total Skin-Sparing Mastectomy: Strategies for Management.

Annals of surgical oncology

Amara D, Peled AW, Wang F, Ewing CA, Alvarado M, Esserman LJ

Coaching patients in the use of decision and communication aids: RE-AIM evaluation of a patient support program.

BMC health services research

Belkora J, Volz S, Loth M, Teng A, Zarin-Pass M, Moore D, Esserman L

Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration.

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO

Bossuyt V, Provenzano E, Symmans WF, Boughey JC, Coles C, Curigliano G, Dixon JM, Esserman LJ, Fastner G, Kuehn T, Peintinger F, von Minckwitz G, White J, Yang W, Badve S, Denkert C, MacGrogan G, Penault-Llorca F, Viale G, Cameron D

Comparison of Mammographic Findings Following Oncoplastic Mammoplasty and Lumpectomy Without Reconstruction.

Annals of surgical oncology

Piper M, Peled AW, Sbitany H, Foster RD, Esserman LJ, Price ER

Approaches to microvascular breast reconstruction after total skin-sparing mastectomy: a comparison of techniques.

Annals of plastic surgery

Raghavan S, Peled AW, Hansen SL, Esserman LJ, Sbitany H

Rates of Reconstruction Failure in Patients Undergoing Immediate Reconstruction With Tissue Expanders and/or Implants and Postmastectomy Radiation Therapy.

International journal of radiation oncology, biology, physics

Fowble B, Park C, Wang F, Peled A, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H, Hanlon A

Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer.

International journal of radiation oncology, biology, physics

Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M

The impact of breast mass on outcomes of total skin-sparing mastectomy and immediate tissue expander-based breast reconstruction.

Plastic and reconstructive surgery

Wang F, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H

The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

DeMichele A, Yee D, Berry DA, Albain KS, Benz CC, Boughey J, Buxton M, Chia SK, Chien AJ, Chui SY, Clark A, Edmiston K, Elias AD, Forero-Torres A, Haddad TC, Haley B, Haluska P, Hylton NM, Isaacs C, Kaplan H, Korde L, Leyland-Jones B, Liu MC, Melisko M, Minton SE, Moulder SL, Nanda R, Olopade OI, Paoloni M, Park JW, Parker BA, Perlmutter J, Petricoin EF, Rugo H, Symmans F, Tripathy D, van't Veer LJ, Viscusi RK, Wallace A, Wolf D, Yau C, Esserman LJ

Mammographic Changes After Oncoplastic Reduction Mammoplasty.

Annals of plastic surgery

Piper M, Peled AW, Price ER, Foster RD, Esserman LJ, Sbitany H

Development, implementation, and initial evaluation of a foundational open interoperability standard for oncology treatment planning and summarization.

Journal of the American Medical Informatics Association : JAMIA

Warner JL, Maddux SE, Hughes KS, Krauss JC, Yu PP, Shulman LN, Mayer DK, Hogarth M, Shafarman M, Stover Fiscalini A, Esserman L, Alschuler L, Koromia GA, Gonzaga Z, Ambinder EP

Preoperative Breast Pain Predicts Persistent Breast Pain and Disability After Breast Cancer Surgery.

Journal of pain and symptom management

Langford DJ, Schmidt B, Levine JD, Abrams G, Elboim C, Esserman L, Hamolsky D, Mastick J, Paul SM, Cooper B, Kober K, Dodd M, Dunn L, Aouizerat B, Miaskowski C

Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Marks JR, Anderson KS, Engstrom P, Godwin AK, Esserman LJ, Longton G, Iversen ES, Mathew A, Patriotis C, Pepe MS

SIS.NET: a randomized controlled trial evaluating a web-based system for symptom management after treatment of breast cancer.

Cancer

Wheelock AE, Bock MA, Martin EL, Hwang J, Ernest ML, Rugo HS, Esserman LJ, Melisko ME

Expression profiling of circulating tumor cells in metastatic breast cancer.

Breast cancer research and treatment

Lang JE, Scott JH, Wolf DM, Novak P, Punj V, Magbanua MJ, Zhu W, Mineyev N, Haqq CM, Crothers JR, Esserman LJ, Tripathy D, van 't Veer L, Park JW

Immediate implant-based breast reconstruction following total skin-sparing mastectomy: defining the risk of preoperative and postoperative radiation therapy for surgical outcomes.

Plastic and reconstructive surgery

Sbitany H, Wang F, Peled AW, Lentz R, Alvarado M, Ewing CA, Esserman LJ, Fowble B, Foster RD

Aggregate cost of mammography screening in the United States.

Annals of internal medicine

Eklund M, O'Donoghue C, Esserman LJ

Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction.

Annals of surgical oncology

Degnim AC, Hoskin TL, Brahmbhatt RD, Warren-Peled A, Loprinzi M, Pavey ES, Boughey JC, Hieken TJ, Jacobson S, Lemaine V, Jakub JW, Irwin C, Foster RD, Sbitany H, Saint-Cyr M, Duralde E, Ramaker S, Chin R, Sieg M, Wildeman M, Scow JS, Patel R, Ballman K, Baddour LM, Esserman LJ

Impact of total skin-sparing mastectomy incision type on reconstructive complications following radiation therapy.

Plastic and reconstructive surgery

Peled AW, Foster RD, Ligh C, Esserman LJ, Fowble B, Sbitany H

Haste makes waste, but lack of urgency is opportunity lost.

Breast cancer research and treatment

Esserman L, Hayes M, Alvarado M

Moving beyond the breast cancer screening debate.

Journal of women's health (2002)

Esserman L, O'Kane ME

Total skin-sparing mastectomy and immediate breast reconstruction: an evolution of technique and assessment of outcomes.

