Laura Jelliffe, PhD, MS

Associate Professor In Res
Epidemiology & Biostatistics

Dr. Laura Jelliffe-Pawlowski is an Associate Professor of Epidemiology & Biostatistics in the UCSF School of Medicine and is the Director of Precision Health and Discovery with the UCSF California Preterm Birth Initiative. Dr. Jelliffe-Pawlowski and her team work to identify new tools, tests and technologies that can help identify pregnant women and babies at increased risk for preterm birth and associated birth defects and developmental delays. She has a particular focus and interest in work that leverages serum-based markers to help predict outcomes and identify in-roads for intervention. Dr. Jelliffe-Pawlowski has served as a state, national, and international advisor on committees and task forces focused on the early detection and prevention of preterm birth and developmental disabilities. She leads a number of research projects in the United States and Africa.

Publications: 

Copy number variants in hypoplastic right heart syndrome.

American journal of medical genetics. Part A

Giannakou A, Sicko RJ, Kay DM, Zhang W, Romitti PA, Caggana M, Shaw GM, Jelliffe-Pawlowski LL, Mills JL

Combining newborn metabolic and DNA analysis for second-tier testing of methylmalonic acidemia.

Genetics in medicine : official journal of the American College of Medical Genetics

Peng G, Shen P, Gandotra N, Le A, Fung E, Jelliffe-Pawlowski L, Davis RW, Enns GM, Zhao H, Cowan TM, Scharfe C

Cross-Generational Contributors to Preterm Birth in California: Singletons Based on Race/Ethnicity.

American journal of perinatology

Francois LN, Yang J, Baer RJ, Chung PJ, Jelliffe-Pawlowski LL, Coker TR

Hypertensive Disorders of Pregnancy and Preterm Birth Rates among Black Women.

American journal of perinatology

Premkumar A, Baer RJ, Jelliffe-Pawlowski LL, Norton ME

Altered metabolites in newborns with persistent pulmonary hypertension.

Pediatric research

Steurer MA, Oltman S, Baer RJ, Feuer S, Liang L, Paynter RA, Rand L, Ryckman KK, Keller RL, Jelliffe-Pawlowski LL

Using Index of Concentration at the Extremes as Indicators of Structural Racism to Evaluate the Association with Preterm Birth and Infant Mortality-California, 2011-2012.

Journal of urban health : bulletin of the New York Academy of Medicine

Chambers BD, Baer RJ, McLemore MR, Jelliffe-Pawlowski LL

Prediction of preterm birth with and without preeclampsia using mid-pregnancy immune and growth-related molecular factors and maternal characteristics.

Journal of perinatology : official journal of the California Perinatal Association

Jelliffe-Pawlowski LL, Rand L, Bedell B, Baer RJ, Oltman SP, Norton ME, Shaw GM, Stevenson DK, Murray JC, Ryckman KK

Second trimester serum cortisol and preterm birth: an analysis by timing and subtype.

Journal of perinatology : official journal of the California Perinatal Association

Bandoli G, Jelliffe-Pawlowski LL, Feuer SK, Liang L, Oltman SP, Paynter R, Ross KM, Schetter CD, Ryckman KK, Chambers CD

Revisiting the Table 2 fallacy: A motivating example examining preeclampsia and preterm birth.

Paediatric and perinatal epidemiology

Bandoli G, Palmsten K, Chambers CD, Jelliffe-Pawlowski LL, Baer RJ, Thompson CA

Initial Metabolic Profiles Are Associated with 7-Day Survival among Infants Born at 22-25 Weeks of Gestation.

The Journal of pediatrics

Oltman SP, Rogers EE, Baer RJ, Anderson JG, Steurer MA, Pantell MS, Partridge JC, Rand L, Ryckman KK, Jelliffe-Pawlowski LL

Maternal factors influencing late entry into prenatal care: a stratified analysis by race or ethnicity and insurance status.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Baer RJ, Altman MR, Oltman SP, Ryckman KK, Chambers CD, Rand L, Jelliffe-Pawlowski LL

A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth.

