Owen Wolkowitz, MD

Professor in Residence
Psychiatry
+1 415 476-7433
Publications: 

Posttraumatic stress disorder, symptoms, and white matter abnormalities among combat-exposed veterans.

Brain imaging and behavior

Aschbacher K, Mellon SH, Wolkowitz OM, Henn-Haase C, Yehuda R, Flory JD, Bierer LM, Abu-Amara D, Marmar CR, Mueller SG

Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals-preliminary findings.

Journal of psychosomatic research

Fair B, Mellon SH, Epel ES, Lin J, Révész D, Verhoeven JE, Penninx BW, Reus VI, Rosser R, Hough CM, Mahan L, Burke HM, Blackburn EH, Wolkowitz OM

Severity of anxiety- but not depression- is associated with oxidative stress in Major Depressive Disorder.

Journal of affective disorders

Steenkamp LR, Hough CM, Reus VI, Jain FA, Epel ES, James SJ, Morford AE, Mellon SH, Wolkowitz OM, Lindqvist D

Biological predictors of insulin resistance associated with posttraumatic stress disorder in young military veterans.

Psychoneuroendocrinology

Blessing EM, Reus V, Mellon SH, Wolkowitz OM, Flory JD, Bierer L, Lindqvist D, Dhabhar F, Li M, Qian M, Abu-Amara D, Galatzer-Levy I, Yehuda R, Marmar CR

Depression, telomeres and mitochondrial DNA: between- and within-person associations from a 10-year longitudinal study.

Molecular psychiatry

Verhoeven JE, Révész D, Picard M, Epel EE, Wolkowitz OM, Matthews KA, Penninx BW, Puterman E

Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression.

Psychoneuroendocrinology

Hough CM, Lindqvist D, Epel ES, Denis MS, Reus VI, Bersani FS, Rosser R, Mahan L, Burke HM, Wolkowitz OM, Mellon SH

Oxidative stress, inflammation and treatment response in major depression.

Psychoneuroendocrinology

Lindqvist D, Dhabhar FS, James SJ, Hough CM, Jain FA, Bersani FS, Reus VI, Verhoeven JE, Epel ES, Mahan L, Rosser R, Wolkowitz OM, Mellon SH

Unresolved Issues in Longitudinal Telomere Length Research: Response to Susser et al.

The American journal of psychiatry

Verhoeven JE, Lin J, Révész D, Wolkowitz OM, Penninx BW

Leukocyte telomere length: Effects of schizophrenia, age, and gender.

Journal of psychiatric research

Wolkowitz OM, Jeste DV, Martin AS, Lin J, Daly RE, Reuter C, Kraemer H

Increased pro-inflammatory milieu in combat related PTSD - A new cohort replication study.

Brain, behavior, and immunity

Lindqvist D, Dhabhar FS, Mellon SH, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Bersani FS, Marmar CR, Wolkowitz OM

The Association Between Psychiatric Disorders and Telomere Length: A Meta-Analysis Involving 14,827 Persons.

Psychosomatic medicine

Darrow SM, Verhoeven JE, Révész D, Lindqvist D, Penninx BW, Delucchi KL, Wolkowitz OM, Mathews CA

Cortisol/DHEA ratio and hippocampal volume: A pilot study in major depression and healthy controls.

Psychoneuroendocrinology

Jin RO, Mason S, Mellon SH, Epel ES, Reus VI, Mahan L, Rosser RL, Hough CM, Burke HM, Mueller SG, Wolkowitz OM

Leukocyte telomere length predicts SSRI response in major depressive disorder: A preliminary report.

Molecular neuropsychiatry

Hough CM, Bersani FS, Mellon SH, Epel ES, Reus VI, Lindqvist D, Lin J, Mahan L, Rosser R, Burke H, Coetzee J, Nelson JC, Blackburn EH, Wolkowitz OM

Elevated plasma F2-isoprostane levels in schizophrenia.

Schizophrenia research

Lee EE, Eyler LT, Wolkowitz OM, Martin AS, Reuter C, Kraemer H, Jeste DV

Alterations in leukocyte transcriptional control pathway activity associated with major depressive disorder and antidepressant treatment.

Translational psychiatry

Mellon SH, Wolkowitz OM, Schonemann MD, Epel ES, Rosser R, Burke HB, Mahan L, Reus VI, Stamatiou D, Liew CC, Cole SW

A population of atypical CD56(-)CD16(+) natural killer cells is expanded in PTSD and is associated with symptom severity.