Annals of surgical oncology

Wang F, Peled AW, Garwood E, Fiscalini AS, Sbitany H, Foster RD, Alvarado M, Ewing C, Hwang ES, Esserman LJ

Imaging features of HER2 overexpression in breast cancer: a systematic review and meta-analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Elias SG, Adams A, Wisner DJ, Esserman LJ, van't Veer LJ, Mali WP, Gilhuijs KG, Hylton NM

Patient-reported outcomes and satisfaction after total skin-sparing mastectomy and immediate expander-implant reconstruction.

Annals of plastic surgery

Peled AW, Duralde E, Foster RD, Fiscalini AS, Esserman LJ, Hwang ES, Sbitany H

Addressing overdiagnosis and overtreatment in cancer: a prescription for change.

The Lancet. Oncology

Esserman LJ, Thompson IM, Reid B, Nelson P, Ransohoff DF, Welch HG, Hwang S, Berry DA, Kinzler KW, Black WC, Bissell M, Parnes H, Srivastava S

Local recurrence rates are low in high-risk neoadjuvant breast cancer in the I-SPY 1 Trial (CALGB 150007/150012; ACRIN 6657).

Annals of surgical oncology

Cureton EL, Yau C, Alvarado MD, Krontiras H, Ollila DW, Ewing CA, Monnier S, Esserman LJ

Fifty years of age-based screening: time for a new risk-based screening approach.

Evidence-based medicine

Kerlikowske K, O'Kane ME, Esserman LJ

Accelerated approval for pertuzumab in the neoadjuvant setting: winds of change?

Clinical cancer research : an official journal of the American Association for Cancer Research

Esserman LJ, DeMichele A

Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time?

Breast cancer research and treatment

Esserman LJ, Alvarado MD, Howe RJ, Mohan AJ, Harrison B, Park C, O'Donoghue C, Ozanne EM

Making better doctors: a survey of premedical interns working as health coaches.

Journal of cancer education : the official journal of the American Association for Cancer Education

Zarin-Pass M, Belkora J, Volz S, Esserman L

Abstract 124: outcomes of total skin-sparing mastectomy and reconstruction in 924 breasts over 11 years.

Plastic and reconstructive surgery

Wang F, Peled A, Foster R, Wang E, Ewing C, Alvarado M, Esserman L, Sbitany H

Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.

Cancer

Jackson SA, Davis AA, Li J, Yi N, McCormick SR, Grant C, Fallen T, Crawford B, Loranger K, Litton J, Arun B, Vande Wydeven K, Sidani A, Farmer K, Sanders M, Hoskins K, Nussbaum R, Esserman L, Garber JE, Kaklamani VG

Mammographic screening detects low-risk tumor biology breast cancers.

Breast cancer research and treatment

Drukker CA, Schmidt MK, Rutgers EJ, Cardoso F, Kerlikowske K, Esserman LJ, van Leeuwen FE, Pijnappel RM, Slaets L, Bogaerts J, Van't Veer LJ

Development of a personalized decision aid for breast cancer risk reduction and management.

BMC medical informatics and decision making

Ozanne EM, Howe R, Omer Z, Esserman LJ

Changing the terminology of cancer--reply.

JAMA

Esserman LJ, Thompson IM, Reid BJ

Optimized breast MRI functional tumor volume as a biomarker of recurrence-free survival following neoadjuvant chemotherapy.

Journal of magnetic resonance imaging : JMRI

Jafri NF, Newitt DC, Kornak J, Esserman LJ, Joe BN, Hylton NM

Evolving paradigm for imaging, diagnosis, and management of DCIS.

Journal of the American College of Radiology : JACR

Wells CJ, O'Donoghue C, Ojeda-Fournier H, Retallack HE, Esserman LJ

Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery.

Breast cancer research and treatment

Alvarado MD, Conolly J, Park C, Sakata T, Mohan AJ, Harrison BL, Hayes M, Esserman LJ, Ozanne EM

Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial.

Lancet (London, England)

Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Keshtgar M, Flyger HL, Massarut S, Alvarado M, Saunders C, Eiermann W, Metaxas M, Sperk E, Sütterlin M, Brown D, Esserman L, Roncadin M, Thompson A, Dewar JA, Holtveg HM, Pigorsch S, Falzon M, Harris E, Matthews A, Brew-Graves C, Potyka I, Corica T, Williams NR, Baum M

Screening: biology dictates the fate of young women with breast cancer.

Nature reviews. Clinical oncology

Eklund M, Esserman LJ

The prognostic implications of macrophages expressing proliferating cell nuclear antigen in breast cancer depend on immune context.

PloS one

Campbell MJ, Wolf D, Mukhtar RA, Tandon V, Yau C, Au A, Baehner F, van't Veer L, Berry D, Esserman LJ

Impact of ductal carcinoma in situ terminology on patient treatment preferences.

JAMA internal medicine

Omer ZB, Hwang ES, Esserman LJ, Howe R, Ozanne EM

Total skin-sparing mastectomy in BRCA mutation carriers.

Annals of surgical oncology

Peled AW, Irwin CS, Hwang ES, Ewing CA, Alvarado M, Esserman LJ

The Athena Breast Health Network: developing a rapid learning system in breast cancer prevention, screening, treatment, and care.

Breast cancer research and treatment

Elson SL, Hiatt RA, Anton-Culver H, Howell LP, Naeim A, Parker BA, Van't Veer LJ, Hogarth M, Pierce JP, Duwors RJ, Hajopoulos K, Esserman LJ

Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer.

Annals of surgical oncology

Alvarado MD, Mohan AJ, Esserman LJ, Park CC, Harrison BL, Howe RJ, Thorsen C, Ozanne EM

Reducing false-positive biopsies: a pilot study to reduce benign biopsy rates for BI-RADS 4A/B assessments through testing risk stratification and new thresholds for intervention.