Scientific reports

Rappoport N, Toung J, Hadley D, Wong RJ, Fujioka K, Reuter J, Abbott CW, Oh S, Hu D, Eng C, Huntsman S, Bodian DL, Niederhuber JE, Hong X, Zhang G, Sikora-Wohfeld W, Gignoux CR, Wang H, Oehlert J, Jelliffe-Pawlowski LL, Gould JB, Darmstadt GL, Wang X, Bustamante CD, Snyder MP, Ziv E, Patsopoulos NA, Muglia LJ, Burchard E, Shaw GM, O'Brodovich HM, Stevenson DK, Butte AJ, Sirota M

Comparison of risk and protective factors for preterm birth in rural, suburban, and urban Fresno County, California

Journal of Epidemiological Research

Rebecca J. Baer, Lauren Lessard, Marta Jankowska, James G. Anderson, Jessica Block, Christina D. Chambers, Jonathan Fuchs, Miriam Kuppermann, Monica R. McLemore, Gail Newel, Scott P. Oltman, Elizabeth E. Rogers, Kelli K. Ryckman, Martina A. Steurer, Jiue-An Yang, Linda S. Franck, Larry Rand, Laura L. Jelliffe-Pawlowski

Copy number variants in Ebstein anomaly.

PloS one

Giannakou A, Sicko RJ, Zhang W, Romitti P, Browne ML, Caggana M, Brody LC, Jelliffe-Pawlowski L, Shaw GM, Kay DM, Mills JL

Racial and Ethnic Disparities in Preterm Infant Mortality and Severe Morbidity: A Population-Based Study.

Neonatology

Anderson JG, Rogers EE, Baer RJ, Oltman SP, Paynter R, Partridge JC, Rand L, Jelliffe-Pawlowski LL, Steurer MA

Gestational Age and Outcomes in Critical Congenital Heart Disease.

Pediatrics

Steurer MA, Baer RJ, Keller RL, Oltman S, Chambers CD, Norton ME, Peyvandi S, Rand L, Rajagopal S, Ryckman KK, Moon-Grady AJ, Jelliffe-Pawlowski LL

Sleep Disorder Diagnosis During Pregnancy and Risk of Preterm Birth.

Obstetrics and gynecology

Felder JN, Baer RJ, Rand L, Jelliffe-Pawlowski LL, Prather AA

Epidemiology of Live Born Infants with Nonimmune Hydrops Fetalis-Insights from a Population-Based Dataset.

The Journal of pediatrics

Steurer MA, Peyvandi S, Baer RJ, MacKenzie T, Li BC, Norton ME, Jelliffe-Pawlowski LL, Moon-Grady AJ

Risk of preterm birth by maternal age at first and second pregnancy and race/ethnicity.

Journal of perinatal medicine

Baer RJ, Yang J, Berghella V, Chambers CD, Coker TR, Kuppermann M, Oltman SP, Rand L, Ryckman KK, Muglia LJ, Chung PJ, Jelliffe-Pawlowski LL

The association of maternal lymphatic markers and critical congenital heart defects in the fetus-A population based case-control study.

American journal of medical genetics. Part A

Steurer MA, Norton ME, Baer RJ, Shaw GM, Keating S, Moon-Grady AJ, Chambers CD, Jelliffe-Pawlowski LL

Dynamic outcome prediction in a socio-demographically diverse population-based cohort of extremely preterm neonates.

Journal of perinatology : official journal of the California Perinatal Association

Steurer MA, Anderson J, Baer RJ, Oltman S, Franck LS, Kuppermann M, Rand L, Ryckman KK, Partridge JC, Jelliffe-Pawlowski LL, Rogers EE

Risk of recurrent preterm birth among women according to change in partner.

Journal of perinatal medicine

Baer RJ, Yang J, Chambers CD, Ryckman KK, Saftlas AF, Berghella V, Schetter CD, Shaw GM, Stevenson DK, Jelliffe-Pawlowski LL

Risk of preterm birth among women using drugs during pregnancy with elevated a-fetoprotein.