Brain, behavior, and immunity

Bersani FS, Wolkowitz OM, Milush JM, Sinclair E, Eppling L, Aschbacher K, Lindqvist D, Yehuda R, Flory J, Bierer LM, Matokine I, Abu-Amara D, Reus VI, Coy M, Hough CM, Marmar CR, Mellon SH

Depressive and Anxiety Disorders Showing Robust, but Non-Dynamic, 6-Year Longitudinal Association With Short Leukocyte Telomere Length.

The American journal of psychiatry

Verhoeven JE, van Oppen P, Révész D, Wolkowitz OM, Penninx BW

Peripheral telomere length and hippocampal volume in adolescents with major depressive disorder.

Translational psychiatry

Henje Blom E, Han LK, Connolly CG, Ho TC, Lin J, LeWinn KZ, Simmons AN, Sacchet MD, Mobayed N, Luna ME, Paulus M, Epel ES, Blackburn EH, Wolkowitz OM, Yang TT

Association of dimensional psychological health measures with telomere length in male war veterans.

Journal of affective disorders

Bersani FS, Lindqvist D, Mellon SH, Epel ES, Yehuda R, Flory J, Henn-Hasse C, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM

Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation.

Brain, behavior, and immunity

Bersani FS, Wolkowitz OM, Lindqvist D, Yehuda R, Flory J, Bierer LM, Makotine I, Abu-Amara D, Coy M, Reus VI, Epel ES, Marmar C, Mellon SH

Evidence for disrupted gray matter structural connectivity in posttraumatic stress disorder.

Psychiatry research

Mueller SG, Ng P, Neylan T, Mackin S, Wolkowitz O, Mellon S, Yan X, Flory J, Yehuda R, Marmar CR, Weiner MW

Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals - Preliminary findings.

Psychoneuroendocrinology

Fair B, Mellon SH, Epel ES, Révész D, Verhoeven JE, Penninx BW, Reus VI, Mahan L, Hough C, Rosser R, Burke HM, Lin J, Blackburn EH, Wolkowitz OM

Telomerase activation as a possible mechanism of action for psychopharmacological interventions.

Drug discovery today

Bersani FS, Lindqvist D, Mellon SH, Penninx BW, Verhoeven JE, Révész D, Reus VI, Wolkowitz OM

Mitochondrial DNA copy number is reduced in male combat veterans with PTSD.

Progress in neuro-psychopharmacology & biological psychiatry

Bersani FS, Morley C, Lindqvist D, Epel ES, Picard M, Yehuda R, Flory J, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM, Mellon SH

A Preliminary Study: Efficacy of Mindfulness-Based Cognitive Therapy versus Sertraline as First-line Treatments for Major Depressive Disorder.

Mindfulness

Eisendrath SJ, Gillung E, Delucchi K, Mathalon DH, Yang TT, Satre DD, Rosser R, Sipe WE, Wolkowitz OM

Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.

Neuroscience and biobehavioral reviews

Lindqvist D, Epel ES, Mellon SH, Penninx BW, Révész D, Verhoeven JE, Reus VI, Lin J, Mahan L, Hough CM, Rosser R, Bersani FS, Blackburn EH, Wolkowitz OM

Is Post-Traumatic Stress Disorder Associated with Premature Senescence? A Review of the Literature.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Lohr JB, Palmer BW, Eidt CA, Aailaboyina S, Mausbach BT, Wolkowitz OM, Thorp SR, Jeste DV

Anxiety disorders and accelerated cellular ageing.

The British journal of psychiatry : the journal of mental science

Verhoeven JE, Révész D, van Oppen P, Epel ES, Wolkowitz OM, Penninx BW

Precuneal and amygdala spontaneous activity and functional connectivity in war-zone-related PTSD.

Psychiatry research

Yan X, Lazar M, Shalev AY, Neylan TC, Wolkowitz OM, Brown AD, Henn-Haase C, Yehuda R, Flory JD, Abu-Amara D, Sodickson DK, Marmar CR

Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects.

The American journal of psychiatry

Judd LL, Schettler PJ, Brown ES, Wolkowitz OM, Sternberg EM, Bender BG, Bulloch K, Cidlowski JA, de Kloet ER, Fardet L, Joëls M, Leung DY, McEwen BS, Roozendaal B, Van Rossum EF, Ahn J, Brown DW, Plitt A, Singh G

Telomere length and cortisol reactivity in children of depressed mothers.

Molecular psychiatry

Gotlib IH, LeMoult J, Colich NL, Foland-Ross LC, Hallmayer J, Joormann J, Lin J, Wolkowitz OM

Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings.

Psychiatry research

Lindqvist D, Mueller S, Mellon SH, Su Y, Epel ES, Reus VI, Rosser R, Mahan L, Mackin RS, Yang TT, Wolkowitz OM

Cellular aging in depression: Permanent imprint or reversible process?: An overview of the current evidence, mechanistic pathways, and targets for interventions.

