
Assoc Prof of Clin Pediatrics
M_PEDS-BONE MARROW TRANSPLANT
+1 415 476-2188
My research explores racial, ethnic, and socioeconomic disparities in access to care and outcome of leukemia and lymphoma treatment. I study access to care across the continuum of pediatric cancer from diagnosis and clinical trial enrollment through treatment and relapse to salvage therapies. My research has shown that African American children with acute lymphoblastic leukemia, acute myeloid leukemia, and mature B cell lymphoma are two times more likely to present with organ failure at the time of a new cancer diagnosis. My ongoing work investigates access to highly specialized and complex therapies such as stem cell transplant, chimeric antigen receptor T cells, and MIBG therapy.
Publications
Role of race and ethnicity in survival among children/young adults with relapsed ALL: a Children's Oncology Group report.
Blood advances
Real-World Outcomes of Infections Following Tisagenlecleucel in Patients with B-Cell ALL: A CIBMTR Analysis.
Blood advances
Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia.
Blood cancer discovery
Historical redlining and mortality in children, adolescents, and young adults with cancer in California, 2000-2019.
Journal of the National Cancer Institute
High Melphalan Exposure Increases the Risk of Graft-versus-Host Disease in Pediatric Patients Undergoing Alpha-Beta T-Cell Depleted Haploidentical Transplantation.
Transplantation and cellular therapy
Younger Children with Non-Malignant Disease Have Increased Incidence of Mixed Myeloid Chimerism After Allogeneic Hematopoietic Cell Transplantation with Busulfan-Based Conditioning.
Transplantation and cellular therapy
Fludarabine Pharmacokinetic-Model-Based Dosing Minimizes the Risk of Graft Rejection in Pediatric Patients Undergoing Mismatched Allogeneic Hematopoietic Cell Transplantation.
Transplantation and cellular therapy
High Exposure of Intravenous Alemtuzumab Is Associated with Increased Risk of Double-Stranded DNA Viral Infections in Patients with Non-Malignant Disease Undergoing Allogeneic HCT.
Transplantation and cellular therapy
Liberalizing Requirements for Hospital Proximity Post-CD19 CAR for Children with Low Burden B-ALL at Infusion.
Transplantation and cellular therapy
Real-World Assessment of Patient Adherence to the Late Effects Screening Recommendations Among Hematopoietic Cell Transplantation Survivors.
Transplantation and cellular therapy
Access to CARe: A Narrative of Real-World Medical Decision-Making to Access Chimeric Antigen Receptor (CAR) T-Cell Therapy in Children, Adolescents, and Young Adults.
Pediatric blood & cancer
Association of age, race, and ethnicity with access, response, and toxicities from CAR-T therapy in children and adults with B-cell malignancies: a review.
Journal for immunotherapy of cancer
Band-Aids Can Still Help Heal: The Role of Patient Financial Assistance Programs in Addressing Financial Toxicity.
JCO oncology practice
Impact of Race and Ethnicity on Outcomes after Umbilical Cord Blood Transplantation.
Transplantation and cellular therapy
Trends in Volumes and Survival After Hematopoietic Cell Transplantation in Racial/Ethnic Minorities.
Blood advances
Clinical trial recruitment of people who speak languages other than english: a children's oncology group report.
JNCI cancer spectrum
Cyclophosphamide and thiotepa increases risk of transplant-associated thrombotic microangiopathy.
Transplantation and cellular therapy
Time to diagnosis among young patients with cancer.
Pediatric blood & cancer
Diagnosing and Grading of Sinusoidal Obstructive Syndrome after Hematopoietic Stem Cell Transplant of Children, Adolescent and Young Adults treated in a Pediatric Institution with Pediatric Protocols.
Transplantation and cellular therapy
Intensive Care Risk and Long-Term Outcomes in Pediatric Allogeneic Hematopoietic Cell Transplant Recipients.
Blood advances
Establishing Costs for Commercial Chimeric Antigen Receptor T-Cell (Tisagenlecleucel; Kymriah) in Children and Young Adult B-Cell Acute Lymphoblastic Leukemia: A Merged Analysis from the Pediatric Real-World CAR Consortium (PRWCC) and Pediatric Health Inf
Transplantation and cellular therapy
Financial assistance and other financial coping strategies after a pediatric cancer diagnosis.
Pediatric blood & cancer
Pre- and post-natal exposures to tobacco smoking and survival of childhood acute lymphoblastic and myeloid leukemias in California, United States.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Unfavorable transcriptome profiles and social disadvantage in hematopoietic cell transplantation: a CIBMTR analysis.
Blood advances
Racial and ethnic disparities in acuity of presentation among children with newly diagnosed acute leukemia.
Pediatric blood & cancer
INSPIRED Symposium Part 4A: Access to CAR T cell Therapy in Unique Populations with B-cell Acute Lymphoblastic Leukemia.
Transplantation and cellular therapy
Practice preferences for consolidative HSCT following tisagenlecleucel in children and young adults with B-ALL.
Transplantation and cellular therapy
Children's Oncology Group's 2023 blueprint for research: Diversity and health disparities.
Pediatric blood & cancer
Subspecialty pediatrics: An unmet opportunity to address unmet social risks.
Academic pediatrics
Racial and Socioeconomic Disparities in Long-Term Outcomes in ≥1 Year Allogeneic Hematopoietic Cell Transplantation Survivors: A CIBMTR Analysis.
Transplantation and cellular therapy
Disparities in household material hardship, financial toxicity, and income loss in pediatric cancer.