Journal of perinatology : official journal of the California Perinatal Association

Baer RJ, Chambers CD, Ryckman KK, Oltman SP, Norton ME, Jelliffe-Pawlowski LL

Persistent Pulmonary Hypertension of the Newborn in Late Preterm and Term Infants in California.

Pediatrics

Steurer MA, Jelliffe-Pawlowski LL, Baer RJ, Partridge JC, Rogers EE, Keller RL

Acylcarnitine Profiles Reflect Metabolic Vulnerability for Necrotizing Enterocolitis in Newborns Born Premature.

The Journal of pediatrics

Sylvester KG, Kastenberg ZJ, Moss RL, Enns GM, Cowan TM, Shaw GM, Stevenson DK, Sinclair TJ, Scharfe C, Ryckman KK, Jelliffe-Pawlowski LL

Critical congenital heart defects and abnormal levels of routinely collected first- and second-trimester biomarkers.

American journal of medical genetics. Part A

Borelli M, Baer RJ, Chambers CD, Smith TC, Jelliffe-Pawlowski LL

Copy-number variant analysis of classic heterotaxy highlights the importance of body patterning pathways.

Human genetics

Hagen EM, Sicko RJ, Kay DM, Rigler SL, Dimopoulos A, Ahmad S, Doleman MH, Fan R, Romitti PA, Browne ML, Caggana M, Brody LC, Shaw GM, Jelliffe-Pawlowski LL, Mills JL

Recurrence of Preterm Birth and Early Term Birth.

Obstetrics and gynecology

Yang J, Baer RJ, Berghella V, Chambers C, Chung P, Coker T, Currier RJ, Druzin ML, Kuppermann M, Muglia LJ, Norton ME, Rand L, Ryckman K, Shaw GM, Stevenson D, Jelliffe-Pawlowski LL

Population-based risks of mortality and preterm morbidity by gestational age and birth weight.

Journal of perinatology : official journal of the California Perinatal Association

Baer RJ, Rogers EE, Partridge JC, Anderson JG, Morris M, Kuppermann M, Franck LS, Rand L, Jelliffe-Pawlowski LL

Interpregnancy interval after live birth or pregnancy termination and estimated risk of preterm birth: a retrospective cohort study.

BJOG : an international journal of obstetrics and gynaecology

Shachar BZ, Mayo JA, Lyell DJ, Baer RJ, Jeliffe-Pawlowski LL, Stevenson DK, Shaw GM

Risk of preterm birth by subtype among Medi-Cal participants with mental illness.

American journal of obstetrics and gynecology

Baer RJ, Chambers CD, Bandoli G, Jelliffe-Pawlowski LL

Survival and Major Morbidity of Extremely Preterm Infants: A Population-Based Study.

Pediatrics

Anderson JG, Baer RJ, Partridge JC, Kuppermann M, Franck LS, Rand L, Jelliffe-Pawlowski LL, Rogers EE

Reply.

American journal of obstetrics and gynecology

Norton ME, Kuppermann M, Jelliffe-Pawlowski LL

Racial-ethnic differences in midtrimester maternal serum levels of angiogenic and antiangiogenic factors.

American journal of obstetrics and gynecology

Yang J, Pearl M, DeLorenze GN, Romero R, Dong Z, Jelliffe-Pawlowski L, Currier R, Flessel M, Kharrazi M

First trimester pregnancy-associated plasma protein-A and birth weight.

European journal of obstetrics, gynecology, and reproductive biology

Baer RJ, Lyell DJ, Norton ME, Currier RJ, Jelliffe-Pawlowski LL

Inflammatory biomarkers and spontaneous preterm birth among obese women.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Wallenstein MB, Jelliffe-Pawlowski LL, Yang W, Carmichael SL, Stevenson DK, Ryckman KK, Shaw GM

Cell-free DNA vs sequential screening for the detection of fetal chromosomal abnormalities.