BioEssays : news and reviews in molecular, cellular and developmental biology

Verhoeven JE, Révész D, Wolkowitz OM, Penninx BW

Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults.

Journal of affective disorders

Chen SH, Epel ES, Mellon SH, Lin J, Reus VI, Rosser R, Kupferman E, Burke H, Mahan L, Blackburn EH, Wolkowitz OM

Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress.

Brain, behavior, and immunity

Lindqvist D, Wolkowitz OM, Mellon S, Yehuda R, Flory JD, Henn-Haase C, Bierer LM, Abu-Amara D, Coy M, Neylan TC, Makotkine I, Reus VI, Yan X, Taylor NM, Marmar CR, Dhabhar FS

Dysregulated physiological stress systems and accelerated cellular aging.

Neurobiology of aging

Révész D, Verhoeven JE, Milaneschi Y, de Geus EJ, Wolkowitz OM, Penninx BW

Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study.

Molecular psychiatry

Verhoeven JE, Révész D, Epel ES, Lin J, Wolkowitz OM, Penninx BW

Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents.

Biological psychiatry

Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT

Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression.

Journal of the American Academy of Child and Adolescent Psychiatry

Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT

Spontaneous brain activity in combat related PTSD.

Neuroscience letters

Yan X, Brown AD, Lazar M, Cressman VL, Henn-Haase C, Neylan TC, Shalev A, Wolkowitz OM, Hamilton SP, Yehuda R, Sodickson DK, Weiner MW, Marmar CR

Stress and telomere biology: a lifespan perspective.

Psychoneuroendocrinology

Shalev I, Entringer S, Wadhwa PD, Wolkowitz OM, Puterman E, Lin J, Epel ES

Good stress, bad stress and oxidative stress: insights from anticipatory cortisol reactivity.

Psychoneuroendocrinology

Aschbacher K, O'Donovan A, Wolkowitz OM, Dhabhar FS, Su Y, Epel E

Dysregulated diurnal cortisol pattern is associated with glucocorticoid resistance in women with major depressive disorder.

Biological psychology

Jarcho MR, Slavich GM, Tylova-Stein H, Wolkowitz OM, Burke HM

Dysregulated relationship of inflammation and oxidative stress in major depression.

Brain, behavior, and immunity

Rawdin BJ, Mellon SH, Dhabhar FS, Epel ES, Puterman E, Su Y, Burke HM, Reus VI, Rosser R, Hamilton SP, Nelson JC, Wolkowitz OM

BDNF serum concentrations show no relationship with diagnostic group or medication status in neurodegenerative disease.

Current Alzheimer research

Woolley JD, Strobl EV, Shelly WB, Karydas AM, Robin Ketelle RN, Wolkowitz OM, Miller BL, Rankin KP

Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length.

Brain, behavior, and immunity

O'Donovan A, Tomiyama AJ, Lin J, Puterman E, Adler NE, Kemeny M, Wolkowitz OM, Blackburn EH, Epel ES

Does cellular aging relate to patterns of allostasis? An examination of basal and stress reactive HPA axis activity and telomere length.

Physiology & behavior

Tomiyama AJ, O'Donovan A, Lin J, Puterman E, Lazaro A, Chan J, Dhabhar FS, Wolkowitz O, Kirschbaum C, Blackburn E, Epel E

Maintenance of a positive outlook during acute stress protects against pro-inflammatory reactivity and future depressive symptoms.

Brain, behavior, and immunity

Aschbacher K, Epel E, Wolkowitz OM, Prather AA, Puterman E, Dhabhar FS

Higher fasting glucose levels are associated with reduced circulating angiogenic cell migratory capacity among healthy individuals.

American journal of cardiovascular disease

Aschbacher K, Chen Q, Varga M, Haddad DJ, Yeghiazarians Y, Epel E, Wolkowitz OM, Springer ML

Physical activity moderates effects of stressor-induced rumination on cortisol reactivity.

Psychosomatic medicine

Puterman E, O'Donovan A, Adler NE, Tomiyama AJ, Kemeny M, Wolkowitz OM, Epel E

Serum BDNF levels before treatment predict SSRI response in depression.

Progress in neuro-psychopharmacology & biological psychiatry

Wolkowitz OM, Wolf J, Shelly W, Rosser R, Burke HM, Lerner GK, Reus VI, Nelson JC, Epel ES, Mellon SH

Divergent trajectories of physical, cognitive, and psychosocial aging in schizophrenia.

Schizophrenia bulletin

Jeste DV, Wolkowitz OM, Palmer BW

Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder.

Biological psychiatry

O'Donovan A, Epel E, Lin J, Wolkowitz O, Cohen B, Maguen S, Metzler T, Lenoci M, Blackburn E, Neylan TC

Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.