Breast cancer research and treatment

Flowers CI, O'Donoghue C, Moore D, Goss A, Kim D, Kim JH, Elias SG, Fridland J, Esserman LJ

Total skin-sparing mastectomy: a systematic review of oncologic outcomes and postoperative complications.

Annals of plastic surgery

Piper M, Peled AW, Foster RD, Moore DH, Esserman LJ

Developing safety criteria for introducing new agents into neoadjuvant trials.

Clinical cancer research : an official journal of the American Association for Cancer Research

DeMichele A, Berry DA, Zujewski J, Hunsberger S, Rubinstein L, Tomaszewski JE, Kelloff G, Perlmutter J, Buxton M, Lyandres J, Albain KS, Benz C, Chien AJ, Haluska P, Leyland-Jones B, Liu MC, Munster P, Olopade O, Park JW, Parker BA, Pusztai L, Tripathy D, Rugo H, Yee D, Esserman L

An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.

Breast cancer research : BCR

Yau C, Sninsky J, Kwok S, Wang A, Degnim A, Ingle JN, Gillett C, Tutt A, Waldman F, Moore D, Esserman L, Benz CC

Physician behaviors surrounding the implementation of decision and communication AIDS in a breast cancer clinic: a qualitative analysis of staff intern perceptions.

Journal of cancer education : the official journal of the American Association for Cancer Education

Pass M, Volz S, Teng A, Esserman L, Belkora J

Will early detection for breast cancer ever work?

Clinical chemistry

Esserman L, Ozanne E, van't Veer L

Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Yee D, Haddad T, Albain K, Barker A, Benz C, Boughey J, Buxton M, Chien AJ, DeMichele A, Dilts D, Elias A, Haluska P, Hogarth M, Hu A, Hytlon N, Kaplan HG, Kelloff GG, Khan Q, Lang J, Leyland-Jones B, Liu M, Nanda R, Northfelt D, Olopade OI, Park J, Parker B, Parkinson D, Pearson-White S, Perlmutter J, Pusztai L, Symmans F, Rugo H, Tripathy D, Wallace A, Wholley D, Van't Veer L, Berry DA, Esserman L

Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Khatcheressian JL, Hurley P, Bantug E, Esserman LJ, Grunfeld E, Halberg F, Hantel A, Henry NL, Muss HB, Smith TJ, Vogel VG, Wolff AC, Somerfield MR, Davidson NE

Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.

Clinical cancer research : an official journal of the American Association for Cancer Research

Wulfkuhle JD, Berg D, Wolff C, Langer R, Tran K, Illi J, Espina V, Pierobon M, Deng J, DeMichele A, Walch A, Bronger H, Becker I, Waldhör C, Höfler H, Esserman L

Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.

Breast cancer research and treatment

Lips EH, Mukhtar RA, Yau C, de Ronde JJ, Livasy C, Carey LA, Loo CE, Vrancken-Peeters MJ, Sonke GS, Berry DA, Van't Veer LJ, Esserman LJ, Wesseling J, Rodenhuis S, Shelley Hwang E

Increasing the time to expander-implant exchange after postmastectomy radiation therapy reduces expander-implant failure.

Plastic and reconstructive surgery

Peled AW, Foster RD, Esserman LJ, Park CC, Hwang ES, Fowble B

Breast cancer screening: the questions answered.

Nature reviews. Clinical oncology

Autier P, Esserman LJ, Flowers CI, Houssami N

The impact of an electronic health questionnaire on symptom management and behavior reporting for breast cancer survivors.

Breast cancer research and treatment

Bock M, Moore D, Hwang J, Shumay D, Lawson L, Hamolsky D, Esserman L, Rugo H, Chien AJ, Park J, Munster P, Melisko M

Adoption, acceptability, and accuracy of an online clinical trial matching website for breast cancer.

Journal of medical Internet research

Cohen E, Belkora J, Tyler J, Schreiner J, Deering MJ, Grama L, Duggan B, Illi J, Pederson J, Anand A, Teng A, McCreary E, Moore D, Tripathy D, Hogarth M, Lieberman M, Park J, Esserman L

Biology of breast cancer in Nigerian women: a pilot study.

Annals of African medicine

Adisa CA, Eleweke N, Alfred AA, Campbell MJ, Sharma R, Nseyo O, Tandon V, Mukhtar R, Greninger A, Risi JD, Esserman LJ

Whole-genome analysis informs breast cancer response to aromatase inhibition.

Nature

Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, Weber J, Chen K, Koboldt DC, Kandoth C, Schierding WS, McMichael JF, Miller CA, Lu C, Harris CC, McLellan MD, Wendl MC, DeSchryver K, Allred DC, Esserman L, Unzeitig G, Margenthaler J, Babiera GV, Marcom PK, Guenther JM, Leitch M, Hunt K, Olson J, Tao Y, Maher CA, Fulton LL, Fulton RS, Harrison M, Oberkfell B, Du F, Demeter R, Vickery TL, Elhammali A, Piwnica-Worms H, McDonald S, Watson M, Dooling DJ, Ota D, Chang LW, Bose R, Ley TJ, Piwnica-Worms D, Stuart JM, Wilson RK, Mardis ER

Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy--results from ACRIN 6657/I-SPY TRIAL.

Radiology

Hylton NM, Blume JD, Bernreuter WK, Pisano ED, Rosen MA, Morris EA, Weatherall PT, Lehman CD, Newstead GM, Polin S, Marques HS, Esserman LJ, Schnall MD

The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy: results of a prospective practice improvement study.