American journal of obstetrics and gynecology

Norton ME, Baer RJ, Wapner RJ, Kuppermann M, Jelliffe-Pawlowski LL, Currier RJ

Gestational dating by metabolic profile at birth: a California cohort study.

American journal of obstetrics and gynecology

Jelliffe-Pawlowski LL, Norton ME, Baer RJ, Santos N, Rutherford GW

Outcomes of pregnancies with more than one positive prenatal screening result in the first or second trimester.

Prenatal diagnosis

Baer RJ, Currier RJ, Norton ME, Flessel MC, Goldman S, Towner D, Jelliffe-Pawlowski LL

Detection Rates for Aneuploidy by First-Trimester and Sequential Screening.

Obstetrics and gynecology

Baer RJ, Flessel MC, Jelliffe-Pawlowski LL, Goldman S, Hudgins L, Hull AD, Norton ME, Currier RJ

Exome Sequencing of Neonatal Blood Spots and the Identification of Genes Implicated in Bronchopulmonary Dysplasia.

American journal of respiratory and critical care medicine

Li J, Yu KH, Oehlert J, Jeliffe-Pawlowski LL, Gould JB, Stevenson DK, Snyder M, Shaw GM, O'Brodovich HM

Maternal characteristics and mid-pregnancy serum biomarkers as risk factors for subtypes of preterm birth.

BJOG : an international journal of obstetrics and gynaecology

Jelliffe-Pawlowski LL, Baer RJ, Blumenfeld YJ, Ryckman KK, O'Brodovich HM, Gould JB, Druzin ML, El-Sayed YY, Lyell DJ, Stevenson DK, Shaw GM, Currier RJ

Maternal serum markers, characteristics and morbidly adherent placenta in women with previa.

Journal of perinatology : official journal of the California Perinatal Association

Lyell DJ, Faucett AM, Baer RJ, Blumenfeld YJ, Druzin ML, El-Sayed YY, Shaw GM, Currier RJ, Jelliffe-Pawlowski LL

Maternal factors associated with the occurrence of gastroschisis.

American journal of medical genetics. Part A

Baer RJ, Chambers CD, Jones KL, Shew SB, MacKenzie TC, Shaw GM, Jelliffe-Pawlowski LL

Undiagnosed metabolic dysfunction and sudden infant death syndrome--a case-control study.

Paediatric and perinatal epidemiology

Rosenthal NA, Currier RJ, Baer RJ, Feuchtbaum L, Jelliffe-Pawlowski LL

Early-onset severe preeclampsia by first trimester pregnancy-associated plasma protein A and total human chorionic gonadotropin.

American journal of perinatology

Jelliffe-Pawlowski LL, Baer RJ, Currier RJ, Lyell DJ, Blumenfeld YJ, El-Sayed YY, Shaw GM, Druzin ML

Chromosome abnormalities detected by current prenatal screening and noninvasive prenatal testing.

Obstetrics and gynecology

Norton ME, Jelliffe-Pawlowski LL, Currier RJ

Risk of critical congenital heart defects by nuchal translucency norms.

American journal of obstetrics and gynecology

Jelliffe-Pawlowski LL, Norton ME, Shaw GM, Baer RJ, Flessel MC, Goldman S, Currier RJ

Copy number variation in bronchopulmonary dysplasia.

American journal of medical genetics. Part A

Hoffmann TJ, Shaw GM, Stevenson DK, Wang H, Quaintance CC, Oehlert J, Jelliffe-Pawlowski LL, Gould JB, Witte JS, O'Brodovich HM

Risk of selected structural abnormalities in infants after increased nuchal translucency measurement.

American journal of obstetrics and gynecology

Baer RJ, Norton ME, Shaw GM, Flessel MC, Goldman S, Currier RJ, Jelliffe-Pawlowski LL

Metabolic heritability at birth: implications for chronic disease research.

Human genetics

Ryckman KK, Smith CJ, Jelliffe-Pawlowski LL, Momany AM, Berberich SL, Murray JC

Combined elevated midpregnancy tumor necrosis factor alpha and hyperlipidemia in pregnancies resulting in early preterm birth.