PloS one

Wolkowitz OM, Mellon SH, Epel ES, Lin J, Dhabhar FS, Su Y, Reus VI, Rosser R, Burke HM, Kupferman E, Compagnone M, Nelson JC, Blackburn EH

Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response.

Molecular psychiatry

Wolkowitz OM, Mellon SH, Epel ES, Lin J, Reus VI, Rosser R, Burke H, Compagnone M, Nelson JC, Dhabhar FS, Blackburn EH

Of sound mind and body: depression, disease, and accelerated aging.

Dialogues in clinical neuroscience

Wolkowitz OM, Reus VI, Mellon SH

Intensive meditation training, immune cell telomerase activity, and psychological mediators.

Psychoneuroendocrinology

Jacobs TL, Epel ES, Lin J, Blackburn EH, Wolkowitz OM, Bridwell DA, Zanesco AP, Aichele SR, Sahdra BK, MacLean KA, King BG, Shaver PR, Rosenberg EL, Ferrer E, Wallace BA, Saron CD

Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline.

Brain research

Lin J, Kroenke CH, Epel E, Kenna HA, Wolkowitz OM, Blackburn E, Rasgon NL

Serum brain-derived neurotrophic factor predicts responses to escitalopram in chronic posttraumatic stress disorder.

Progress in neuro-psychopharmacology & biological psychiatry

Berger W, Mehra A, Lenoci M, Metzler TJ, Otte C, Tarasovsky G, Mellon SH, Wolkowitz OM, Marmar CR, Neylan TC

Depression gets old fast: do stress and depression accelerate cell aging?

Depression and anxiety

Wolkowitz OM, Epel ES, Reus VI, Mellon SH

Dynamics of telomerase activity in response to acute psychological stress.

Brain, behavior, and immunity

Epel ES, Lin J, Dhabhar FS, Wolkowitz OM, Puterman E, Karan L, Blackburn EH

Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance.

Journal of immunological methods

Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S, Blackburn E

Glucocorticoids. Mood, memory, and mechanisms.

Annals of the New York Academy of Sciences

Wolkowitz OM, Burke H, Epel ES, Reus VI

Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression.

Journal of psychiatric research

Dhabhar FS, Burke HM, Epel ES, Mellon SH, Rosser R, Reus VI, Wolkowitz OM

Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia?

Biological psychiatry

Vinogradov S, Fisher M, Holland C, Shelly W, Wolkowitz O, Mellon SH

Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women.

Brain, behavior, and immunity

O'Donovan A, Lin J, Tillie J, Tillie JM, Dhabhar FS, Wolkowitz OM, Wolkowitz O, Blackburn EH, Blackburn E, Epel ES, Epel E

Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).

Frontiers in neuroendocrinology

Maninger N, Wolkowitz OM, Reus VI, Epel ES, Mellon SH

When blue turns to grey: do stress and depression accelerate cell aging?

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Wolkowitz OM, Epel ES, Mellon S

Catecholamine response to methamphetamine is related to glucocorticoid levels but not to pleasurable subjective response.

Pharmacopsychiatry

Harris DS, Reus VI, Wolkowitz O, Jacob P, Everhart ET, Wilson M, Mendelson JE, Jones RT

Cell aging in relation to stress arousal and cardiovascular disease risk factors.

Psychoneuroendocrinology

Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbier C, Mendes WB, Blackburn EH

Repeated psychological stress testing in stimulant-dependent patients.

Progress in neuro-psychopharmacology & biological psychiatry

Harris DS, Reus VI, Wolkowitz OM, Mendelson JE, Jones RT

Reduced medial temporal lobe N-acetylaspartate in cognitively impaired but nondemented patients.

Neurology

Chao LL, Schuff N, Kramer JH, Du AT, Capizzano AA, O'Neill J, Wolkowitz OM, Jagust WJ, Chui HC, Miller BL, Yaffe K, Weiner MW

The "steroid dementia syndrome": an unrecognized complication of glucocorticoid treatment.

Annals of the New York Academy of Sciences

Wolkowitz OM, Lupien SJ, Bigler E, Levin RB, Canick J

Chronic pregnenolone effects in normal humans: attenuation of benzodiazepine-induced sedation.

Psychoneuroendocrinology

Meieran SE, Reus VI, Webster R, Shafton R, Wolkowitz OM

Hormonal changes with cholesterol reduction: a double-blind pilot study.

Journal of clinical pharmacy and therapeutics

Ormiston T, Wolkowitz OM, Reus VI, Johnson R, Manfredi F

Behavioral implications of lowering cholesterol levels: a double-blind pilot study.