Plastic and reconstructive surgery

Peled AW, Foster RD, Garwood ER, Moore DH, Ewing CA, Alvarado M, Hwang ES, Esserman LJ

Evaluating the feasibility of extended partial mastectomy and immediate reduction mammoplasty reconstruction as an alternative to mastectomy.

Annals of surgery

Chang EI, Peled AW, Foster RD, Lin C, Zeidler KR, Ewing CA, Alvarado M, Hwang ES, Esserman LJ

A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints.

The Lancet. Oncology

Fumagalli D, Bedard PL, Nahleh Z, Michiels S, Sotiriou C, Loi S, Sparano JA, Ellis M, Hylton N, Zujewski JA, Hudis C, Esserman L, Piccart M

Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Esserman LJ, Berry DA, DeMichele A, Carey L, Davis SE, Buxton M, Hudis C, Gray JW, Perou C, Yau C, Livasy C, Krontiras H, Montgomery L, Tripathy D, Lehman C, Liu MC, Olopade OI, Rugo HS, Carpenter JT, Dressler L, Chhieng D, Singh B, Mies C, Rabban J, Chen YY, Giri D, van 't Veer L, Hylton N

Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.

Annals of surgical oncology

Mukhtar RA, Moore AP, Tandon VJ, Nseyo O, Twomey P, Adisa CA, Eleweke N, Au A, Baehner FL, Moore DH, McGrath MS, Olopade OI, Gray JW, Campbell MJ, Esserman LJ

Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts.

Annals of surgical oncology

Warren Peled A, Foster RD, Stover AC, Itakura K, Ewing CA, Alvarado M, Hwang ES, Esserman LJ

MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition.

The Journal of experimental medicine

Horiuchi D, Kusdra L, Huskey NE, Chandriani S, Lenburg ME, Gonzalez-Angulo AM, Creasman KJ, Bazarov AV, Smyth JW, Davis SE, Yaswen P, Mills GB, Esserman LJ, Goga A

Targeting Molecular Aberrations in Breast Cancer: Is It about Time?

American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting

Esserman L, Benz C, Demichele A

Overdiagnosis and overtreatment of breast cancer.

American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting

Alvarado M, Ozanne E, Esserman L

Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).

Breast cancer research and treatment

Esserman LJ, Berry DA, Cheang MC, Yau C, Perou CM, Carey L, DeMichele A, Gray JW, Conway-Dorsey K, Lenburg ME, Buxton MB, Davis SE, van't Veer LJ, Hudis C, Chin K, Wolf D, Krontiras H, Montgomery L, Tripathy D, Lehman C, Liu MC, Olopade OI, Rugo HS, Carpenter JT, Livasy C, Dressler L, Chhieng D, Singh B, Mies C, Rabban J, Chen YY, Giri D, Au A, Hylton N

Proposals for uniform collection of biospecimens from neoadjuvant breast cancer clinical trials: timing and specimen types.

The Lancet. Oncology

Loi S, Symmans WF, Bartlett JM, Fumagalli D, Van't Veer L, Forbes JF, Bedard P, Denkert C, Zujewski J, Viale G, Pusztai L, Esserman LJ, Leyland-Jones BR

Impact of mammographic screening on the detection of good and poor prognosis breast cancers.

Breast cancer research and treatment

Esserman LJ, Shieh Y, Rutgers EJ, Knauer M, Retèl VP, Mook S, Glas AM, Moore DH, Linn S, van Leeuwen FE, van 't Veer LJ

Outcome of long term active surveillance for estrogen receptor-positive ductal carcinoma in situ.

Breast (Edinburgh, Scotland)

Meyerson AF, Lessing JN, Itakura K, Hylton NM, Wolverton DE, Joe BN, Esserman LJ, Hwang ES

Leukocyte composition of human breast cancer.

Proceedings of the National Academy of Sciences of the United States of America

Ruffell B, Au A, Rugo HS, Esserman LJ, Hwang ES, Coussens LM

Locally advanced breast cancers are more likely to present as Interval Cancers: results from the I-SPY 1 TRIAL (CALGB 150007/150012, ACRIN 6657, InterSPORE Trial).

Breast cancer research and treatment

Lin C, Buxton MB, Moore D, Krontiras H, Carey L, DeMichele A, Montgomery L, Tripathy D, Lehman C, Liu M, Olapade O, Yau C, Berry D, Esserman LJ

Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicity.

Breast cancer research and treatment

Mukhtar RA, Moore AP, Nseyo O, Baehner FL, Au A, Moore DH, Twomey P, Campbell MJ, Esserman LJ

Biologic markers determine both the risk and the timing of recurrence in breast cancer.

Breast cancer research and treatment

Esserman LJ, Moore DH, Tsing PJ, Chu PW, Yau C, Ozanne E, Chung RE, Tandon VJ, Park JW, Baehner FL, Kreps S, Tutt AN, Gillett CE, Benz CC

A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.

JAMA

Hatzis C, Pusztai L, Valero V, Booser DJ, Esserman L, Lluch A, Vidaurre T, Holmes F, Souchon E, Wang H, Martin M, Cotrina J, Gomez H, Hubbard R, Chacón JI, Ferrer-Lozano J, Dyer R, Buxton M, Gong Y, Wu Y, Ibrahim N, Andreopoulou E, Ueno NT, Hunt K, Yang W, Nazario A, DeMichele A, O'Shaughnessy J, Hortobagyi GN, Symmans WF

Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based int

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ellis MJ, Suman VJ, Hoog J, Lin L, Snider J, Prat A, Parker JS, Luo J, DeSchryver K, Allred DC, Esserman LJ, Unzeitig GW, Margenthaler J, Babiera GV, Marcom PK, Guenther JM, Watson MA, Leitch M, Hunt K, Olson JA

Characterizing the impact of 25 years of DCIS treatment.