American journal of obstetrics and gynecology

Jelliffe-Pawlowski LL, Ryckman KK, Bedell B, O'Brodovich HM, Gould JB, Lyell DJ, Borowski KS, Shaw GM, Murray JC, Stevenson DK

Association between maternal characteristics, abnormal serum aneuploidy analytes, and placental abruption.

American journal of obstetrics and gynecology

Blumenfeld YJ, Baer RJ, Druzin ML, El-Sayed YY, Lyell DJ, Faucett AM, Shaw GM, Currier RJ, Jelliffe-Pawlowski LL

Population-based biomarker screening and the development of severe preeclampsia in California.

American journal of obstetrics and gynecology

Taché V, Baer RJ, Currier RJ, Li CS, Towner D, Waetjen LE, Jelliffe-Pawlowski LL

Obstetric, perinatal, and fetal outcomes in pregnancies with false-positive integrated screening results.

Obstetrics and gynecology

Baer RJ, Currier RJ, Norton ME, Flessel MC, Goldman S, Towner D, Jelliffe-Pawlowski LL

A genome-wide association study (GWAS) for bronchopulmonary dysplasia.

Pediatrics

Wang H, St Julien KR, Stevenson DK, Hoffmann TJ, Witte JS, Lazzeroni LC, Krasnow MA, Quaintance CC, Oehlert JW, Jelliffe-Pawlowski LL, Gould JB, Shaw GM, O'Brodovich HM

High quality genome-wide genotyping from archived dried blood spots without DNA amplification.

PloS one

St Julien KR, Jelliffe-Pawlowski LL, Shaw GM, Stevenson DK, O'Brodovich HM, Krasnow MA

Association of early-preterm birth with abnormal levels of routinely collected first- and second-trimester biomarkers.

American journal of obstetrics and gynecology

Jelliffe-Pawlowski LL, Shaw GM, Currier RJ, Stevenson DK, Baer RJ, O'Brodovich HM, Gould JB

Risk of bronchopulmonary dysplasia by second-trimester maternal serum levels of a-fetoprotein, human chorionic gonadotropin, and unconjugated estriol.

Pediatric research

Jelliffe-Pawlowski LL, Shaw GM, Stevenson DK, Oehlert JW, Quaintance C, Santos AJ, Baer RJ, Currier RJ, O'Brodovich HM, Gould JB

Triple-marker prenatal screening program for chromosomal defects.

Obstetrics and gynecology

Kazerouni NN, Currier B, Malm L, Riggle S, Hodgkinson C, Smith S, Tempelis C, Lorey F, Davis A, Jelliffe-Pawlowski L, Walton-Haynes L, Roberson M

Infant C677T MTHFR polymorphism and severe mental retardation.

Birth defects research. Part A, Clinical and molecular teratology

Shaw GM, Jelliffe-Pawlowski L, Nelson V, Zhu H, Harris JA, Finnell RH

Effect of magnitude and timing of maternal pregnancy blood lead (Pb) levels on birth outcomes.

Journal of perinatology : official journal of the California Perinatal Association

Jelliffe-Pawlowski LL, Miles SQ, Courtney JG, Materna B, Charlton V

Risks for severe mental retardation occurring in isolation and with other developmental disabilities.

American journal of medical genetics. Part A

Jelliffe-Pawlowski LL, Shaw GM, Nelson V, Harris JA

Neurodevelopmental outcome at 8 months and 4 years among infants born full-term small-for-gestational-age.

Journal of perinatology : official journal of the California Perinatal Association

Jelliffe-Pawlowski LL, Hansen RL

Risk of mental retardation among children born with birth defects.

Archives of pediatrics & adolescent medicine

Jelliffe-Pawlowski LL, Shaw GM, Nelson V, Harris JA

Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation.

Annals of neurology

Nelson KB, Grether JK, Croen LA, Dambrosia JM, Dickens BF, Jelliffe LL, Hansen RL, Phillips TM