Psychosomatics

Ormiston T, Wolkowitz OM, Reus VI, Manfredi F

Neurotransmitters, neurosteroids and neurotrophins: new models of the pathophysiology and treatment of depression.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Wolkowitz OM, Reus VI

Altering cortisol level does not change the pleasurable effects of methamphetamine in humans.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Harris DS, Reus VI, Wolkowitz OM, Mendelson JE, Jones RT

DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled study.

Neurology

Wolkowitz OM, Kramer JH, Reus VI, Costa MM, Yaffe K, Walton P, Raskind M, Peskind E, Newhouse P, Sack D, De Souza E, Sadowsky C, Roberts E

Benzodiazepines in schizophrenia: prefrontal cortex atrophy predicts clinical response to alprazolam augmentation.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Seeley WW, Turetsky N, Reus VI, Wolkowitz OM

Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Marco EJ, Wolkowitz OM, Vinogradov S, Poole JH, Lichtmacher J, Reus VI

Dehydroepiandrosterone supplementation and bone turnover in middle-aged to elderly men.

The Journal of clinical endocrinology and metabolism

Kahn AJ, Halloran B, Wolkowitz O, Brizendine L

Selective reduction of N-acetylaspartate in medial temporal and parietal lobes in AD.

Neurology

Schuff N, Capizzano AA, Du AT, Amend DL, O'Neill J, Norman D, Kramer J, Jagust W, Miller B, Wolkowitz OM, Yaffe K, Weiner MW

Antiglucocorticoid drugs in the treatment of depression.

Expert opinion on investigational drugs

Reus VI, Wolkowitz OM

Cortisol levels predict cognitive impairment induced by electroconvulsive therapy.

Biological psychiatry

Neylan TC, Canick JD, Hall SE, Reus VI, Sapolsky RM, Wolkowitz OM

Stress hormone-related psychopathology: pathophysiological and treatment implications.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Wolkowitz OM, Epel ES, Reus VI

Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

Harris DS, Wolkowitz OM, Reus VI

Treatment of depression with antiglucocorticoid drugs.

Psychosomatic medicine

Wolkowitz OM, Reus VI

Estrogen replacement therapy and cognitive decline in memory-impaired post-menopausal women.

Biological psychiatry

Costa MM, Reus VI, Wolkowitz OM, Manfredi F, Lieberman M

Antiglucocorticoid treatment of depression: double-blind ketoconazole.

Biological psychiatry

Wolkowitz OM, Reus VI, Chan T, Manfredi F, Raum W, Johnson R, Canick J

Double-blind treatment of major depression with dehydroepiandrosterone.

The American journal of psychiatry

Wolkowitz OM, Reus VI, Keebler A, Nelson N, Friedland M, Brizendine L, Roberts E

Selective alteration of personality and social behavior by serotonergic intervention.

The American journal of psychiatry

Knutson B, Wolkowitz OM, Cole SW, Chan T, Moore EA, Johnson RC, Terpstra J, Turner RA, Reus VI

Glucocorticoid medication, memory and steroid psychosis in medical illness.

Annals of the New York Academy of Sciences

Wolkowitz OM, Reus VI, Canick J, Levin B, Lupien S

Dehydroepiandrosterone (DHEA) treatment of depression.

Biological psychiatry

Wolkowitz OM, Reus VI, Roberts E, Manfredi F, Chan T, Raum WJ, Ormiston S, Johnson R, Canick J, Brizendine L, Weingartner H

Serotonergic intervention increases affiliative behavior in humans.

Annals of the New York Academy of Sciences

Knutson B, Cole S, Wolkowitz O, Reus V, Chan T, Moore E

Antiglucocorticoid treatments in psychiatry.

Psychoneuroendocrinology

Reus VI, Wolkowitz OM, Frederick S

The effects of clozapine on symptom reduction, neurocognitive function, and clinical management in treatment-refractory state hospital schizophrenic inpatients.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Hoff AL, Faustman WO, Wieneke M, Espinoza S, Costa M, Wolkowitz O, Csernansky JG

Dexamethasone for depression.

The American journal of psychiatry

Wolkowitz OM, Reus VI, Manfredi F, Chan T, Ormiston S, Johnson R

Novel strategies for treatment-resistant depression.

The Psychiatric clinics of North America

Hornig-Rohan M, Wolkowitz OM, Amsterdam JD

Human pharmacokinetics and tolerability of L-365,260, a novel cholecystokinin-B antagonist.

Journal of clinical pharmacology

Grasing K, Murphy MG, Lin J, Swigar M, Freedholm D, Clarke L, Zhang J, Wolkowitz OM, Weingartner H, Putnam K, Seibold JR

Antidepressant and cognition-enhancing effects of DHEA in major depression.