Breast cancer research and treatment

Ozanne EM, Shieh Y, Barnes J, Bouzan C, Hwang ES, Esserman LJ

The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ.

Clinical breast cancer

Itakura K, Lessing J, Sakata T, Heinzerling A, Vriens E, Wisner D, Alvarado M, Esserman L, Ewing C, Hylton N, Hwang ES

Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics.

Expert review of molecular diagnostics

Mukhtar RA, Nseyo O, Campbell MJ, Esserman LJ

A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.

Breast cancer research : BCR

Yau C, Esserman L, Moore DH, Waldman F, Sninsky J, Benz CC

The Communication and Care Plan: a novel approach to patient-centered clinical information systems.

Journal of biomedical informatics

Hogarth M, Hajopoulos K, Young M, Cowles N, Churin J, Hornthal B, Esserman L

Long-term prognostic role of functional limitations among women with breast cancer.

Journal of the National Cancer Institute

Braithwaite D, Satariano WA, Sternfeld B, Hiatt RA, Ganz PA, Kerlikowske K, Moore DH, Slattery ML, Tammemagi M, Castillo A, Melisko M, Esserman L, Weltzien EK, Caan BJ

Intraoperative frozen section analysis of sentinel lymph nodes in breast cancer patients: a meta-analysis and single-institution experience.

Cancer

Liu LC, Lang JE, Lu Y, Roe D, Hwang SE, Ewing CA, Esserman LJ, Morita E, Treseler P, Leong SP

Impact of chemotherapy on postoperative complications after mastectomy and immediate breast reconstruction.

Archives of surgery (Chicago, Ill. : 1960)

Warren Peled A, Itakura K, Foster RD, Hamolsky D, Tanaka J, Ewing C, Alvarado M, Esserman LJ, Hwang ES

Lessons learned from genetic testing.

JAMA

Esserman L, Kaklamani V

Expanding the reach of decision and communication aids in a breast care center: a quality improvement study.

Patient education and counseling

Belkora JK, Teng A, Volz S, Loth MK, Esserman LJ

Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.

Lancet (London, England)

Vaidya JS, Joseph DJ, Tobias JS, Bulsara M, Wenz F, Saunders C, Alvarado M, Flyger HL, Massarut S, Eiermann W, Keshtgar M, Dewar J, Kraus-Tiefenbacher U, Sütterlin M, Esserman L, Holtveg HM, Roncadin M, Pigorsch S, Metaxas M, Falzon M, Matthews A, Corica T, Williams NR, Baum M

Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins?

International journal of radiation oncology, biology, physics

Chan LW, Rabban J, Hwang ES, Bevan A, Alvarado M, Ewing C, Esserman L, Fowble B

Solving the overdiagnosis dilemma.

Journal of the National Cancer Institute

Esserman L, Thompson I

Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.

Breast cancer research and treatment

Garwood ER, Kumar AS, Baehner FL, Moore DH, Au A, Hylton N, Flowers CI, Garber J, Lesnikoski BA, Hwang ES, Olopade O, Port ER, Campbell M, Esserman LJ

Application of screening principles to the reconstructed breast.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Zakhireh J, Fowble B, Esserman LJ

Bacteriologic features of surgical site infections following breast surgery.

American journal of surgery

Mukhtar RA, Throckmorton AD, Alvarado MD, Ewing CA, Esserman LJ, Chiu C, Hwang ES

Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ.

BMC cancer

Chen YY, DeVries S, Anderson J, Lessing J, Swain R, Chin K, Shim V, Esserman LJ, Waldman FM, Hwang ES

A comparison of RNA amplification techniques at sub-nanogram input concentration.

BMC genomics

Lang JE, Magbanua MJ, Scott JH, Makrigiorgos GM, Wang G, Federman S, Esserman LJ, Park JW, Haqq CM

I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy.

Clinical pharmacology and therapeutics

Barker AD, Sigman CC, Kelloff GJ, Hylton NM, Berry DA, Esserman LJ

Improved surgical outcomes for breast cancer patients receiving neoadjuvant aromatase inhibitor therapy: results from a multicenter phase II trial.

Journal of the American College of Surgeons

Olson JA, Budd GT, Carey LA, Harris LA, Esserman LJ, Fleming GF, Marcom PK, Leight GS, Giuntoli T, Commean P, Bae K, Luo J, Ellis MJ

Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer.

The breast journal

Lang JE, Liu LC, Lu Y, Jenkins T, Hwang SE, Esserman LJ, Ewing CA, Alvarado M, Morita E, Treseler P, Leong SP

The UCSC Cancer Genomics Browser.

Nature methods

Zhu J, Sanborn JZ, Benz S, Szeto C, Hsu F, Kuhn RM, Karolchik D, Archie J, Lenburg ME, Esserman LJ, Kent WJ, Haussler D, Wang T

Hypertension is an independent predictor of survival disparity between African-American and white breast cancer patients.

International journal of cancer. Journal international du cancer

Braithwaite D, Tammemagi CM, Moore DH, Ozanne EM, Hiatt RA, Belkora J, West DW, Satariano WA, Liebman M, Esserman L

Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients.

Annals of surgery

Garwood ER, Moore D, Ewing C, Hwang ES, Alvarado M, Foster RD, Esserman LJ

When informed, all women do not prefer breast conservation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Throckmorton AD, Esserman LJ

Sensitivity to input variability of the Adjuvant! Online breast cancer prognostic model.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ozanne EM, Braithwaite D, Sepucha K, Moore D, Esserman L, Belkora J

Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.

