Lena Winestone, MD

Assistant Adjunct Professor
Pediatrics

My research explores racial, ethnic, and socioeconomic disparities in access to care and outcome of leukemia and lymphoma treatment. I study access to care across the continuum of pediatric cancer from diagnosis and clinical trial enrollment through treatment and relapse to salvage therapies. My research has shown that African American children with acute lymphoblastic leukemia, acute myeloid leukemia, and mature B cell lymphoma are two times more likely to present with organ failure at the time of a new cancer diagnosis. My ongoing work investigates access to highly specialized and complex therapies such as stem cell transplant, chimeric antigen receptor T cells, and MIBG therapy.

Publications: 

Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas.

Cancer medicine

Penumarthy NL, Goldsby RE, Shiboski SC, Wustrack R, Murphy P, Winestone LE

The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation.

Pediatric blood & cancer

Friend BD, Bailey-Olson M, Melton A, Shimano KA, Kharbanda S, Higham C, Winestone LE, Huang J, Stieglitz E, Dvorak CC

Disparities in Survival and Health Outcomes in Childhood Leukemia.

Current hematologic malignancy reports

Winestone LE, Aplenc R

Disparities in pediatric acute myeloid leukemia (AML) clinical trial enrollment.

Leukemia & lymphoma

Winestone LE, Getz KD, Rao P, Li Y, Hall M, Huang YV, Seif AE, Fisher BT, Aplenc R

Hematopoietic Cell Transplantation in Young Adult Acute Lymphoblastic Leukemia: A United States Population-Level Analysis.

Journal of adolescent and young adult oncology

Muffly L, Li Q, Alvarez E, Kahn J, Winestone L, Cress R, Penn DC, Keegan THM

Renal Complications Associated with HSCT.

Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist

Lena E. Winestone, Alix E. Seif, Benjamin L. Laskin

High human herpesvirus 6 viral load in pediatric allogeneic hematopoietic stem cell transplant patients is associated with detection in end organs and high mortality.

Pediatric transplantation

Winestone LE, Punn R, Tamaresis JS, Buckingham J, Pinsky BA, Waggoner JJ, Kharbanda S

Complications preceding early deaths in Black and White children with acute myeloid leukemia.

Pediatric blood & cancer

Winestone LE, Getz KD, Miller TP, Li Y, Huang YS, Seif AE, Fisher BT, Aplenc R

Recurrent Donath-Landsteiner hemolytic anemia: a pediatric case report.

Transfusion

Prince SD, Winestone LE, Nance SJ, Friedman DF

The role of acuity of illness at presentation in early mortality in black children with acute myeloid leukemia.

American journal of hematology

Winestone LE, Getz KD, Miller TP, Wilkes JJ, Sack L, Li Y, Huang YS, Seif AE, Bagatell R, Fisher BT, Epstein AJ, Aplenc R

Increased utilization of pediatric specialty care: a population study of pediatric oncology inpatients in California.

Journal of pediatric hematology/oncology

Chamberlain LJ, Pineda N, Winestone L, Saynina O, Rangaswami A, Link M, Wise PH

Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons.

Clinical immunology (Orlando, Fla.)

Bernstein WB, Cox JH, Aronson NE, Tracy L, Schlienger K, Ratto-Kim S, Garner R, Cotte J, Zheng Z, Winestone L, Liebig C, Galley LM, Connors M, Birx DL, Carroll RG, Levine BL