Annals of the New York Academy of Sciences

Wolkowitz OM, Reus VI, Roberts E, Manfredi F, Chan T, Ormiston S, Johnson R, Canick J, Brizendine L, Weingartner H

Beneficial effects of nalmefene augmentation in neuroleptic-stabilized schizophrenic patients.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Rapaport MH, Wolkowitz O, Kelsoe JR, Pato C, Konicki PE, Pickar D

Neuropsychiatric effects of anabolic steroids in male normal volunteers.

JAMA

Su TP, Pagliaro M, Schmidt PJ, Pickar D, Wolkowitz O, Rubinow DR

Rational polypharmacy in schizophrenia.

Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists

Wolkowitz OM

Steroid modulation of human memory: biochemical correlates.

Biological psychiatry

Wolkowitz OM, Weingartner H, Rubinow DR, Jimerson D, Kling M, Berretini W, Thompson K, Breier A, Doran A, Reus VI

Ketoconazole administration in hypercortisolemic depression.

The American journal of psychiatry

Wolkowitz OM, Reus VI, Manfredi F, Ingbar J, Brizendine L, Weingartner H

Quantitative electroencephalographic correlates of steroid administration in man.

Neuropsychobiology

Wolkowitz OM, Coppola R, Breier A, Doran AR, Rubinow DR, Berrettini WH, Kling MA, Pickar D

Plasma levels of catecholamines and corticotrophin during acute glucopenia induced by 2-deoxy-D-glucose in normal man.

Clinical autonomic research : official journal of the Clinical Autonomic Research Society

Goldstein DS, Breier A, Wolkowitz OM, Pickar D, Lenders JW

Benzodiazepine augmentation of neuroleptics in treatment-resistant schizophrenia.

Psychopharmacology bulletin

Wolkowitz OM, Turetsky N, Reus VI, Hargreaves WA

Antiglucocorticoid strategies in hypercortisolemic states.

Psychopharmacology bulletin

Wolkowitz OM, Reus VI, Manfredi F, Ingbar J, Brizendine L

Measurement and interpretation of changes in memory in response to drug treatments.

Psychopharmacology bulletin

Weingartner H, Eckardt M, Molchan S, Sunderland T, Wolkowitz O

Selective effects of triazolam on memory.

Psychopharmacology

Weingartner HJ, Hommer D, Lister RG, Thompson K, Wolkowitz O

Specificity of memory impairments with triazolam use.

Lancet (London, England)

Weingartner HJ, Eckardt MJ, Hommer DW, Mendelson W, Wolkowitz OM

Benzodiazepines in the treatment of schizophrenia: a review and reappraisal.

The American journal of psychiatry

Wolkowitz OM, Pickar D

MRI deep white matter hyperintensity in a psychiatric population.

Biological psychiatry

Deicken RF, Reus VI, Manfredi L, Wolkowitz OM

Drug trials and heterogeneity in schizophrenia: the mean is not the end.

Biological psychiatry

Wolkowitz OM, Bartko JJ, Pickar D

Plasma norepinephrine in chronic schizophrenia.

The American journal of psychiatry

Breier A, Wolkowitz OM, Roy A, Potter WZ, Pickar D

Cognitive effects of corticosteroids.

The American journal of psychiatry

Wolkowitz OM, Reus VI, Weingartner H, Thompson K, Breier A, Doran A, Rubinow D, Pickar D

Prednisone effects on neurochemistry and behavior. Preliminary findings.

Archives of general psychiatry

Wolkowitz OM, Rubinow D, Doran AR, Breier A, Berrettini WH, Kling MA, Pickar D

Hunger in humans induced by MK-329, a specific peripheral-type cholecystokinin receptor antagonist.

Biological psychiatry

Wolkowitz OM, Gertz B, Weingartner H, Beccaria L, Thompson K, Liddle RA

Cerebrospinal fluid and plasma monoamine metabolites and their relation to psychosis. Implications for regional brain dysfunction in schizophrenia.

Archives of general psychiatry

Pickar D, Breier A, Hsiao JK, Doran AR, Wolkowitz OM, Pato CN, Konicki PE, Potter WZ

Circadian variation of plasma homovanillic acid levels is attenuated by fluphenazine in patients with schizophrenia.

Archives of general psychiatry

Doran AR, Labarca R, Wolkowitz OM, Roy A, Douillet P, Pickar D

Suicidality and corticosteroid psychosis.

Biological psychiatry

Wolkowitz O

Prednisone effects on blood-brain barrier permeability and CNS IgG synthesis in healthy humans.