BMC cancer

Tutt A, Wang A, Rowland C, Gillett C, Lau K, Chew K, Dai H, Kwok S, Ryder K, Shu H, Springall R, Cane P, McCallie B, Kam-Morgan L, Anderson S, Buerger H, Gray J, Bennington J, Esserman L, Hastie T, Broder S, Sninsky J, Brandt B, Waldman F

Converting evidence to practice: a guide for the clinical application of MRI for the screening and management of breast cancer.

European journal of cancer (Oxford, England : 1990)

Zakhireh J, Gomez R, Esserman L

Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer?

Journal of the American College of Surgeons

Liu LC, Lang JE, Jenkins T, Lu Y, Ewing CA, Hwang SE, Sokol S, Alvarado M, Esserman LJ, Morita E, Treseler P, Leong SP

Monitoring the implementation of Consultation Planning, Recording, and Summarizing in a breast care center.

Patient education and counseling

Belkora JK, Loth MK, Chen DF, Chen JY, Volz S, Esserman LJ

Risk communication with patients with breast cancer: cautionary notes about printing Adjuvant! estimates.

The Lancet. Oncology

Belkora J, Rugo HS, Moore DH, Hutton D, Esserman L

Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Kumar AS, Benz CC, Shim V, Minami CA, Moore DH, Esserman LJ

Statement of the science concerning locoregional treatments after preoperative chemotherapy for breast cancer: a National Cancer Institute conference.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Buchholz TA, Lehman CD, Harris JR, Pockaj BA, Khouri N, Hylton NF, Miller MJ, Whelan T, Pierce LJ, Esserman LJ, Newman LA, Smith BL, Bear HD, Mamounas EP

Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.

Journal of proteome research

Wulfkuhle JD, Speer R, Pierobon M, Laird J, Espina V, Deng J, Mammano E, Yang SX, Swain SM, Nitti D, Esserman LJ, Belluco C, Liotta LA, Petricoin EF

Optimizing the total skin-sparing mastectomy.

Archives of surgery (Chicago, Ill. : 1960)

Wijayanayagam A, Kumar AS, Foster RD, Esserman LJ

A role for biomarkers in the screening and diagnosis of breast cancer in younger women.

Expert review of molecular diagnostics

Esserman LJ, Shieh Y, Park JW, Ozanne EM

Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Park JW, Melisko ME, Esserman LJ, Jones LA, Wollan JB, Sims R

Fluorescence in situ hybridization of ductal lavage samples identifies malignant phenotypes from cytologically normal cells in women with breast cancer.

Cancer

Adduci KM, Annis CE, DeVries S, Chew KL, Boutin J, Magrane G, Ljung BM, Waldman FM, Esserman LJ

Pilot trial of a computerized decision aid for breast cancer prevention.

The breast journal

Ozanne EM, Annis C, Adduci K, Showstack J, Esserman L

Ductal carcinoma in situ in BRCA mutation carriers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Hwang ES, McLennan JL, Moore DH, Crawford BB, Esserman LJ, Ziegler JL

Analysis of molecular inversion probe performance for allele copy number determination.

Genome Biology

Wang Y, Moorhead M, Karlin-Neumann G, Wang NJ, Ireland J, Lin S, Chen C, Heiser LM, Chin K, Esserman L, Gray JW, Spellman PT, Faham M

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.

Cancer cell

Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL, Lapuk A, Neve RM, Qian Z, Ryder T, Chen F, Feiler H, Tokuyasu T, Kingsley C, Dairkee S, Meng Z, Chew K, Pinkel D, Jain A, Ljung BM, Esserman L, Albertson DG, Waldman FM, Gray JW

Type and duration of exogenous hormone use affects breast cancer histology.

Annals of surgical oncology

Kumar AS, Cureton E, Shim V, Sakata T, Moore DH, Benz CC, Esserman LJ, Hwang ES

Magnetic resonance imaging captures the biology of ductal carcinoma in situ.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Esserman LJ, Kumar AS, Herrera AF, Leung J, Au A, Chen YY, Moore DH, Chen DF, Hellawell J, Wolverton D, Hwang ES, Hylton NM

Biologic significance of false-positive magnetic resonance imaging enhancement in the setting of ductal carcinoma in situ.

American journal of surgery

Kumar AS, Chen DF, Au A, Chen YY, Leung J, Garwood ER, Gibbs J, Hylton N, Esserman LJ

Breast cancer growth prevention by statins.

Cancer research

Campbell MJ, Esserman LJ, Zhou Y, Shoemaker M, Lobo M, Borman E, Baehner F, Kumar AS, Adduci K, Marx C, Petricoin EF, Liotta LA, Winters M, Benz S, Benz CC

Evaluation of a visit preparation intervention implemented in two rural, underserved counties of Northern California.

Patient education and counseling

Belkora J, Katapodi M, Moore D, Franklin L, Hopper K, Esserman L

Clinical trials are required to prove the chemopreventive worth of statins.

Archives of internal medicine

Kumar AS, Benz CC, Esserman LJ

A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Kumar AS, Campbell M, Benz CC, Esserman LJ

Mammographic, sonographic, and pathologic characteristics of Burkitt's lymphoma in a patient referred for diagnostic mammography.

AJR. American journal of roentgenology

Esserman L, Sexton R, Yu QQ, Cabello-Inchausti B

Genetic/familial high-risk assessment: breast and ovarian.

Journal of the National Comprehensive Cancer Network : JNCCN

Daly MB, Axilbund JE, Bryant E, Buys S, Eng C, Friedman S, Esserman LJ, Farrell CD, Ford JM, Garber JE, Jeter JM, Kohlmann W, Lynch PM, Marcom PK, Nabell LM, Offit K, Osarogiagbon RU, Pasche B, Reiser G, Sutphen R, Weitzel JN

Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis.