Pediatric blood & cancer
Feasibility and acceptability of social determinants of health data collection in the context of a Children’s Oncology Group trial.
Journal of Clinical Oncology
Racial and Ethnic Disparities in Outcomes following Hematopoietic Stem Cell Transplant (HCT) in Patients with Severe Combined Immunodeficiency (SCID).
Clinical Immunology
Access to CAR T-cell Clinical Trials in Underrepresented Populations: a Multicenter Cohort Study of Pediatric and Young Adult ALL Patients.
Transplantation and cellular therapy
345 Prophylactic Tocilizumab Decreases Incidence of Acute Graft-Versus-Host Disease Following Alpha/Beta T-Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation in Children and Young Adults.
Transplantation and cellular therapy
Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia: secondary analyses of eight Children's Oncology Group cohort trials.
The Lancet. Haematology
Data standards in pediatric oncology: Past, present, and future.
Pediatric blood & cancer
Leveraging clinical trial populations and data from the Children's Oncology Group for cancer survivorship research.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Treatment-related toxicities associated with hospitalization in children, adolescents, and young adults with acute lymphoblastic leukemia: population level analysis.
Leukemia & lymphoma
Rates of laboratory adverse events by course in paediatric leukaemia ascertained with automated electronic health record extraction: a retrospective cohort study from the Children's Oncology Group.
The Lancet. Haematology
Clinical Characteristics and Outcomes of COVID-19 in Pediatric and Early Adolescent and Young Adult Haematopoietic Stem Cell Transplant Recipients: A Cohort Study.
Transplantation and cellular therapy
Outcomes of Hispanic and non-Hispanic white pediatric and young adult patients with B-cell acute lymphoblastic leukemia after commercial tisagenlecleucel.
Journal of Clinical Oncology
A pilot trial of prophylactic defibrotide to prevent serious thrombotic microangiopathy in high-risk pediatric patients.
Pediatric blood & cancer
Haploidentical vs. sibling, unrelated, or cord blood hematopoietic cell transplantation for acute lymphoblastic leukemia.
Blood advances
Hematopoietic Cell Transplant-Comorbidity Index Score is Correlated with Treatment Related Mortality and Overall Survival following Second Allogeneic Hematopoietic Cell Transplant in Children.
Transplantation and cellular therapy
Expenditures in Young Adults with Hodgkin Lymphoma: NCI-designated Comprehensive Cancer Centers vs. Other Sites.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Comorbidities and socioeconomic status are predictors of survival in children and young adults with Burkitt lymphoma.
Leukemia & lymphoma
Disparities in Pediatric Oncology: The 21st Century Opportunity to Improve Outcomes for Children and Adolescents With Cancer.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Chronic medical conditions and late effects after acute myeloid leukaemia in adolescents and young adults: a population-based study.
International journal of epidemiology
Transplant-associated thrombotic microangiopathy in pediatric patients: pre-HSCT risk stratification and prophylaxis.
Blood advances
Presentation acuity, induction mortality, and resource utilization in infants with acute leukemia.
Pediatric blood & cancer
Poverty and Targeted Immunotherapy: Survival in Children's Oncology Group Clinical Trials for High-Risk Neuroblastoma.
Journal of the National Cancer Institute
Adverse events among chronic myelogenous leukemia patients treated with tyrosine kinase inhibitors: a real-world analysis of health plan enrollees.
Leukemia & lymphoma
Impact of Dependent Coverage Provision of the Affordable Care Act on Insurance Continuity for Adolescents and Young Adults With Cancer.
JCO oncology practice
Health Care Cost Associated With Contemporary Chronic Myelogenous Leukemia Therapy Compared With That of Other Hematologic Malignancies.
JCO oncology practice
Identifying relapses and stem cell transplants in pediatric acute lymphoblastic leukemia using administrative data: Capturing national outcomes irrespective of trial enrollment.
Pediatric blood & cancer
Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas.
Cancer medicine
The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation.
Pediatric blood & cancer
50 Years Ago in TheJournal ofPediatrics: Fifty-Two Forms of Childhood Cancer, United States Mortality Experience, 1960-1966.
The Journal of pediatrics
Disparities in Survival and Health Outcomes in Childhood Leukemia.
Current hematologic malignancy reports
Disparities in pediatric acute myeloid leukemia (AML) clinical trial enrollment.
Leukemia & lymphoma
Hematopoietic Cell Transplantation in Young Adult Acute Lymphoblastic Leukemia: A United States Population-Level Analysis.
Journal of adolescent and young adult oncology
Comparable on-therapy mortality and supportive care requirements in Black and White patients following initial induction for pediatric acute myeloid leukemia.
Pediatric blood & cancer
Renal Complications Associated with HSCT.
Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist
High human herpesvirus 6 viral load in pediatric allogeneic hematopoietic stem cell transplant patients is associated with detection in end organs and high mortality.
Pediatric transplantation
Complications preceding early deaths in Black and White children with acute myeloid leukemia.
Pediatric blood & cancer
The role of acuity of illness at presentation in early mortality in black children with acute myeloid leukemia.
American journal of hematology
Increased utilization of pediatric specialty care: a population study of pediatric oncology inpatients in California.
Journal of pediatric hematology/oncology
Acceptability and feasibility of integration of HIV care services into antenatal clinics in rural Kenya: a qualitative provider interview study.
Global public health
Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons.
Clinical immunology (Orlando, Fla.)