Psychoneuroendocrinology

Wolkowitz OM, Papadopoulos NM, Costello R, Breier A, Doran AR, Pickar D, Rubinow D

Neurochemical and neural mechanisms of positive and negative symptoms in schizophrenia.

Modern problems of pharmacopsychiatry

Pickar D, Litman RE, Konicki PE, Wolkowitz OM, Breier A

Models for research in consultation psychiatry.

Advances in psychosomatic medicine

Rubinow DR, Denicoff KD, Schmidt PJ, Wolkowitz OM, Joffe RT

Alprazolam augmentation of neuroleptics in schizophrenia.

The American journal of psychiatry

Wolkowitz OM, Breier A, Doran A, Lucas P, Kelsoe J, Paul SM, Pickar D

Specificity of plasma HVA response to dexamethasone in psychotic depression.

Psychiatry research

Wolkowitz OM, Doran A, Breier A, Roy A, Pickar D

High prevalence of visual hallucinations in research subjects with chronic schizophrenia.

The American journal of psychiatry

Bracha HS, Wolkowitz OM, Lohr JB, Karson CN, Bigelow LB

TRH test in schizophrenic patients and controls.

Biological psychiatry

Roy A, Wolkowitz O, Doran A, Pickar D

Fluphenazine treatment reduces CSF somatostatin in patients with schizophrenia: correlations with CSF HVA.

Biological psychiatry

Doran AR, Rubinow DR, Wolkowitz OM, Roy A, Breier A, Pickar D

Benzodiazepine augmentation of neuroleptic treatment in patients with schizophrenia.

Psychopharmacology bulletin

Pato CN, Wolkowitz OM, Rapaport M, Schulz SC, Pickar D

Early parental loss and development of adult psychopathology.

Archives of general psychiatry

Breier A, Kelsoe JR, Kirwin PD, Beller SA, Wolkowitz OM, Pickar D

Neurobiological effects of lumbar puncture stress in psychiatric patients and healthy volunteers.

Psychiatry research

Breier A, Wolkowitz OM, Doran AR, Bellar S, Pickar D

Single-dose naloxone acutely reduces eating in obese humans: behavioral and biochemical effects.

Biological psychiatry

Wolkowitz OM, Doran AR, Cohen MR, Cohen RM, Wise TN, Pickar D

Alprazolam augmentation of the antipsychotic effects of fluphenazine in schizophrenic patients. Preliminary results.

Archives of general psychiatry

Wolkowitz OM, Breier A, Doran A, Kelsoe J, Lucas P, Paul SM, Pickar D

Prednisone-induced behavioral and biological changes in medically healthy volunteers.

Psychopharmacology bulletin

Wolkowitz OM, Breier A, Doran A, Rubinow D, Berrettini W, Coppola R, Gold P, Pickar D

Alternate-day corticosteroid treatment, mood and plasma HVA in patients with systemic lupus erythematosus.

Neuropsychobiology

Joffe RT, Wolkowitz OM, Rubinow DR, Denicoff K, Tsokos G, Pillemer S

Metabolic stress effects in normal volunteers and schizophrenic patients.

Psychopharmacology bulletin

Breier A, Wolkowitz OM, Rapaport M, Paul SM, Pickar D

Neuroleptic responsivity of negative and positive symptoms in schizophrenia.

The American journal of psychiatry

Breier A, Wolkowitz OM, Doran AR, Roy A, Boronow J, Hommer DW, Pickar D

Dysphoria associated with methylphenidate infusion in borderline personality disorder.

The American journal of psychiatry

Lucas PB, Gardner DL, Wolkowitz OM, Cowdry RW

Metabolic stress produces rapid immunosuppression in humans.

Archives of general psychiatry

Breier A, Arora PK, Wolkowitz OM, Pickar D, Paul SM

Structural brain pathology in schizophrenia revisited. Prefrontal cortex pathology is inversely correlated with cerebrospinal fluid levels of homovanillic acid.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Doran AR, Boronow J, Weinberger DR, Wolkowitz OM, Breier A, Pickar D

Controllable and uncontrollable stress in humans: alterations in mood and neuroendocrine and psychophysiological function.

The American journal of psychiatry

Breier A, Albus M, Pickar D, Zahn TP, Wolkowitz OM, Paul SM

Prednisone decreases CSF somatostatin in healthy humans: implications for neuropsychiatric illness.

Life sciences

Wolkowitz OM, Rubinow DR, Breier A, Doran AR, Davis C, Pickar D

The effects of dexamethasone on plasma homovanillic acid and 3-methoxy-4-hydroxyphenylglycol. Evidence for abnormal corticosteroid-catecholamine interactions in major depression.