Breast cancer research : BCR

Esserman LJ, Ozanne EM, Dowsett M, Slingerland JM

Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry.

JAMA

Nanda R, Schumm LP, Cummings S, Fackenthal JD, Sveen L, Ademuyiwa F, Cobleigh M, Esserman L, Lindor NM, Neuhausen SL, Olopade OI

Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer.

The breast journal

Tan YY, Wu CT, Fan YG, Hwang S, Ewing C, Lane K, Esserman L, Lu Y, Treseler P, Morita E, Leong SP

The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer.

Annals of surgical oncology

Fan YG, Tan YY, Wu CT, Treseler P, Lu Y, Chan CW, Hwang S, Ewing C, Esserman L, Morita E, Leong SP

Ratio of positive to total number of sentinel nodes predicts nonsentinel node status in breast cancer patients.

The breast journal

Tan YY, Fan YG, Lu Y, Hwang S, Ewing C, Esserman L, Morita E, Treseler P, Leong SP

MRI measurements of breast tumor volume predict response to neoadjuvant chemotherapy and recurrence-free survival.

AJR. American journal of roentgenology

Partridge SC, Gibbs JE, Lu Y, Esserman LJ, Tripathy D, Wolverton DS, Rugo HS, Hwang ES, Ewing CA, Hylton NM

Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Petricoin EF, Bichsel VE, Calvert VS, Espina V, Winters M, Young L, Belluco C, Trock BJ, Lippman M, Fishman DA, Sgroi DC, Munson PJ, Esserman LJ, Liotta LA

Immune dysfunction and micrometastases in women with breast cancer.

Breast cancer research and treatment

Campbell MJ, Scott J, Maecker HT, Park JW, Esserman LJ

Integration of imaging in the management of breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Esserman L

Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans.

Breast cancer research and treatment

Misell LM, Hwang ES, Au A, Esserman L, Hellerstein MK

Safety of immediate transverse rectus abdominis myocutaneous breast reconstruction for patients with locally advanced disease.

Archives of surgery (Chicago, Ill. : 1960)

Foster RD, Hansen SL, Esserman LJ, Hwang ES, Ewing C, Lane K, Anthony JP

Internal mammary sentinel lymph node mapping for invasive breast cancer: implications for staging and treatment.

The breast journal

Park C, Seid P, Morita E, Iwanaga K, Weinberg V, Quivey J, Hwang ES, Esserman LJ, Leong SP

Recruitment, genetic counseling, and BRCA testing for underserved women at a public hospital.

Genetic testing

Lee R, Beattie M, Crawford B, Mak J, Stewart N, Komaromy M, Esserman L, Shaw L, McLennan J, Strachowski L, Luce J, Ziegler J

Accuracy of selective sentinel lymphadenectomy after neoadjuvant chemotherapy: effect of clinical node status at presentation.

Journal of the American College of Surgeons

Lang JE, Esserman LJ, Ewing CA, Rugo HS, Lane KT, Leong SP, Hwang ES

Evaluation of breast cancer risk assessment techniques: a cost-effectiveness analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Ozanne EM, Esserman LJ

Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma.

Cancer

Hwang ES, Nyante SJ, Yi Chen Y, Moore D, DeVries S, Korkola JE, Esserman LJ, Waldman FM

Applying the neoadjuvant paradigm to ductal carcinoma in situ.

Annals of surgical oncology

Esserman L, Sepucha K, Ozanne E, Hwang ES

An XML message broker framework for exchange and integration of microarray data.

Bioinformatics (Oxford, England)

Tjandra D, Wong S, Shen W, Pulliam B, Yu E, Esserman L

Racial differences in mammographic breast density.

Cancer

del Carmen MG, Hughes KS, Halpern E, Rafferty E, Kopans D, Parisky YR, Sardi A, Esserman L, Rust S, Michaelson J

Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium.

Cancer research

Shim V, Gauthier ML, Sudilovsky D, Mantei K, Chew KL, Moore DH, Cha I, Tlsty TD, Esserman LJ

MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?

International immunology

Jabrane-Ferrat N, Nekrep N, Tosi G, Esserman L, Peterlin BM

Failure to harvest sentinel lymph nodes identified by preoperative lymphoscintigraphy in breast cancer patients.

The breast journal

Wu CT, Morita ET, Treseler PA, Esserman LJ, Hwang ES, Kuerer HM, Santos CL, Leong SP

Efficacy of computerized infrared imaging analysis to evaluate mammographically suspicious lesions.

AJR. American journal of roentgenology

Parisky YR, Sardi A, Hamm R, Hughes K, Esserman L, Rust S, Callahan K

Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy.

AJR. American journal of roentgenology

Partridge SC, Gibbs JE, Lu Y, Esserman LJ, Sudilovsky D, Hylton NM

Axillary metastasis from a malignant mullerian mixed tumor.

The breast journal

Cura MA, Blanco M, Esserman L

Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO.

Journal of the National Cancer Institute

Euhus DM, Smith KC, Robinson L, Stucky A, Olopade OI, Cummings S, Garber JE, Chittenden A, Mills GB, Rieger P, Esserman L, Crawford B, Hughes KS, Roche CA, Ganz PA, Seldon J, Fabian CJ, Klemp J, Tomlinson G

Consultation planning to help breast cancer patients prepare for medical consultations: effect on communication and satisfaction for patients and physicians.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Sepucha KR, Belkora JK, Mutchnick S, Esserman LJ

Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse.

In vitro cellular & developmental biology. Animal

Campbell MJ, Wollish WS, Lobo M, Esserman LJ

Improving the accuracy of mammography: volume and outcome relationships.

Journal of the National Cancer Institute

Esserman L, Cowley H, Eberle C, Kirkpatrick A, Chang S, Berbaum K, Gale A

Ductal lavage for detection of cellular atypia in women at high risk for breast cancer.

Journal of the National Cancer Institute

Dooley WC, Ljung BM, Veronesi U, Cazzaniga M, Elledge RM, O'Shaughnessy JA, Kuerer HM, Hung DT, Khan SA, Phillips RF, Ganz PA, Euhus DM, Esserman LJ, Haffty BG, King BL, Kelley MC, Anderson MM, Schmit PJ, Clark RR, Kass FC, Anderson BO, Troyan SL, Arias RD, Quiring JN, Love SM, Page DL, King EB

Does timely assessment affect the anxiety associated with an abnormal mammogram result?

Journal of women's health & gender-based medicine

Haas J, Kaplan C, McMillan A, Esserman LJ

MRI phenotype is associated with response to doxorubicin and cyclophosphamide neoadjuvant chemotherapy in stage III breast cancer.

Annals of surgical oncology

Esserman L, Kaplan E, Partridge S, Tripathy D, Rugo H, Park J, Hwang S, Kuerer H, Sudilovsky D, Lu Y, Hylton N

Ductal growth is impeded in mammary glands of C-neu transgenic mice.

Oncogene

Mukherjee S, Louie SG, Campbell M, Esserman L, Shyamala G

MR imaging of the breast in patients with positive margins after lumpectomy: influence of the time interval between lumpectomy and MR imaging.

AJR. American journal of roentgenology

Frei KA, Kinkel K, Bonel HM, Lu Y, Esserman LJ, Hylton NM

Integration of breast imaging into cancer management.

Current oncology reports

Esserman LJ, Wolverton D, Hylton N

Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability.

AJR. American journal of roentgenology

Kinkel K, Helbich TH, Esserman LJ, Barclay J, Schwerin EH, Sickles EA, Hylton NM

Current national health insurance coverage policies for breast and ovarian cancer prophylactic surgery.

Annals of surgical oncology

Kuerer HM, Hwang ES, Anthony JP, Dudley RA, Crawford B, Aubry WM, Esserman LJ

Building bridges between physicians and patients: results of a pilot study examining new tools for collaborative decision making in breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Sepucha KR, Belkora JK, Tripathy D, Esserman LJ

Management of ductal carcinoma in situ.

The Surgical clinics of North America

Hwang ES, Esserman LJ

Biological therapies for breast carcinoma: concepts for improvement in survival.

Seminars in oncology

Borden EC, Esserman L, Linder DJ, Campbell MJ, Fulton AM

Prophylactic mastectomy in women with a high risk of breast cancer.

The New England journal of medicine

Kuerer HM, Hwang ES, Esserman LJ

Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice.

Cancer immunology, immunotherapy : CII

Esserman LJ, Lopez T, Montes R, Bald LN, Fendly BM, Campbell MJ

Utility of magnetic resonance imaging in the management of breast cancer: evidence for improved preoperative staging.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Esserman L, Hylton N, Yassa L, Barclay J, Frankel S, Sickles E

A multicenter randomized trial of DIAC for cyclical mastopathy.

Primary care update for Ob/Gyns

Ballagh SA, Stover TL, Maragos TG, Reynolds MD, Wolfley GD, Esserman LJ, Herbst JR, Kirkegaard LW, Teichman SL

Is routine frozen section assessment feasible in the practice environment of the 1990s?

The cancer journal from Scientific American

Esserman L, Weidner N

Hormone replacement therapy and breast cancer risk.

Cancer practice

Burke CC, Gullatte MM, Vigliani M, Ruggiero RJ, Esserman L, Crawford B

Ultrasound tissue characterization of breast biopsy specimens: expanded study.

Ultrasonic imaging

Mortensen CL, Edmonds PD, Gorfu Y, Hill JR, Jensen JF, Schattner P, Shifrin LA, Valdes AD, Jeffrey SS, Esserman LJ

Barriers to care and treatment: the challenge of daily radiation therapy.

Cancer practice

Igoe S, Collins C, Hamolsky D, Esserman LJ

Should we recommend screening mammography for women aged 40 to 49?

Oncology (Williston Park, N.Y.)

Esserman L, Kerlikowske K

Trade-offs between survival and breast preservation for three initial treatments of ductal carcinoma-in-situ of the breast.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Hillner BE, Desch CE, Carlson RW, Smith TJ, Esserman L, Bear HD

Breast.

Pathology (Philadelphia, Pa.)

Weidner N, Esserman LJ

Cost per anomaly: what does a diaphragmatic hernia cost?

Journal of pediatric surgery

Metkus AP, Esserman L, Sola A, Harrison MR, Adzick NS

Follicular lymphoma: a model of lymphoid tumor progression in man.

Annals of oncology : official journal of the European Society for Medical Oncology / ESMO

Zelenetz AD, Campbell MJ, Bahler DW, Takahashi S, Oren R, Esserman L, Umetsu DT, Kwak LW, Maloney DG, Brown S

Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity.

Journal of immunology (Baltimore, Md. : 1950)

Campbell MJ, Esserman L, Byars NE, Allison AC, Levy R

Immunotherapy of established murine B cell lymphoma. Combination of idiotype immunization and cyclophosphamide.

Journal of immunology (Baltimore, Md. : 1950)

Campbell MJ, Esserman L, Levy R

Myocardial performance and extracellular ionized calcium in a severely failing human heart.

Annals of internal medicine

Ginsburg R, Esserman LJ, Bristow MR

A novel method for emergency immobilization of the wrist during cross-country skiing.

The American journal of sports medicine

Goldman MP, Esserman LJ, Bausback KN, Camargo CA, Nagel DA