Archives of general psychiatry

Wolkowitz OM, Doran AR, Breier A, Roy A, Jimerson DC, Sutton ME, Golden RN, Paul SM, Pickar D

Clinical and biochemical effects of verapamil administration to schizophrenic patients.

Archives of general psychiatry

Pickar D, Wolkowitz OM, Doran AR, Labarca R, Roy A, Breier A, Narang PK

Biochemical alterations produced by neuroleptics in man: studies of plasma homovanillic acid in schizophrenic patients.

Psychopharmacology series

Pickar D, Wolkowitz OM, Labarca R, Doran AR, Breier A, Paul SM

Pharmacodynamic approaches to benzodiazepine action in man.

Psychopharmacology series

Hommer DW, Matsuo V, Wolkowitz OM, Weingartner H, Paul SM

Diazepam-induced amnesia: a neuropharmacological model of an "organic amnestic syndrome".

The American journal of psychiatry

Wolkowitz OM, Weingartner H, Thompson K, Pickar D, Paul SM, Hommer DW

Methylphenidate-induced cardiac arrhythmias.

The New England journal of medicine

Lucas PB, Gardner DL, Wolkowitz OM, Tucker EE, Cowdry RW

Serum antibodies to Epstein-Barr virus in patients with major depressive disorder.

The American journal of psychiatry

Amsterdam JD, Henle W, Winokur A, Wolkowitz OM, Pickar D, Paul SM

The corticotropin-releasing hormone stimulation test in chronic schizophrenia.

The American journal of psychiatry

Roy A, Pickar D, Doran A, Wolkowitz O, Gallucci W, Chrousos G, Gold P

Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment.

Archives of general psychiatry

Pickar D, Labarca R, Doran AR, Wolkowitz OM, Roy A, Breier A, Linnoila M, Paul SM

Benzodiazepine sensitivity in normal human subjects.

Archives of general psychiatry

Hommer DW, Matsuo V, Wolkowitz O, Chrousos G, Greenblatt DJ, Weingartner H, Paul SM

Chronic corticosterone administration in rats: behavioral and biochemical evidence of increased central dopaminergic activity.

European journal of pharmacology

Wolkowitz O, Sutton M, Koulu M, Labarca R, Wilkinson L, Doran A, Hauger R, Pickar D, Crawley J

Endogenous opioid regulation of hypothalamo-pituitary-adrenal axis activity in schizophrenia.

Biological psychiatry

Wolkowitz OM, Doran AR, Breier A, Cohen MR, Pickar D

Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls.

Journal of affective disorders

Roy A, Gold P, Pickar D, Wolkowitz OM, Chrousos G, Paul SM

Suicide and aggression in schizophrenia. Neurobiologic correlates.

Annals of the New York Academy of Sciences

Pickar D, Roy A, Breier A, Doran A, Wolkowitz O, Colison J, Agren H

Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia.

The American journal of psychiatry

Wolkowitz OM, Pickar D, Doran AR, Breier A, Tarell J, Paul SM

Dexamethasone increases plasma HVA but not MHPG in normal humans.

Psychiatry research

Wolkowitz OM, Sutton ME, Doran AR, Labarca R, Roy A, Thomas JW, Pickar D, Paul SM

Effect of naloxone on food consumption in obesity.

The New England journal of medicine

Wolkowitz OM, Doran AR, Cohen MR, Cohen RM, Wise TN, Pickar D

Pathologic gambling and other risk-taking pursuits.

The Psychiatric clinics of North America

Wolkowitz OM, Roy A, Doran AR

Self-destructive dermatoses.

The Psychiatric clinics of North America

Doran AR, Roy A, Wolkowitz OM

Verapamil concentrations in cerebrospinal fluid after oral administration.

The New England journal of medicine

Doran AR, Narang PK, Meigs CY, Wolkowitz OM, Roy A, Breier A, Pickar D

Neural and molecular mechanisms in anxiety.

The Psychiatric clinics of North America

Wolkowitz OM, Paul SM

A psychopharmacological perspective of cognitive functions. II. Specific pharmacologic agents.

Neuropsychobiology

Wolkowitz OM, Tinklenberg JR, Weingartner H

Evidence for a daily rhythm of plasma HVA in normal controls but not in schizophrenic patients.

Psychopharmacology bulletin

Doran AR, Pickar D, Labarca R, Douillet P, Wolkowitz OM, Thomas JW, Roy A, Paul SM

Development of differences in response latencies to right and left visual fields.

Brain and cognition

Stillman R, DeRenzo E, Wolkowitz O, Allen H, Lehman RA, Wyatt RJ

Marijuana: differential effects on right and left hemisphere functions in man.

Life sciences

Stillman RC, Wolkowitz O, Weingartner H, Waldman I, DeRenzo EV, Wyatt RJ